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Alzheimer’s disease
Degenerative disease of the brain
Early-onset: occurs before 60; rare; genetic component
Late-onset: occurs after 60; more common; may have genetic component but lifestyle factors may also play a role
Strongest risk factor for Alzheimer’s
Age - by age 85, 50% of individuals show signs
Asthma
Inflammatory disease that causes constriction of the bronchial tubes, preventing air to pass freely
Children have highest rates
Risk factors for asthma
More common in developed countries
In urban areas
Common among Black and African Americans
Sedentary lifestyle and obesity linked to risk
Diathesis-stress model for asthma
Genetic variability
Respond with an allergic reaction to certain substances in the environment
Hygiene hypothesis
asthma results from the cleanliness that is common in modern societies
Treatment for asthma
Minimizing attacks
Requires medication
Diabetes
disorder caused by insulin deficiency
Type 1: Insulin-dependent
Autoimmune disorder
Caused mainly by genetic factors
occurs usually before age of 30
cannot produce insulin
no cure
non-Hispanic white individuals
No longer called “juvenile-onset diabetes” because older adults can still get it
Type 2: Non-insulin dependent
More common
Mainly caused by lifestyle factors
Ethnic minorities (Hispanics, Nativ Americans, and Black people)
No longer called “Adult-onset” diabetes because more juvenile kids are getting it
risk for Type 1 and Type 2 diabetes between ethnic groups
Type 1: non-Hispanic white individuals
Type 2: Ethnic minorities (Hispanics, Native Americans, and Black people)
Pima Indian groups in Mexico vs. the United States
Pima Indian groups in Mexico
Rate of diabetes was 6.9%
Pima Indian groups in United States
The rate of diabetes was 38%
Why?
Pima Indians also have much higher rates of obesity
Pima Indians thought to have “thrifty gene” that increases risk of diabetes
U.S. Pima Indians farm and grow most of their own food
have low levels of occupational physical activity
Even with genetic predisposition, rates of diabetes largely influenced by environment and are preventable
leading cause of death for Type 1 and Type 2
Type 1: renal disease
Type 2: cardiovascular disease
HIV
human immunodeficiency virus; causes the development of AIDS
AIDS
acquired immune deficiency syndrome; the immune system loses effectiveness
HIV’s Relation to it: Sexual contact & drug use
main risk groups for HIV
Overall, Black/African American people account for the largest number of estimated new HIV infections
Primary prevention
changing behavior to decrease transmission of HIV
Limiting # of sexual partners
Use condoms
Don’t share needles
Secondary prevention
helping people live with infection
Encouraging HIV testing
Coping with HIV diagnosis
Tailoring interventions to person’s specific situation
Finding meaning
History of drinking habits
In colonial America drinking was much more common than it is today.
In 1920, the sale of alcoholic beverages was outlawed (prohibition) which lowered per capita consumption
When this amendment was repealed in 1934, consumption rose sharply.
About ⅔ of U.S. adults classified as current drinkers currently
Beer
12 fl oz
Wine
5 fl oz
Malt liquor
8-9 fl oz
Gin, rum, tequila, vodka, whiskey, etc
1.5 fl oz (40% alcohol)
Who has the highest rate of drinking?
Adults age 25-44
What gender is more likely to drink?
Men
Education and drinking
People with more education are more likely to drink, but those without high school education more likely to develop drinking problems, and second lowest for any consumption in the last month
Race and drinking
Asians are the lowest for binge drinking and heavy drinking
Body composition
In women, a greater percentage of body mass is fat compared to men
Result: The concentration of alcohol is increased in the female bloodstream (muscle has more blood supply)
Stomach ADH
Women have less of this enzyme compared to men
Result: Women do not metabolize alcohol before it gets out of the stomach. Therefore the blood alcohol concentration (BAC) is higher for women
Liver ADH
Women have a less active form of this enzyme than do men.
Result: Women do not metabolize alcohol as efficiently, thereby increasing BAC
Tolerance
The more you use a drug, the more of that drug you will need to get the same effects
Dependence
The body becomes so reliant on a drug that it needs that drug in order to function “normally”
Direct hazards of alcohol use
harmful physical effect of alcohol itself
Indirect hazards of alcohol use
Consequences resulting from psychological and physiological impairments produced by alcohol
the amount of alcohol consumed and mortality
J-shaped curve
Non-drinkers and heavy drinkers are at increased risk of mortality and number of drinks per day
Light to moderate drinkers have the best prospects for good health
Alcohol and heart disease
Heavy drinking related to heart disease and stroke
Light moderate drinking may lower heart disease deaths
Disease model
People with problem drinking have the disease of alcoholism
Strongly influenced the medical community
Two most common types of alcoholism: Gamma - loss of control once drinking begins & Delta - Inability to abstain
Tension Reduction model
People drink alcohol as a means of coping with tension
Sedative, so capable of producing physiological relaxation
Effect varies across people and is influenced by expectancy (expect to get drunk then you might)
Alcohol Myopia Model
People drink because it makes them feel better about themselves and alters their thought process
Effects include: Self-inflation, Relief from worry, Increased aggression, Increased friendliness, Exaggerated sexual behaviors
Social Learning Model
Drinking is a learned behavior and is acquired in the same way as other learned behaviors
Positive Reinforcement (like the taste)
Negative Reinforcement (to escape from an unpleasant situation)
Modeling (learning to drink through others)
Alcoholics Anonymous
Alcohol prevention class
Follows the disease model
If deemed an alcoholic, then always an alcoholic (sustained effort)
Focused on abstinence from alcohol
Stimulants
produce alertness, elevate mood, decrease appetite
Caffeine
Cocaine
Amphetamines
Nicotine
Sedatives/depressants
induce relaxation by lowering activity of the brain, muscles, heart
Barbiturates
Tranquilizers
Opiates
Alcohol
Hallucinogens
Serotonin is involved in feelings of well-being and perceptual distortions
Ecstasy (MDMA)
LSD
Abuse
frequent, heavy consumption that results in damage to one’s health
Treatment to drug abuse
Goal is total abstinence
Narcotics Anonymous
Treatments are similar to alcohol treatments
Relapse programs that are individualized may be especially helpful
Positive Reinforcement
They enjoy the taste and its positive effects
Negative Reinforcement
Drinking allows escape from an unpleasant situation
Leptin
a protein, signals when more food is needed
Insulin
a hormone, helps the hypothalamus understand when we have eaten enough food
Ghrelin
a hormone, stimulates appetite and decreases metabolism
Two things for your body to maintain
Stable weight occurs when calories eaten equal those expended for body metabolism and physical exercise
Metabolic rates differ from person to person
Obesity Stigma
Obese people are viewed as less attractive, socially adept, intelligent and productive than their peers.
Standard model is 5’11 and 110 pounds
7 inches taller and 55 lbs lighter than average US woman
experimental starvation
Key’s WWII study
Physical Effects of human starvation
During WWII - severely restricted diet for 6 months instead of war
Drastic weight loss over short period leads to irritability, aggression, and preoccupation with food
experimental overeating
Sim’s Vermont Prison study
Incarcerated individuals at a prison in Vermont volunteered to gain 20 to 30 lbs by overeating
Not as miserable as those drastically undereating, but started to find food unpleasant, having to force themselves to eat
Differences in difficulty returning to starting weight - family history of obesity for those with more difficulty
Biological Influences on weight
As weight fluctuates, hormones stimulate changes in metabolism and appetite
Body is preparing for scarcity for food
A woman who drops from 200 to 130 lbs has to eat fewer calories to maintain that weight than a woman whose weight was steady at 130
Environmental/Societal Influences on weight
Portion size increases
Americans consume about 200 calories more per day than 30 years ago
Fast food items are 2-5x larger than in the 1980s
New editions of cookbooks have larger portions for same recipes – 43.7% increase in Joy of Cooking
Body Mass Index
a common way to talk about the range between underweight and obesity
Healthy range
18,5 - 24,9
Underweight
<18,5
Obese
30 - 34,9
weight and health
Overweight people (BMI 25-30) had LOWER mortality than people with BMIs of <25
Slightly obese people (BMIs < 35) did not have greater mortality than those with BMIs < 25
People with BMIs > 35 had higher mortality
Associations with obesity
Use of medical care, chance of developing Type 2 diabetes, high blood pressure, heart disease, stroke
Risk of migraine headaches, sleep apnea, colon cancer
Effective strategies for maintaining weight loss
Eating low calorie, low fat diet, eating breakfast (not low carb)
Exercise
Frequent self-monitoring
Low-carbohydrate diet
Atkins had more initial weight loss, but was no more effective at the end
Low-fat diet
Average of 1381 calories / day
Eat 4.87 times per day
Eat at fast food restaurants once per week and other restaurants 2.5 times per week
Greater avoidance of fried foods
78% eat breakfast every day
Anorexia
Emphasis on caloric restriction through low intake of foods or intake of only voluminous foods
Concern about nutrition facts, calories, ingredients, etc
Debilitating fear of weight gain
Going long periods of time without eating
Bulimia
episodes of binge eating followed by compulsive purging
Feelings of losing control, shame, disgust
Eating well past the signs of fullness
Binge Eating
Episodes of Binge Eating, typically no purging afterwards
Purging behaviors include vomiting, use of laxatives or diuretics, excessive exercise, fasting
Physical Signs of Vomiting: Callused hands, dental
Well-year
is a completely well year; void of ill-being or health-related problems
Health expectancy
the expected number of years a person is free from disability
Health disparity
African Americans and Native Americans have a shorter life and lower health expectancy than European Americans
Hispanics do not show poorer health rates as much as African Americans do
Asian Americans have lower infant mortality, longer life expectancy than other ethnic groups
34th
the US ranking in health expectancy
ethnic groups and health expectancy and life Expectancy
African Americans have a shorter life and lower health expectancy than European Americans
Native Americans also have a shorter life expectancy than European Americans
Overall, Hispanics do not show poorer health rates as much as African Americans do
Asian Americans have longest life expectancy and best health of any ethnic group in the US
challenges for health care
Helping older people achieve and maintain healthy and productive lifestyles and adjust to chronic illness diagnoses
Increasing diversity within the health care system to help reduce disparities
Factors that contribute to high costs
Expensive technology
Specialists
Administrative costs
Inappropriate treatments
Profit-oriented system
Primary prevention
avoids the development of a disease
Immunizations
Lifestyle changes
Diet
Exercise
Stress management
Alcohol and drug use
Risky behavior
Happiness and positive emotions
Secondary prevention
aims at early disease detection,
Regular physical exams and cancer screening
Cholesterol and blood pressure testing