PHARMACOLOGY TOTAL RECALL

Antibiotic used in cases of meningitis is under the family of ? -Cell wall inhibitors ? Macrolides ? Aminoglycosides ?

-Cell wall inhibitors

Drug used to treat diabetes insipidus?

vasopressin / desmopressin

Best disinfectant against TB - alcohol ? Phenol ? Quaternary ammonium compounds ? lodine ?

alcohol

Irritant to the stomach of dog

ibuprofen

MOA of sulfonamides

competitive antagonism

Difference between enrofloxacin and ciprofloxacin - 3x potent ang enro or cipro or vice versa , more stable in acid ? Ciprofloxacin more potent than enro?

Ciprofloxacin more potent than enro

MOA of ivermectin

Ivermectin causes an influx of Cl- ions through the cell membrane of invertebrates by activation specific ivermectin - sensitive ion channels . The resultant hyperpolarization leads t muscle paralysis . GABA binding ability

Which of the following is an example of systemic route of drug administration

intrapleural

Which of the following is an example of local route of drug administration

-intraarticular

Drug of choice for chlamydiasis-?

oxytetracycline

Antibiotic that does not cross the BBB -trimetophrim ? aminoglycosides macrolides? Beta lactams?

beta lactams

Property of an antibiotic making it to pass the BBB-?

non - protein bound non - ionized ( highly lipid soluble )

Withdrawal period of TMPS

10 days

Withdrawal period of Amoxicillin - 10 days ? 15 days ? 20 days ? 30 days ?

3 days ( poultry ) , 7 days if oral , 18 days inj . ( swine ) , 20 days cattle

Withdrawal period of Oxytetracycline in poultry- 5 days ? 7 days?

7 days (pvet)

Antidote for malathion poisoning

atropine

Acepromazine is an example of pre - anesthetic . It can be used together with?

-xylazine

Chlorpromazine is contraindicated in horses because ? - it can cause ataxia ? Horsecannot metabolize it ? Anaphylaxis ?

it can cause ataxia and penile paralysis

Chlorpromazine is contraindicated in horses because ? - it can cause ataxia ? Horsecannot metabolize it ? Anaphylaxis ?

- it can cause ataxia and penile paralysis

Can cause drowsiness

sedative

Anticoccidial that antagonistic with tiamulin?

-monensin

Nutrient derived from tryptophan

niacin

Vitamin needed for the metabolism of amino acid

biotin

Vitamin E is easily decomposed by - alkali ? Acid ? Heat ? Light ?

Light

Vitamin A is easily decomposed by - alkali ? Acid ? Heat ? Light ?

Light

The senior vet prescribed methazolamide . It is indicated for ?

glaucoma

What would be the best anthelmentic to use against worm larvae of dogs ? -ivermectin ? Fenbendazole ? Pyrantel ? Piperazine ?

Pyrantel

Which of the following has the highest therapeutic index ? - penicillin ? Gentamicin ? Sulfa ?

Gentamicin

Most easily controlled anesthetic ? Halothane ? Methoxyflurane ?nota?

NOTA. Based sa book (isoflurane)

Treatment of DIC -? Disseminated Intravascular Coagulation

heparin sulfate

Glucagon is indicated during ?

decrease blood glucose

Withdrawal period of oxytetracline in salmonids ?

21 days

a potassium sparing effect?

spironolactone

The flock was treated with tilmicosin onapril 5. when will it be safe to be slaughtered to avoid antibiotic residue ?

april 20- 10 days withdrawal period

The swine was treated with tilmicosin onapril 5. when will it be safe to be slaughtered to avoid antibiotic residue

10 days withdrawal period

There are 200 cattle in the herd . Available drug is oxytetracycline 100 mg / bottle . How many bottles do you need to prevent anaplasmosis throughout the tick season ?

do Assume body weight of cattle ( 250 kg ) , must know the preventive dose for oxytet ( 20 mg / kg ? )

Time when TAT is given to foals if the mare is vaccinated before foaling ?

3 months

Withdrawal period of levamizole

- 7 days

Withdrawal Norfloxacin in layer is administered through ?

Drinking water

organophosphate for horses

dichlorvos

op antidote

atropine

Fluid to give when there . severe dehydration and diarrhea

lactated ringers

The dog's skin was burned by caustic soda . Which of the following will you use to treat the wound ?

Virgin coconut oil

atropine is for what receptor ?

muscarinic

atropine has similar effects with?

mushroom poisoning

MOA of Ivermectin?

GABA Inhibitor

MOA Sulfonamides

DNA synthesis inhibitor

MOA of vincristine which can make it effective for TVT

mitotic spindle function inhibitor

Not given in horses

minocycline , monensin

, Causes discoloration of teeth in young animals?

TCN

always accompany atropine in OP poisoning

= 2 pam

avoid giving antitussives when?

when there is non - productive cough

to pass the BBB , a molecule should be =?

lipophilic

treatment for anaplasma

tetracycline

Fipronil is an?

acaricide

Fipronil distribution is through?

diffusion

a loop diuretics?

furosemide

Which drug is cns stimulant in low dose but toxic in high dose ? -cocaine , theobromine , amitriptyline , strychnine

theobromine

Which is not antagonist of the effect of atropine ?

Pilocarpine

Give folic acid to prevent anemia in dogs . Dosaging of folic acid ?

2.5 mg bid

Penicillin computation in IU

20,000 IU / kg

Computation of ketamine

11mg / kg cat

Sulfa not being used in layer

high tendency of drug residue in egg

Drug used for CBPP when released after quarantine

TCN or Tylosin

Shipping fever , metaphylaxis stage

TCN

Site of action of furosemide

thick ascending limb of loop of henle

Withdrawal period of anthrax vaccine

60 days

Do not belong ? PCN , TCN , Linco , Chloram

PCN ,

Enroflox , when is safe to use in dogs ?

Too old

Drug with broad therapeutic index

old Penicillin ( beta lactams )

Fecalysis revealed hookworm , dipylidium , toxocara ? Which antihelmintic is to be used ?

fenbendazole

OP that causes cerebral agenesis when sprayed in pregnant sow ?

Lindane

Longest withdrawal period ?

Topical or injectable ivermectin

Treatment for shock after administration of combined bacterin - Dexa or epinephrine?

epinephrine

The drug most likely to cause gastrointestinal ulceration or erosion in a dog ?

Ibuprofen

Used to control vomiting in Parvovirus infection in dog ?

metoclopramide

When to use colloids ? a . increase extracvascular volume b . increase intravascular volume

b . increase intravascular volume

Anticonvulsant for post - distemper epilepsy ?

phenobarbital

Anticonvulsant for dog that sniffed -- ?

Diazepam

After 6 hours , cat still have seizures after OP intoxication ?

prolonged AchE inhibition

Epinehprine in anaphylactoid shock to

increase heart rate and blood pressure

For treatment of TVT ?

vincristine

Computation Note B₁ - thiamine , B2- riboflavin

Drug A ( 2 % ) for 8kg , 3mg / kg every 4 hours . How many to administer on first day

increase extracvascular volume b . increase intravascular volume Anticonvulsant for post - distemper phenobarbital epilepsy ? Computation B2-

Drug A ( 2 % ) for 8kg , 3mg / kg every 4 hours . How many to administer on first day ?

1.2mi / dose 7.2ml / day

Drug B ( 10ppm ) 10mg / pig / day for 100 pigs . How many of the drug per day ?

= 100kg / day

Test for rate of excretion of drug ?

K * excretion

Not in dehydration with vomiting and diarrhea ? A. LRS b . 0.9 % saline c . 5 % dextrose d . 5 % amino acid

d . 5 % amino acid

Pre - anesthetic that causes vomiting in dog ? a.xylazineb . ketamine c.acepromazine d . atropine

a.xylazine

Main site of drug excretion ?

kidney / urine

Action of Doxapram ?

enhance breathing

OP antidote

atropine

Dosage of atropine as antidote ?

0.2-2mg / kg

Yellow taint on humerus , adverse effect of ?

tetracycline

Major adverse effect of penicillins ?

hypersensitivity

Ibuprofen is contraindicated in ?

cats

Excretion of spironolactone ? a . chelation b . hydrolysis ?

b . hydrolysis ?

Effect of enrofloxacin ?

articular cartilage erosion

To enhance excretion of barbiturates

cartilage alkalinize urine

barbiturates Not to be used in food - producing animal ?

chloramphenicol

Furosemide dosage and frequency 5 mg 4 mg

5 mg / kg ( 2-4mg / kg IV IM every 1-6hrs ) merck