PTCB Interactions

What should not be taken with statin drugs due to an increase in muscle pain and aches?

Grapefruit

Antiplatelet drugs like clopidogrel should not be taken with what because of an increase risk in bleeding?

NSAIDS like celecoxib and ibuprofen and anticoagulant drugs like warfarin and heparin

Which drugs should not be mixed with multivalent ions like calcium, magnesium, and iron due to a reduction of effectiveness in the drugs?

Levothyroxine, Fluoroquinolones like ciprofloxacin and moxifloxacin, Bisphosphonates like alendronic acid and fosamax, Pamidronates like aredia, and tetracyclines like tetracycline and minocycline

What should not be taken with Nitrates due to an increased risk of severe hypotension?

PDE5 inhibitors like tadalafil and sildenafil

What should not be taken with ACE inhibitors like ramipril and lisinopril due to an increase risk of hyperkalemia?

Potassium elevating drugs

What should not be taken with Ritonavir because it would lower the needed dose?

Protease inhibitors like lopinavir

What should not be taken with beta blockers like atenolol due to the increase risk of heart failure and bradycardia?

Calcium channel blockers like amlodipine

What should not be taken with broad spectrum antibiotics due to the increase risk of bleeding?

Warfarin (Glucophage)

What should not be taken with Digoxin due to an increase risk of toxicity?

Loop or thiazide diuretics

What should not be taken with Aminoglycosides due to an increased risk of toxicity and kidney damage?

Loop diuretics

What should not be taken with Antihistamines due to their increase risk of sedation?

Benzodiazepines, SSRIs, and Antipsychotic drugs

What should not be taken together due to an increased risk of arrhythmias?

Macrolides, Amiodarone, SSRIs, Fluoroquinolones, Quinine, and Antipsychotic drugs

What should not be taken with Corticosteroids like prednisone and hydrocortisone due to the increase risk of peptic ulcerations and GI bleeding?

NSAIDS like ibuprofen

Which medications should not be mixed due to their increase risk of hypertensive crisis?

MAO inhibitors like isocarboxazid, tranylcypromine, and phenelzine and tyramines.

What should not be taken with Omeprazole due to the risk of reducing antiplatelet effects?

Clopidogrel

What should not be taken with Macrolides due to the increase risk of adverse effects?

Statins

What medications should not be mixed to their increase risk of hypoglycemia?

Sulfonylureas, metformin, and thiazolidinediones

What medications should not be taken together due to the increase risk of hypokalemia?

Corticosteroids, Beta-2 agonists like Albuterol and terbutaline

What should not be taken with Phenytoin (Dilantin) due to reducing their clinical effects?

Warfarin and estrogen (progesterone)

What should not be taken with Alpha blockers due to the risk of dangerously low blood pressure?

Antihypertensive drugs