Week 1 - Molecule of Life
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16 Terms
Griffith - Process
Live S - dies
Live R - lives
Heat killed S - lives
Heat killed S + live R - dies + live S inside
Griffith - Pneumococci
Rough - avirulent
Smooth - virulent + sugar coat
Griffith - Findings
Transfer code for protective sugar coat
Bacteria change physical traits
Avery et al. - Findings
Separate cell components using enzymes
DNA transfer virulence - not proteins/RNA
Hershey & Chase - Process
Mix T2 bacteriophage with E coli
Centrifuge
32P DNA - radioactivity in host
35S Protein - radioactivity in phage ghosts
Hershey & Chase - Findings
DNA genetic material - NOT protein
Watson & Crick - 2 Evidence
X ray diffraction
Chargraffs rules
Purine
Larger
Double ring
A + G
Pyrimidine
Smaller
Single ring
C + T + U
Nucleoside
Base + sugar
Histone Octamer - Bead
8 proteins
Nucleosome
8 histone proteins + DNA
Genome Map - 2
Genetic
Physical
Genetic Map
Relative order/distance of genes based on recombination frequency
Physical Map
Actual nucleotide distances
Linkage Group
Genes close together on same chromosome likely inherited together (crossing over)