CPJE Brand/Generics

Chlorothiazide

Diuril (TD: 500 mg)

HCTZ (2)

Microzide, Hydrodiuril (TD: 50 mg)

HCTZ + TM (2)

Dyazide, Maxzide

Chlorthalidone

Thalidone (TD: 25 mg)

Metolazone

Zaroxolyn (ok if renal dysx(x) TD: 20 mg)

Indapamide

Lozol (TD: 2.5 mg)

Furosemide (2)

Lasix, Furosix (TD: 40 mg BID)

Torsemide

Demadex, Soaanz (TD: 10 mg QD)

Bumetanide

Bumex (TD: 1 mg BID)

Ethacrynic Acid

Edecrin (TD: 25 - 50 mg)

Triamterene

Dyrenium (TD: 300 mg)

Amiloride

Midamor (TD: 20 mg)

Spironolactone (2)

Aldactone, Carospir (susp) (TD: 25 - 50 mg)

Eplerenon

Inspra (TD: 25 - 50 mg)

Captopril

Capoten (TD: 50 mg TID)

Enalapril IV

Enalaprilat

Lisinopril + HCTZ (2)

Prinzide, Zestorectic

Moexipril

Univasc (TD: 30 mg)

Tandolapril

Mavik (TD: 4 mg)

Azilsartan

Edarbi (TD: 80 mg) (keep in orig container to protect against light and moisture)

Aliskiren

Tekturna (TD: 300 mg)

Metoprolol succinate (2)

Toprol XL, Kapspargo Sprinkle (apple sauce, pudding) (HTN 400 mg/day) (HF 200 mg/day)

Esmolol

Brevibloc (for HTN emergency)

Propranolol (3)

Hemangeol, Inderal, InnoPran XL (IR 80 mg BID; ER are QD)

Timolol

Timoptic, Betimol (TD: 40 mg BID)

Sotalol (3)

Betaspace, Sorine, Sotylize (TD: 320 mg)

Carvedilol

Coreg (IR: 50 BID, ER: 80 mg QD (3.125 - 6.25 - 12.5 - 25 mg tbs))

Verapamil (4)

Calan, Isoptin, Verelan, Covera (TD: 120 mg/day, QD-BID-TID)

Amlodipine Combo

• + benazepril = Lotrel

• + valsartan = Exforge

• + olmesartan = Azor

Mono: Katerzia oral supp, Norvasc

TD: 10 mg

Felodipine ER

Plendil (TD: 10 mg)

Isradipine CR

DynaCirc (TD: 10 mg)

Nicardipine

Cardene (TD: 60 mg BID or TID)

Nifedipine ER (2)

Adalat CC, Procardia XL (TD: 90 mg)

Nisoldipine

Suldar (TD: 34 mg)

Clevidipine

(avoid in soy + egg allergy)

Doxazosin

Cardura

Hypertension 16mg hs

benign prostatic hyperplasia (BPH) 8mg hs

Terazosin

Hytrin

Hypertension max 20mg hs

benign prostatic hyperplasia (BPH) 10mg hs

Prazosin

Minipress

Hypertension 5mg bid-tid

benign prostatic hyperplasia (BPH) 2mg BID

Tamsulosin

Flomax

Benign prostatic hyperplasia (BPH) 0.4mg qd

Alfuzosin

Uroxatral

Benign prostatic hyperplasia (BPH) 10mg qd

Clonidine

Catapres - 0.1-0.3mg BID

Catapres TTS-1, 2, 3 0.1, 0.2, 0.3mg/24 hr/week

Methyldopa

500mg BID (max 3000mg/d!)

S.E.: lupus like symptoms, hepatitis, myocarditis, hemolytic anemia

Hydralazine

Apresoline 75mg QID, 20mg/ml inj. S.E.: lupus like symptom

TRIbenzor

olmesartan, amlodipine, HCTZ

Exforge HCT

amlodipine, valsartan, HCTZ

IV agent Hypertensive Crisis

1. Hydralazine

2. Nitroglycerin

3. Labetalol

4. Esmolol

5. Enalaprilat

6. Clonidine

7. Phentolamine

8. Nitroprusside (Nipride)

9. Nicardipine

Fluvastatin

Lescol, Lescol XL

Lovastatin (2)

Mevacor IR, Altoprev ER

Pitavastatin (2)

Livalo, Zypitamig

Simvastatin (+combo)

Flolipid, Zocor

(+ ezetemibe = Vytorin)

Pravastatin

Pravachol

Atorvastatin

Atorlaiq

Lomitapide

Capsule: Juxtapid (Homozygous familial hypercholesterolemia (HoFH)

evinacumab-dgnb

IV: Evkeeza (Homozygous familial hypercholesterolemia (HoFH)

Bempedoic acid (+ combo)

Nexletol

(+ ezetimibe = Nexlizet)

Cholestyramine

Questran, Prevalite (tooth discoloration), LoCholest

Colestipol

Colestid (16 GRAM tab or 30 GRAM powder)

Bile-acid Binding RESINS

Contraindicated if biliary obstruction or high TGs >300

Colesevelam

Welchol (preferred in preggers)

Fenofibrate

Tricor, Trilipix, triglide, Lipofen, Antara

(Fibrates: CI if liver, renal + gallbadder disease)

Alirocumab

Praluent (increase LFTs) (TD: 75-150 mg q2weeks SC or 300 mg q 4weeks)

Evolocumab

Repatha (140 mg q2x OR 420mg q4wks SC)

Inclisiran (Leqvio)

(has to be done in clinic)

284 mg SC x1, at 3 mo, then q6 mo

Celexa

40 mg/d max (QT risk)

Lexapro

10-20 mg / day

Fluoxetine for PMDD

Sarafem

zuranolone

Zurzuvae (postpartum depression - CIV)

ALL SSRIs, we have to monitor Na+, but why?

SIADH

Paroxetine for menopause and PMDD

Brisdelle

Duloxetine

Cymbalta, Drizalma Sprinkle

Vortioxetine

Trintellix

Venlafaxine

Effexor

Desvenlafaxine

Pristiq

Vilazodone

Viibryd (WITH FOOD)

Buproprion

IR tab → 100 mg TID

SR tab → 150 mg BID

XL → 450 mg QD

Max (seizure risk?): 450 mg

TCAs (3rd line for depression)

2ary Amines

• Nortriptyline (Pamelor) 10mg BID

• Desipramine (Norpramin) 25mg BID

• Amoxapine 50mg BID

3ary Amines- More anticholinergic effects and sedation

• Amitriptyline (Elavil) 25mg BID. Off-label for pain and migraines

• Imipramine (Tofranil) 25mg BID

• Doxepin (Sinequan, Silenor: for insomnia) 300mg hs

S.E.: Cardiotoxic, anticholinergic S.E., vivid dreams, wt gain, sedation, falls, hypotension, risk overdose 1-2 g can be lethal

MAOIs (3rd line for depression)

Anticholinergic S.E.; orthostasis; sedation (except tranylcypromine); sexual dysfunction; weight gain;

• Phenelzine (Nardil)

• Isocarboxazid (Marplan)

• Tranylcypromine (Parnate)

• Selegiline TD

  • (Emsam 12mg/24hr patch → PD

  • Changed daily. Upper chest, back, upper thigh, upper arm

  • Eldepryl (cap)→ Parkinson)

  • Zelapar (ODT) → Parkinson.

• St. John’s Wort

Trazodone

Desyrel

Used primarily for sleep (very sedative) 100mg hs. Caution: sexual dysfunction, priapism

Esketamine

Spravato (spray - CIII) (for tx-resistant depression)

Brexanolone

Zulresso (IV inject - for postpartum depression)

Hydroxyzine (other option for anxiety)

Vistaril, Atarax (anxiety + allergies)

2nd line for anxiety

• Gabapentin

• Pregab

• Propranolol

• Buspirone (Buspar)

  • no ACH effects (tolerated by eldery)

  • not sedative

Shortterm Benzos for anxiety

Safer in elderly/liver dys: LOTe

• ox = Serax

• Tem = Restoril

others: alprazolam, Triazolam (Halcion), Midazolam (Versed)

Long term Benzos for anxiety (tapering off benzo)

Diazepam (Valium) 2-10mg prn- for alcohol withdrawal, spasm

Clonazepam (Klonopin) 0.125-2mg prn- for seizures

Clorazepate 3.75-15mg prn- for seizures

Chlordiazepoxide (Librium) 5-25mg prn- for alcohol withdrawal

Flurazepam (Dalmane) 15-30mg qhs for insomnia