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What makes up the central nervous system?
brain and spinal cord
What makes up the peripheral nervous system?
somatic and autonomic nervous system
What makes up the autonomic nervous system?
sympathetic and parasympathetic branch
Role of the brain (CNS)
issues orders to muscles, glands, organs, interprets information from senses
Role of the spinal cord (CNS)
body and brain communication, info from brain to muscles and glands, relays and regulates information
Role of somatic nervous system
transmit and receive messages e.g. visual and auditory
Spinal nerves
sensory info into spinal cord, motor commands out
Cranial nerves
carry info out brain (e.g. vision, taste etc.)
Sensory neurons
relay info to CNS (e.g. senses)
Motor neurons
info from CNS to other areas to control actions
Role of autonomic nervous system
involuntary actions such as heart beating and digestion, transmit and receive, maintain homeostasis
Sympathetic branch
increases activity for fight or flight response
Parasympathetic branch
decreases activity to stop fight or flight response
Role of the endocrine system
produces and secretes hormones e.g. pituitary gland, adrenal glands, testes and ovaries
What is the outer part of the adrenal glands?
adrenal cortex
What is the inner part of the adrenal glands?
adrenal medulla
What does the adrenal cortex produce?
cortisol (stress hormone)
aldostrene (maintenance)
What does the adrenal medulla produce?
adrenaline and noradrenaline
Ovaries explanation
- plays a role in female reproduction and egg production
- oestrogen and progesterone (post ovulation)
Testes explanation
- produces testosterone
- develops male features e.g. facial hair, growth spurts
Hypothalamus signals to PG how much testosterone needs to be produced. Signal is sent to the testes to produce testosterone
Short term fight or flight response (sympathetic adrenal medullary pathway) SAM
Hypothalamus detects stress. Activates the autonomic nervous system (sympathetic branch). Adrenal medulla activated and produces adrenaline. Causes a physiological reaction. Parasympathetic branch later activated to reduce symptoms and produce noradrenaline.
Long term fight or flight response (hypothalamic pituitary pathway) HPA
Hypothalamus stimulates CRF release which targets the pituitary gland. Pituitary gland produces ACTH which travels to adrenal cortex. Adrenal cortex produces cortisol which is converted to glucose.
Role of neurons
receive and transmit information to other cells
Relay neurons
signals between parts of CNS, connects motor and sensory
- found in brain, visual system and spinal cord

Synaptic transmission
Travels down neuron to post-synaptic terminal. Chemicals released as synaptic vesicles into synaptic fluid in synaptic cleft. Post synaptic receptor sites receive message and convert into electrical impulse. Remainder in synapse is reabsorbed.
Excitation and inhibition
Specific ion channels, causes potential in dendrites
Excitatory = dopamine
Inhibitory = serotonin
What is brain localisation?
theory of different areas of the brain responsible for different behaviours
Phineas Gage
1848, explosive ignited on railway to cause an explosive to pass through left cheek and eye (through frontal lobe). Survived but caused him from being calm to become quick tempered
Pons, midbrain, medulla oblongata
responsible for regulating basic functions such as heart and lungs
Frontal lobe
thinking, planning, etc.
emotions, behaviour and personality
Temporal lobe
memory, language and understanding
Parietal lobe
sense of world/perception, spelling
Occipital lobe
vision
Broca's area
speech reproduction (not nouns and verbs), can cause Broca's aphasia
Wernicke's cortex
understanding language, inability or damage can cause anomia
Motor cortex
muscles signals, through brain stem and spine (voluntary movement)
Pre-frontal cortex (part of motor cortex)
sensory information prior to movement
Pre-motor cortex (part of motor cortex)
plans movement
Somatosensory cortex
bodily sensations and touch
Left hemisphere of the brain
- smaller details
Broca and Wernicke, language processing
Right hemisphere of the brain
- overall patterns
emotional recognition, spatial awareness
Amygdala
social, sexual behaviour
Thalamus
motor and sensory (cerebral cortex)
Hypothalamus
controls body systems (endocrine, homeostasis)
Hippocampus
short term memory
Cerebellum
movement, time, emotion, some learning and memory
Brain stem
information communicated between body and higher brain
Localisation of neurological disorders (brain localisation eval)
removal of areas of the frontal lobe (in severe cases of OCD and depression) controls behavioural aspects
- may have caused some aggressive behaviours
Brain plasticity definition
the ability for brain structure and neurological paths to change throughout your life
there is rapid growth in synaptic connections during infancy
How does brain trauma cause the brain to develop?
reorganises itself by forming new synaptic connections
- secondary neural pathways enables functions to occur in same way as before
Reforming blood vessels (brain plasticity)
occurs during brain plasticity
Increased brain stimulation (brain plasticity)
Takatsuru - if undamaged hemisphere is stimulated recovery from a stroke can be improved
Recruitment of homologous (brain plasticity)
areas on the opposite side of brain perform specific tasks. may cause functionality to shift back in time
Axonal sprouting (brain plasticity)
damaged with neighbouring neuron, may sprout connections to replace old ones
Denervation supersensitivity (brain plasticity)
axons that do a similar job become aroused to a higher level, over sensitivity may cause pain
Practical application (brain plasticity eval)
neurorehabiliation may be needed to maintain improvements, may require further intervention to completely successful
recovery tends to slow down after a few weeks
Medina (brain plasticity eval)
prolonged drug use means poorer cognitive functions and increased chance of dementia
- amputees may develop phantom limb syndrome sensation in missing limb due to reorganisation in somatosensory cortex
Age and plasticity (brain plasticity eval)
plasticity tends to reduce with age, better prosperity for reorganisation during childhood as consistent adaptation in brain
Synaptic pruning
disused connections deleted, used connections strengthened
Event related potentials
EEG statistical analysis, averaging technique, ERPS filtered out leaving responses relating to
Event related potentials strengths
describes precise roles of these cognitive processes
Event related potentials weaknesses
standardisation between different studies, background noise and extraneous variables may effect analysis of results
EEG (electroencephalogram)
electrodes attached to cap to record electrical impulses produced by brain activity (diagnoses certain conditions)
EEG strengths
invaluable for diagnoses such as epilepsy as easily detectable, high resolution, understanding stages of sleep
EEG weaknesses
cannot pinpoint exact source of neural activity or distinguish between activities
Post mortem examinations
analysis after death to examine linked abnormalities, may compare with neurological brain to assess extent
Post mortem examinations weaknesses
ethical issues, may be related to unrelated trauma or decay
Post mortem examinations strengths
understanding of key processes (Broca and Wernicke)
Functional magnetic resonance imaging (fMRI)
MRI technology used to measure brain activity
- detection of oxygen levels in brain, 3 dimensional images produced
Functional magnetic resonance imaging (fMRI) strengths
risk free, non-invasive, straightforward, high resolution
Functional magnetic resonance imaging (fMRI) weaknesses
expensive, can be unclear, may be difficult to tell what kind of brain activity is represented
What is a split brain?
a condition caused by removing the corpus collosum - it is cut to contain epilepsy into one hemisphere of the brain to reduce fits
What is hemispheric lateralisation/contra-lateralisation?
right hemisphere controls the left side, left hemisphere controls the right side
What are biological rhythms?
periods during of biological and physiological processes e.g. growth, temperature, appetite, menstrual cycle
Ultradian rhythms
shorter than 24 hours
What is REM sleep? (ultradian rhythms)
rapid eye movement
- characterised by being muscles being paralysed to not act out dreams, increased heart rate and brainwaves
What is stage 1 of sleep?
falling asleep, reaching a hypnogogic state, desynchronised brain waves
What is stage 2 of sleep?
light sleep, aware of surroundings, senses still activated, easily woken, sleep spindles (surge of electrical activity), k-complexes (electrical activity due to environmental stimuli) occur
What is stage 3/4 of sleep?
deep sleep, no senses, difficult to wake up, synchronised brain waves
How is brain activity measured?
electrical brain activity (EEG)
eye movement (EOG)
muscle movement (EMG)
Sleep cycle process
stage 1, stage 2, stage 3, stage 4, stage 3, stage 2, REM, stage 2, cycle repeats, occurs every 90 minutes
What is an infradian cycle?
longer than 24 hours e.g. menstrual cycle
Menstrual cycle as an infradian cycle
28 days, studies involve pheremones and synchronisation
4-5 before bleeding, 68% of females experiences change
may be controlled my exogenous zeitgebers
SAD as an infradian cycle
SAD (seasonal affective disorder), more melatonin is released during the day due to less light, causing more depressive symptoms
Exogenous zeitgebers
external environmental cues, such as light, dark, temperature, seasons
Endogenous pacemakers
internal body clock
Relationship between EPs and EZs
light receptors located in eye take in light
optic nerve to hypothalamus
SCN (internal body clock) to pineal gland
pineal gland secretes serotonin for as long as light is taken in
melatonin produced in dark hours
What are circadian rhythms?
every 24 hours such as sleep wake cycle
Shift work (disruption to bio-rhythms)
listed in the international classification of sleep disorders
sleep during the day can cause disruption to social activities, sunlight and noise
electric light changed society as we can now rely on electricity instead of natural light and dark patterns
average sleep time has decreased by 1.5hrs
body prepares us for sleep between 2am and 4am - accidents can occur during night shift work at these hours such as Chernobyl
Jetlag (disruption to bio-rhythms)
caused when there is a dislocation between our body clock and local zeitgebers
can cause extreme tiredness, depression, slowed mental and physical reactions
phase delay = delaying our cycle
phase advance = advance our cycle
frequently worse when travelling west to east