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Viscosity of the Medication
Thicker meds need syringes with larger bore sizes
Injection Route
Affects the size/type of syringe and needle needed (IM
Animal Size and Species
Smaller animals use smaller syringes; larger animals need larger ones
Needle Compatibility
Syringe must match correct needle gauge and length for safety
18G
For thick meds and large volume injections (e.g.
20G
General-purpose needle for large dogs
21G
Standard for medium-sized dogs and cats (IV use)
22G
For precise
23G
For delicate injections (small animals
25G
Fine needle for minimal pain (rabbits
27G–30G
Extremely fine for insulin
Thick Medication Needle Size
18G–20G
Thin Medication Needle Size
22G–25G
Large Animal IM Injection
18G–22G
Small Animal IM Injection
22G–25G
Large Animal SC Injection
20G–25G
Small Animal SC Injection
22G–25G
Large Animal IV Injection
18G–22G
Small Animal IV Injection
22G–25G
ID Injection Needle Size
25G–30G
½ inch needle (12 mm)
For SC & ID in small animals
⅝ inch needle (16 mm)
For SC injections and vaccines in small animals
1 inch needle (25 mm)
For IM in small animals and IV in cats/dogs
1½ inch needle (38 mm)
For IM in medium/large dogs
2 inch needle (50 mm)
For deep IM or IV in large animals