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A comprehensive set of vocabulary flashcards covering DNA, transcription/translation, organelles (membrane-bound and non-membrane-bound), cell transport, cell physiology, body planes, serous membranes, body cavities, and basic anatomy/ physiology concepts.
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Role of DNA
Stores genetic information and directs cellular activities by guiding protein synthesis.
What percentage of DNA codes for genes
Only a small portion; about 1-2% of DNA consists of genes.
Start codon
AUG; signals initiation of translation and codes for methionine.
Stop codons
UAA, UAG, UGA; terminate translation and do not code for amino acids.
Transcription
DNA is copied into RNA (mRNA) in the nucleus; prepares for protein synthesis.
Translation
mRNA is decoded by ribosomes to synthesize a polypeptide (protein) in the cytoplasm.
Final product of transcription
mRNA transcript of the gene.
Final product of translation
Polypeptide chain (protein) produced from mRNA.
DNA base pairing rules
A pairs with T; C pairs with G.
RNA base pairing to DNA
A-U, T-A, C-G, G-C (RNA uses uracil instead of thymine).
Chromosomes
Condensed DNA-protein structures visible during cell division.
Chromatin
Looser DNA-protein complex present most of the cell cycle; allows gene expression.
Nucleus (organelle)
Membrane-bound organelle that houses DNA and controls cell activities.
Mitochondria
ATP production (cellular respiration); energy powerhouse of the cell.
Rough endoplasmic reticulum
ER with ribosomes; synthesizes and processes proteins.
Smooth endoplasmic reticulum
ER without ribosomes; lipid synthesis and detoxification.
Golgi apparatus
Modifies, sorts, and packages proteins for secretion or delivery.
Lysosome
Contains digestive enzymes that break down waste materials.
Peroxisome
Breaks down fatty acids; detoxification; contains enzymes like catalase.
Vesicle
Small membrane-bound sac for transport within or outside the cell.
Chloroplast
Site of photosynthesis in plants; contains chlorophyll.
Vacuole
Storage sac; large central vacuole in plants maintains turgor.
Ribosome (non-membrane bound)
Site of protein synthesis; not surrounded by a membrane.
Cytoskeleton
Filaments that give cell shape, support, and enable movement.
Centrosome/Centrioles
Organizes spindle fibers during cell division.
Proteasome
Degrades unwanted or damaged proteins.
Cilia
Short, numerous projections that move substances along cell surfaces.
Flagella
Long, whip-like projections used for cell locomotion.
Microvilli
Finger-like extensions that increase surface area for absorption.
Diffusion
Movement of particles from high to low concentration until equilibrium.
Facilitated diffusion
Passive transport via membrane proteins down a concentration gradient.
Osmosis
Diffusion of water across a semipermeable membrane toward higher solute concentration.
Active transport
Energy-requiring transport moving substances against their gradient.
Primary active transport
Direct use of ATP to move substances against their gradient (e.g., Na+/K+ pump).
Secondary active transport
Uses ion gradients created by primary transport to move other substances (co-transport or antiport).
Vesicular transport
Transport of substances via vesicles (endocytosis and exocytosis).
Isotonic solution
Solute concentration equal to cell interior; no net water movement.
Hypertonic solution
Higher solute outside than inside; water moves out; cell shrinks.
Hypotonic solution
Lower solute outside than inside; water moves in; cell swells.
Resting membrane potential (RMP)
Electrical potential difference across the plasma membrane when the cell is at rest.
Two ions important to RMP
Sodium (Na+) and Potassium (K+); gradients maintained by the Na+/K+ pump.
Sodium-potassium pump
Na+/K+-ATPase: pumps 3 Na+ out and 2 K+ in against gradients; uses ATP.
Passive transport processes
Movement across the membrane without energy: diffusion, facilitated diffusion, osmosis.
Active transport processes
Energy-requiring transport: primary, secondary, and vesicular transport.
Structural units of organisms from smallest to largest
Atoms → Molecules → Organelles → Cells → Tissues → Organs → Organ systems → Organism.
Metabolism
Sum of all chemical reactions in the body.
Catabolism
Breakdown of larger molecules into smaller ones; releases energy.
Anabolism
Building up of complex molecules from smaller ones; requires energy.
Anatomy vs Physiology
Anatomy studies structure; physiology studies function; both explain the same body part differently.
Directional terms (opposites)
Anterior vs Posterior; Superior vs Inferior; Medial vs Lateral; Proximal vs Distal; Superficial vs Deep.
Five planes of the body
Sagittal (left-right), Midsagittal/Median (equal left and right), Frontal/Coronal (anterior/posterior), Transverse/Horizontal (superior/inferior), Oblique (angled plane).
Serous membrane that lines body cavities
Parietal serosa lines the cavity walls.
Serous membrane that covers organs
Visceral serosa covers the organs within cavities.
Function and location of serous fluid
Lubricates membranes to reduce friction; located between parietal and visceral layers in serous cavities.
Body cavities (two large divisions)
Dorsal (cranial and spinal) and Ventral (thoracic and abdominopelvic).
Major organs in dorsal cavity parts
Cranial cavity: brain; Vertebral (spinal) cavity: spinal cord.
Major organs in ventral cavity parts
Thoracic cavity: heart and lungs (pleural and pericardial). Abdominopelvic cavity: digestive organs, liver, bladder, reproductive organs.
Body part terminology (memory aid)
Terms used to describe location and direction on the body; memorize via flashcards or mnemonics.