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Gregor Mendel
the father of modern genetics; an Austrian monk who studied pea plants to understand how traits are inherited
true-breeding
organisms that always pass down the same traits to offspring when self-pollinated
P generation
the parent generation; two true-breeding plants with contrasting traits
F1 generation
the first generation of offspring from the P generation; all are hybrids
F2 generation
the second generation from self-fertilized F1 hybrids; shows a 3:1 trait ratio
gene
a segment of DNA that codes for a specific trait
allele
an alternative form of a gene found at the same locus on homologous chromosomes
principle of dominance
one allele can mask the effect of another; dominant hides recessive
principle of segregation
alleles separate during gamete formation and reunite randomly at fertilization
genotype
the genetic makeup of an organism (e.g., Aa, BB)
phenotype
the observable physical traits of an organism (e.g., blue eyes)
homozygous
having two of the same alleles for a gene (e.g., TT or tt)
heterozygous
having two different alleles for a gene (e.g., Tt)
punnett square
a diagram used to predict the outcome of a genetic cross
monohybrid cross
a cross that follows a single trait with two variations(e.g., Tt vs tt).
principle of independent assortment
alleles of different genes assort independently during gamete formation
dihybrid cross
a genetic cross that follows two traits; F2 ratio is 9:3:3:1
probability
the likelihood that a specific genetic event will occur
rule of addition
used to calculate the probability of either of two mutually exclusive events
rule of multipluication
used to calculate the probability of two independent events both occurring
testcross
a cross between an individual with an unknown genotype and a homozygous recessive to determine the unknown genotype
phenotypic plasticity
when the same genotype can result in different phenotypes due to environmental conditions
polygenic inheritance
traits controlled by multiple genes, showing continuous variation (e.g., skin color)
pleiotropy
a single gene affects more than one trait
multiple alleles
a gene with more than two possible alleles (e.g., blood type alleles: A, B, O)
incomplete dominance
the heterozygous phenotype is a blend of the two homozygous phenotypes (e.g., wavy hair)
codominance
both alleles in a heterozygote are fully expressed without blending (e.g., AB blood type)
epistasis
one gene affects or masks the expression of another gene
ABO blood group system
an example of codominance and multiple alleles; determines blood type
genotype dictates phenotype
genes (DNA) determine proteins, which in turn influence the organism’s traits and functions