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Testosterone
Hormone that increases muscle growth by stimulating protein buildup in muscle cells.
Human Growth Hormone (HGH)
Hormone that promotes muscle growth and repair.
Myostatin
Molecule that slows muscle growth; mutations can lead to extreme muscle development.
Hydrostatic Skeleton
Fluid-filled chamber(s) that muscles push against (ex: earthworm).
Exoskeleton
Hard external skeleton that muscles attach to (ex: insects).
Endoskeleton
Internal framework of hardened elements where muscles attach (ex: vertebrates).
Vertebrate
Animal with a vertebral column (backbone).
Axial Skeleton
Skull, vertebral column, rib cage.
Appendicular Skeleton
Shoulder girdle, hip girdle, and limbs (or fins).
Vertebrae
Individual bones of the vertebral column separated by discs.
Spinal Cord
Runs through vertebral column; connects body to brain.
Bone
Collagen-rich, mineralized organ wrapped in connective tissue; stores minerals, supports organs, produces blood cells.
Compact Bone
Dense, outer, weight-bearing layer.
Spongy Bone
Lightweight bone with internal spaces filled with marrow.
Red Marrow
Produces blood cells; located in spongy bone.
Yellow Marrow
Stores fat; fills long bone cavities.
Osteoporosis
Condition where bones lose calcium and become weak and likely to break.
Joint
Where two bones meet.
Fibrous Joint
Bones held tightly by dense connective tissue (ex: skull bones).
Cartilaginous Joint
Bones connected by cartilage (ex: between vertebrae).
Synovial Joint
Most movable; bones held by ligaments; lubricated with synovial fluid.
Ball-and-Socket Joint
Allows rotation (shoulder, hip).
Gliding Joint
Bones slide over each other (wrist, ankle).
Hinge Joint
Movement in one plane (elbow, knee).
Arthritis
Chronic joint inflammation.
Osteoarthritis
Degenerative joint disease; common in older adults.
Rheumatoid Arthritis
Autoimmune disorder where immune system attacks synovial membrane.
Tendon
Dense connective tissue strap that connects muscle to bone.
Opposing Muscle Pairs
Muscles that reverse each other's actions (e.g., biceps vs. triceps).
Sphincter
Ring-shaped muscle controlling passage through openings.
Skeletal Muscle Fiber
Long, cylindrical, multinucleated cell containing myofibrils.
Myofibrils
Threadlike bundles inside muscle fibers containing contractile units.
Sarcomeres
Contractile units within myofibrils composed of actin and myosin.
Actin
Thin filament; interacts with myosin during contraction.
Myosin
Thick filament; motor protein that binds and pulls on actin.
Sliding-Filament Model
Explains how muscles contract by sliding actin and myosin past each other.
Creatine Phosphate Pathway
Quick ATP source; lasts 5-10 seconds.
Aerobic Respiration
Produces ATP using oxygen; supports long-duration activity.
Lactate Fermentation
Generates ATP without oxygen; used when oxygen is limited.
Red Muscle Fibers
Have myoglobin, many mitochondria; good for endurance.
White Muscle Fibers
Low myoglobin and few mitochondria; good for quick, strong bursts.
Muscle Fatigue
Decline in ability to generate force during continued activity.
Aerobic Exercise
Increases blood supply & mitochondria; improves endurance.
Strength Training
Builds more actin and myosin; increases power.
Lipoprotein Lipase (LPL)
Enzyme that helps muscles take up fatty acids and triglycerides.
Effects of Inactivity
Reduced LPL, higher blood glucose, increased risk of cardiovascular disease and diabetes; sitting too long is harmful even if you exercise.