Viral diseases 2

measles virus - DNA virus from the paramyxovirus family

etiology of measles

measles

Caused by rubeola

measles

fever respiratory symptoms, rash, spreads through airborne droplets through respiratory tract

measles

Produce koplik's spot

measles

caused by rubella virus

german measles

contagious disease caused by toga virus family

german measles

fever respiratory symptoms and rash

german measles

Cause congenital defects in developing fetus

german measles

Disease of the children

Seasonal

7-10 days

incubation period of german measles

Prodromal symptoms of german measles

fever malaise, conjunctivitis, photophobia, cough

Koplik’s spots

pathognomonic (small erythematous macules with white necrotic center appearing in the buccal mucosa

head and neck →> trunk →> extremities

german measles spread through

Warthin-Finkeldy Giant cells

multinucleated macrophgaes seen in lymphoid tissue

Warthin-Finkeldy Giant cells

histology of german measles

supportive therapy is needed (symptomatic care)

treatment for german measles

Koplik’s spot

red dots in mucobuccal

mumps

Acute, contagious, viral infection characterized by uni or bi lateral swelling of the salivary glands (Parotid glands)

mumps

Disease of childhood but may affect adults

2-3 weeks

incubation period of mumps

respiratory route, droplets of saliva

mode of transmission of mumps

mumps

Complications In males such as ORCHITIS

orchitis

inflammation the testes, if only 1 - not affect fertility

Maintain hydration and alimentation,

Prevention(vaccination)

treatment for mumps

clinical features of mumps

preceded by onset of headache, chills moderate fever vomiting, pain below ear - > form rubbery swelling of the salivary glands

herpangina

Acute viral infection caused by Coxsackievirus

contaminated saliva, contaminated feces if ingested

mode of transmission for herpangina

2-10 days, sytemic symptoms resolve w in a few days,

ulcer heals 7-10 days

incubation period for herpangina

herpangina

malaise, fever, dysphagia, sore throat

herpangina

vesicular eruption on soft palate, faucial pillars, tonsils,erythematous pharyngitis

clinical features of herpangina

Endemic w outbreaks typically in summer or early autumn

Self-limiting, symptomatic care

treatment of herpangina

● Fever

● Pharyngitis

● adenopathy

Clinical syndrome of infectious mononucleosis

Epstein- Barr virus

cause of infectious mononucleosis

body secretions

mode of transmission of infectious mononucleosis

infectious mononucleosis

No specific oral manifestations: acute gingivitis and stomatitis, appearance of white or gray membrane, palatal petechiae, occasional ulcers

clinical feature of infectious mononucleosis

Fever, sore throat, headache, chills

No specific treatment, symptomatic treatment

treatment of infectious mononucleosis

glandular fever

other term for infectious mononucleosis

infectious mononucleosis

kissing disease

oral manifestation of cytomegalic inclusion disease

appears 4s Common ulcers without clinical pathognominic sign

hard palate, soft palate, tongue and floor of the mouth

location of cytomegalic inclusion disease

cytomegalic inclusion disease

malaise, fever, lymphadenopathy, pneumonia, hepatosplenomegaly, and superinfection

pathognomic of cytomegalic inclusion disease

Intranuclear and cytoplasmic inclusions in the cells of salivary gland (pathognomonic)

cytomegalic inclusion disease

Inclusion bodies within cytoplasm and nuclei in enlarged infected cells of various organs of newborn infants.

vertical transmission from mother to child, infant passage thru birth canal

mode of transmission of cytomegalic inclusion disease

cytomegalic inclusion disease

Acquired disease thru blood and tissue products transplant, mother’s milk.

complications of cytomegalic inclusion disease

splenomegaly, hepatomegaly, jaundice choriorenitis, purpura, microcephaly,cerebral calcifications, blindness, deafness, mental retardation.

no specific treatment

treatment of cytomegalic inclusion disease

cytomegalic inclusion disease

salivary gland Virus disease

epidemic parotitis

other term for mumps