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What are metabolic activities?
Chemical activities that occur within our body cells all the time
What are metabolic waste products?
Substances produced in metabolic reactions that are harmful or toxic to our bodies
What are some metabolic waste products?
Carbon dioxide
Urea
Mineral salts or ions
Water
What is excretion?
The remoal of metabolic waste products, toxic substances and substances in excess of the body’s requirement
What are excess mineral salts, excess water and urea excreted as?
Urine and sweat from kidneys and skin
What are carbon dioxide and water vapour excreted as?
Gas in exhaled air from the lungs
Carbon dioxide and water are products of aerobic respiration. (T/F)
True
When there is an abnormally high level of carbon dioxide in the blood, …
a condition called hypercarbia occurs where a person might suffer from headache, confusion, rapid breathing and premature heartbeats
How is urea produced?
Absorbed amino acids are transported to the liver, distributed around the body and then assimilated, to synthesise proteins found in the blood plasma like fibrinogen used in blood clotting
When there is an abnormally high urea concentration in the blood, it may cause :
abdominal pain, nausea and vomiting
In rare cases, irregular heartbeats and muscle cramps
Why are excess salts and ions harmful?
They may lower the water potential in the blood plasma, making the blood more concentrated, causing water to pass out of cells and into the blood by osmosis. The cells become dehydrated.
Why is excess water harmful to our body?
Excess water increases blood plasma’s water potential, causing water molecules to move from blood plasma into tissue cells by osmosis, making the cells swell and burst
Why is excretion important?
The body excretes metabolic waste products like urea and toxic substances so that they do not accumulate to a level that becomes harmful to the body
What do people use to get rid of the body odour caused by sweat?
People use antiperspirant that contains aluminium which blocks sweat ducts and reduces the amount of sweat that reaches the skin surface
What does the human urinary system contain?
A pair of kidneys
A pair of ureters
A urinary bladder
Urethra
What is the shape and size of a kidney?
The kidneys are a bean-shaped organs
What is the function of kidneys?
The main function is to excrete erua and excess salt and water as urine
What does each kidney contain?
Numerous nephrons
What is the ureter?
The ureter is a narrow tube that connects the kidney to the urinary bladder, which is where urine passes through
What is the urinary bladder?
The urinary bladder is an elastic muscular bag that stores urine
What is the urethra?
The urethra is the duct through which urine passes from the bladder to outside the body
What are nephrons?
Nephrons are the basic functional units of the kidney which are tiny kidney tubules where urine is formed
What are the parts of a nephron?
Bowman’s capsule
Proximal convoluted tubule
Loop of Henle
Distal convoluted tubule
Several nephrons open into a tube called the …
collecting duct
Bowman’s capsule is a …
cup-like structure
The proximal convoluted tubule is the …
first coiled tubule
The distal convoluted tubule is the …
second coiled tubule
The loop of Henle is a …
U shaped tubule
The collecting duct is a …
straight tubule that leads to the ureter
Explain the process of how blood enters a nephron
Nephrons are surrounded by blood capillaries that are connected to the renal artery and renal vein. Blood enters the kidney by the renal artery and branches to form the afferent arteriole which brings blood into the glomerulus. Each arteriole further braches into a mass of blood capillaries in the Bowman’s capsule known as glomerulus. An efferent arteriole transports blood away from the glomerulus. Blood leaving the glomerulus continues into blood capillaries surrounding the nephron. These blood capillaries unite to form venule, which lead into a branch of the renal vein
Blood enters the kidney by the renal artery and leaves the kidney by the …
renal vein
What are the 2 main processes for urine formation?
Ultrafiltration
Selective reabsorption
What does ultrafiltration involve?
High blood pressure in the glomerulus as afferent arteriole is wider than efferent arteriole
Blood plasma is forced out of glomerular blood capillaries into Bowman’s capsule
Filtered blood plasma called glomerular filtrate contains small, soluble molecules like salt, water, glucose, amino acids, and urea
How is the glomerulus suited to urine formation?
It is a network of blood capillaries which provides a large surface area for filtration to occur
Blood capillaries have one-cell-thick walls and tiny pores in them
Blood capillaries are covered by a thin, partially permeable membrane that only allows small molecules to pass through. It is impermeable to blood cells, platelets and large molecules like proteins
In a normal adult, how much glomerular filtrate is produced per minute?
120cm3
What is selective reabsorption?
It is the process where only substances the body needs are reabsorbed, like most water via osmosis, some salts, and all glucose and amino acids via active transport
What are waste products that are passed out of the nephron as urine?
Excess water
Urea
Mineral salts
What is reabsorbed in the proximal convoluted tubule?
Most water via osmosis
Most mineral salts via active transport and diffusion
All glucose and amino acids via active transport
What is reabsorbed in the distal convoluted tubule?
Some water via osmosis
Some mineral salts via active transport
What is reabsorbed in the loop of Henle?
Some water via osmosis
Some mineral salts via osmosis
What is reabsorbed in the collecting duct?
Some water via osmosis
What is osmoregulation?
Osmoregulation is the control of water potential and solute concentration in the blood to maintain a constant water potential in the body
If the blood plasma becomes too diluted, …
water will enter the blood cells by osmosis. The blood cells will swell and even burst. The tissue cells will also swell because water from blood plasma will move into cells
If the blood plasma becomes too concentrated, …
water will move out of the cells by osmosis. The body cells and tissue cells will become completely dehydrated and shrink. They will not be able to perform metabolic functions properly, which is possibly fatal
What controls the amount of water in the blood plasma?
Anti-diuretic hormone(ADH)
Where is the ADH produced?
ADH is produced by a region of the brain called the hypothalamus
How is ADH released?
It is released by the pituitary gland
ADH increases,,,
water absorption at the collecting duct
What are kidneys’ role in osmoregulation?
They are osmoregulators, because they help to regulate the water potential and solute concentration in the blood
When water potential of blood plasma increases above the normal level, …
The hypothalamus detects the increase in water potential of the blood. The pituitary gland is stimulated to secrete less ADH into the bloodstream. Cells in the walls of the collecting duct become less permeable to water. Less water is reabsorbed from the collecting duct into the surrounding blood capillaries. A larger volume of dilute urine is produced. Water potential of blood decreases to normal level.
When water potential of blood decreases below the normal level, ….
The hypothalamus detects the decrease in water potential of blood. The pituitary gland is stimulated to secrete more ADH into the bloodstream. Cells in the walls of the collecting duct become more permeable to water. More water is reabsorbed from the collecting duct into the surrounding blood capillaries. A smaller volume of concentrated urine is produced. Water potential of blood increases to normal level.
Why are kidneys important?
The kidneys are osmoregulators and are excretory organs.
As excretory organs, …
the kidneys excrete metabolic waste produts like urea, excess water, mineral salts, in the form of urine.
As osmoregulators, …
the kidneys regulate the solute concentration and water potential in the blood, maintaining a constant water potential in the blood