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what is the Aphasia top 10
basic facts
“classic types”/ W-L model
spontaneous recovery/plateau myth
neuroplasticity
not a loss of language
does aphasia therapy work
functional/compensatory, restorative/impairment-based interventions
interactive activation model
FRAME supportive communication strategies
is there a lot of community knowledge of aphasia?
no— in fact about 85% haven’t heard of it
how many americans does aphasia affect?
approximately 2 million (180,00 acquire every year)
Aphasia is more common than …
Parkinson’s
what is aphasia?
an acquired selective impairment of language modalities resulting from focal lesion in language dominant hemisphere
a linguistic performance disorder, processing disorder
is aphasia a disorder of linguistic knowledge?
no
(chronic) aphasia’s onset is …?
sudden
what is the most common etiology of aphasia?
stroke (20-40% result in aphasia)
what is primary progressive aphasia (PPA)?
a gradual onset, related to mild cognitive impairment/dementia
word finding difficulties, object naming difficulties, word comprehension impairments in spontaneous convo or on formal language measures
does aphasia only involve one language modality?
no it involves multiple
aphasia results from damage to the … which means it may co-exist with motor, cognitive, or sensory impairment(s)
CNS
what is aphasia NOT?
MSD
loss of language
loss of intelligence
dementia (with the exception of PPA)
psychological/psychiatric impairment
what are the brain basis of stroke outcomes?
size and location of lesion and “spared tissue”
factors contributing to biological resilience
changes related to recovery (bio and behavior driven)
experience-dependent neuroplasticity is possible for how long?
across the lifespan, extends beyond the spontaneous recovery period for years
evidence to site that aphasia therapy works
Robey 1994
Robey 1998
Holland, Fromm, DeRuyter, Stein 1996
Brady, Kelly, Godwin, Enderbery, & Campbell June, 1, 1996
WHO international classification of functioning, disability, and health (ICF)
how does impairment affect body structures, body functions, activities and participation, contextual factors
allows for holistic service delivery
what is the purpose of treatment according to the biopsycholsocial approach
improve language, communication, quality of life
take biological-impairment based factors, psycholinguistics, and cognitive processes within social context
what are the two types of treatment?
impairment-based or restorative
compensatory or functional communication
what is the target and goal for impairment-based or restorative treatment?
target: specific language impairment
goal: generalization to new items and environments
reducing impairment > improving success of communication
what is the target and goal for compensatory or functional communication treatment?
target: individual communication abilities with relevance —> eliminating barriers
goal: improving successful communication and quality of life
quality of life > reducing impairment
what does impairment-based treatment requires knowledge of?
models of aphasia in order to help interpret assessment and treatment plans
What are the modular models/theories?
language is stored in whole parts in specific locations
processed/put together unit by unit step by step
what are the distributed models (aka connectionist)?
many tiny language units put together via activation in the moment
processed simultaneously (not sequentially)
what does the Wernicke-Lichtheim model try to show?
where the lesion is and what theoretically happens
aka the house
is a PWA his/her impairment?
NO —> they have unique abilities, needs, goals, strengths, personal identities, attitudes, quality participation
what is EBP?
best available external evidence, clinical expertise, and patient preferences/values
aphasia is a … disorder that causes a variety of impairments that cannot be explained by dementia, sensory loss, motor issues
multimodality
what is the aphasia continuum?
anyone can appear like they have aphasia given the right factors
everyone can present differently
what are the main linguistic features of aphasia?
anomia
circumlocution
agrammatism/telegraphic speech
auitory comprehension
phonological errors
phonemic paraphasias
semantic errors
semantic/verbal paraphasias
perseverations
neologisms/jargon
stereotypy
alexia
agraphia
what is one of the main ways aphasia is described?
fluent/non-fleunt dichotomy
the Wernicke-Lichtheim has … parameters that leads to … types
4, 8
parameters of the wernicke-lichtheim model
fluency
auditory comprehension
repetition
naming
how is fluency multidimensional?
can de defined by length, pauses, prosody, rate, effort, intonation, and/or elaboration
what are the 8 classic aphasia types (w-l model)?
Broca’s: NF
Wernicke’s: F
Conduction: F
Transcortical Motor: NF
Transcortical Sensory: F
Mixed Transcortical: NF
Global: NF
Anomic: F
should you always describe apahsia using the types?
no, it is best that you attend to features and describe the deficits instead of attending to labels
why are the classic types classification still useful, even though not as clinically useful now?
many medical professionals and clinicians use this to describe
starting point to understand the patient
is there a 1 to 1 correlation with the language symptoms/types of aphasia and the site of lesion?
no
do people always have a classified aphasia?
many have “unclassified”
if classified, may no longer be accurate or reflect current abilities/deficits
does language processing only rest on Broca’s and Wernicke’s areas?
no language processing is a network which is unique and overlapping
large scale language architecture
what should you always follow when addressing aphasia?
a descriptive, deficit-based assessment and treatment approach
what are the main classification systems for aphasia?
fluent/nonfluent
wernicke-lichtheim model
does fluency provide sufficient information alone?
no, it is a bit relative actually
when you describe aphasia through linguistic impairment features, it leads to ….
a more specified description of the impairment that is helpful for all aspects of clinical decision making
what is preferred to identify and describe impairment and abilities
linguistic features/errors
what is the hallmark of aphasia (all types)?
anomia
what is anomia?
a word finding difficulty
what is circumlocution?
description of the target
what is agrammatism/telegraphic speech?
omission of function words, content words used only
what are phonemic paraphasias?
phonological errors (substitutions, additions, anticipatory, perseverative) that are less than 50% of all the phonemes in the target word
what are semantic/verbal paraphasias?
semantically related errors
what are semantic errors?
an unrelated real word is produced
what are mixed paraphasias?
both phonological and semantic
what is a neologism?
nonword (over 50% of phonemes in target are errored)
what is jargon?
utterance comprised of neologisms
what are perseverations?
recurring responses (usually a response produced eralier)
what is stereotypy?
a frequently used word/phrase in place of a target
what doe most people with aphasia have?
alexia and agraphia
what is agraphia?
writing impairment
what is alexia?
reading impairment
will people with aphasia only have one type of error?
no, typically have a mix and typically requires many trials/assessments to see this
which lobes are most important for speech and language?
frontal and temporal
where is the insula?
if you part the sylvian fissure, it is between the frontal and temporal lobes
what does the insula do?
self-awareness
consciousness
cognitive functions
motor planning and control
Wernicke-Lichtheim house diagram
early neuroanatomically based model of language and its impairment
what is the most common/general aphasia type?
Broca’s
is Broca’s fluent or nonfluent?
nonfluent
speech behavior seen in Broca’s aphasia
anomia
short phrase length
agrammatism
phonemic paraphasias
intact comprehension
impaired repetition
writing may also be impaired
what is Broca’s aphasia also known as?
expressive aphasia
where is damage associated with Broca’s aphasia?
left inferior frontal gyrus (IFG) aka Broca’s area
BA 44, 45
what are some associated signs with Broca’s aphasia?
right hemiparesis/hemiplegia
right hemisensory loss
what vascular distribution is associated with Broca’s aphasia?
anterior branches of the MCA
if someone has a lesion in the left IFG, does that always mean they present with Broca’s aphasia?
no, they may have lesion in another area and present with Broca’s or present with another type of lesion is in left IFG
which aphasia most commonly co-occurs with apraxia of speech (AOS)?
Broca’s-like
what is apraxia of speech?
an impairment of articulation and prosody
deficit in motor planning
what is AOS not?
an impairment of language or musculature
sequence of motor movements
motor planning → motor programming → execution
what are the 3 necessary features for diagnosing apraxia of speech?
sound errors, especially distortions and distorted substitutions
slowed rate
prosodic abnormalities
slowed rate characteristics AOS
slowed interval between words, syllables to produce sounds, and/or sound transitions
prosodic abnormalities in AOS
syllable segregation and equalized stressed
what are non-discriminatory characteristics of AOS and therefore cannot be used to base diagnosis off of?
articulatory groping
increasing error with increasing word length
phonemic substituions
cluster reduction
speech initiation difficulties
awareness of errors → self-correction
automatic speech > propositional speech
islands of error free speech
what are characteristics that can NOT be used to diagnose apraxia of speech?
limb or oral apraxia
expressive-receptive speech/language gap
what are the exclusionary characteristics for AOS?
fast rate, normal rate, normal prosody
is wernicke’s aphasia fluent or nonfluent?
fluent
what are notable speech behaviors seen in wernicke’s aphasia?
empty speech
press of speech (rapid)
notable anomia
jargon with neologisms and verbal paraphasias
not always aware of deficits/errors
reading is often quite challenging
impaired auditory comprehension and repetition
what is wernicke’s aphasia also known as?
receptive aphasia
where is damage associated with wernicke’s aphasia?
left superior temporal gyrus aka primary auditory cortex
BA 22, may involve 39, 40
what are some associated signs with wernicke’s aphasia?
possible right hemianopia
what is the vascular distribution associated with wernicke’s aphasia?
MCA and PCA
is werncike’s as common as broca’s like?
no
what would some spared tissue in wernicke’s area potentially resolve into? (what kind of aphasia)
conduction or anomic
is conduction aphasia fluent or nonfluent?
fluent
what are the notable speech behaviors of conduction aphasia?
anomia
speech may be interrupted by word-finding pauses or attempts to self-correct
difficulty with repetition (conduit d’approache= closer, conduit d’ecart= farther)
aware of deficits
good auditory comprehension
where is damage associated with conduction aphasia?
arcuate fasciculus
may extend to areas such as inferior parietal region, supramarginal gyrus (BA 40) with or without extension to subcortical areas, the insula, left primary auditory cortices, or underlying white matter
what are some associated signs with conduction aphasia?
right hemiparesis
right hemisensory loss
right hemianopia
what is the vascular distribution associated with conduction aphasia?
MCA, parietal branches of PCA
lesion information is only …..
a hint/starting place
the descriptive approach to classifying aphasia is…
more informative
is the wernicke-lichteim model the best to use?
no, it is a good starting point and some terminology is still used
what is the most detrimental/profound aphasia?
global
what are defining characteristics of global aphasia?
profound anomia
little to no verbal output
poor external auditory comprehension
stereotypy (do not fit context)
can affect all language modalities (tho maybe not all equally)