Insulin Preparations

Insulin major target tissues:

a. Liver

b. Fat

c. Muscle

d. a and b

e. b and c

f. All

f. All

Rapid-acting insulin preparation/s:

I. Insulin Lispro

II. Insulin Aspart

III. Insulin Glulisine

IV. Regular Insulin

V. Isophane Insulin

VI. Insulin Glargine

VII. Insulin Detemir

a. I, II, III, IV, V, VI, VII

b. I, II, III

c. IV

d. V

e. V, VI, VII

f. VI, VII

b. I, II, III

Insulin Lispro

Insulin Aspart

Insulin Glulisine

Short-acting insulin preparation/s:

I. Insulin Lispro

II. Insulin Aspart

III. Insulin Glulisine

IV. Regular Insulin

V. Isophane Insulin

VI. Insulin Glargine

VII. Insulin Detemir

a. I, II, III, IV, V, VI, VII

b. I, II, III

c. IV

d. V

e. V, VI, VII

f. VI, VII

c. IV - Regular Insulin

Intermediate-acting insulin preparation/s:

I. Insulin Lispro

II. Insulin Aspart

III. Insulin Glulisine

IV. Regular Insulin

V. Isophane Insulin

VI. Insulin Glargine

VII. Insulin Detemir

a. I, II, III, IV, V, VI, VII

b. I, II, III

c. IV

d. V

e. V, VI, VII

f. VI, VII

d. V - Isophane Insulin

Long-acting insulin preparation/s:

I. Insulin Lispro

II. Insulin Aspart

III. Insulin Glulisine

IV. Regular Insulin

V. Isophane Insulin

VI. Insulin Glargine

VII. Insulin Detemir

a. I, II, III, IV, V, VI, VII

b. I, II, III

c. IV

d. V

e. V, VI, VII

f. VI, VII

f. VI, VII

Insulin Glargine

Insulin Detemir

Only insulin administer intravenously.

a. Regular Insulin

b. Isophane Insulin

c. Insulin Glargine

d. Insulin Detemir

e. Insulin Lispro

a. Regular Insulin

Neutral Protamine Hagedorn.

a. Regular Insulin

b. Isophane Insulin

c. Insulin Glargine

d. Insulin Detemir

e. Insulin Lispro

b. Isophane Insulin

A peak less insulin with constant amount in the plasma until its effect wear off.

a. Regular Insulin

b. Isophane Insulin

c. Insulin Glargine

d. Insulin Detemir

e. Insulin Lispro

c. Insulin Glargine

Fastest onset among the following insulin.

a. Regular Insulin

b. Isophane Insulin

c. Insulin Glargine

d. Insulin Detemir

e. Insulin Lispro

e. Insulin Lispro - it is rapid-acting.

Apidra

a. Insulin Lispro

b. Insulin Aspart

c. Insulin Glulisine

d. Regular Insulin

e. Insulin Detemir

c. Insulin Glulisine

Novolog

a. Insulin Lispro

b. Insulin Aspart

c. Insulin Glulisine

d. Regular Insulin

e. Insulin Detemir

b. Insulin Aspart

Humalog

a. Insulin Lispro

b. Insulin Aspart

c. Insulin Glulisine

d. Regular Insulin

e. Insulin Detemir

a. Insulin Lispro

Levemir

a. Insulin Lispro

b. Insulin Aspart

c. Insulin Glulisine

d. Regular Insulin

e. Insulin Detemir

f. Insulin Glargine

e. Insulin Detemir

Lantus

a. Insulin Lispro

b. Insulin Aspart

c. Insulin Glulisine

d. Regular Insulin

e. Insulin Detemir

f. Insulin Glargine

f. Insulin Glargine

Not included in premixed insulin:

a. Insulin Glargine

b. Insulin Detemir

c. Regular Insulin

d. a and b

e. b and c

f. All

d. a and b - long-acting insulins are not included in premixed insulin.

Complications of insulin therapy

a. Hypoglycemia

b. Immunopathology of Insulin Therapy

c. Lipodystrophy at Injection Site

d. a and b

e. b and c

f. All

f. All

Insulin therapy sympathetic effect:

a. Tachycardia

b. Palpitation

c. Sweating and tremulousness

d. a and b

e. b and c

f. All

f. All

Parasympathetic effect of insulin therapy:

a. Nausea

b. Hunger

c. Both

d. None

c. Both

True:

a. Hypoglycemia may progress to convulsion and coma if untreated.

b. Treatment for hypoglycemia is glucose.

c. Both

d. None

c. Both

True:

a. Insulin therapy may lead to hypersensitivity which can be local or systemic urticaria due to histamine release

b. Insulin therapy may lead to immune insulin resistance wherein lower titer of IgG anti-insulin antibodies leads to insulin resistance-lupus erythematosus

c. Atrophy of subcutaneous fatty tissue at the site of injection may occur if not injected in alternating sites

d. a and b

e. b and c

f. All

f. All

Insulin therapy may lead to immune insulin resistance wherein lower titer of __________ anti-insulin antibodies leads to insulin resistance-lupus erythematosus.

a. IgA

b. IgE

c. IgG

d. IgM

c. IgG