2. dog - core vaccines

canine core vaccines

1. rabies

2. distemper (CDV)

3. parvovirus (CPV)

4. adenovirus-2 (CAV-2)

5. parainfluenza (CPi2)

6. leptospira

puppy vaccination summary

• < _____ weeks

• _____ dose(s) of a modified live virus (_____) for:

  • _____

  • _____

  • _____

  is recommended every _____ weeks from _____ weeks of age

• the final booster should be administered no sooner than _____ weeks of age

1. 16

2. 1

3. attenuated

4. parvovirus (CPV)

5. distemper (CDV)

6. adenovirus-2 (CAV-2)

7. 3-4

8. 6-8

9. 16

older dog vaccination summary

• dogs over _____ weeks of age

• _____ dose(s) of a modified live virus (_____) for:

  • _____

  • _____

  • _____

  given _____ weeks apart

• booster given between _____ months with revaccination every _____ years

1. 16

2. 2

3. attenuated

4. parvovirus (CPV)

5. distemper (CDV)

6. adenovirus-2 (CAV-2)

7. 3-4

8. 6-12

9. 3

canine parvovirus (CPV): a _____ contagious virus that causes acute, infectious _____ illness in young dogs

• is resistant to _____, _____, _____, & _____

  • it can survive in the environment for _____ periods of time

• infected dogs must be _____

1. highly

2. gastrointestinal (GI)

3. heat

4. cold

5. humidity

6. drying

7. long

8. isolated

breeds with an increased risk of canine parvovirus (CPV)

• _____

• _____ _____

• american _____ _____

• english _____ _____

• _____ _____

1. rottweilers

2. doberman pinschers

3. pitbull terriers

4. springer spaniels

5. german shephard

puppies born to a dam with sufficient _____ _____ (CPV-AB’s) in their colostrum are protected for the first few _____ of life

susceptibility increases as _____ _____ _____ (MDA) wanes

1. parvovirus antibodies

2. weeks

3. maternal derived antibodies

canine parvovirus (CPV) is shed in _____ of infected dogs within _____ days of exposure

1. feces

2. 4-5

how does canine parvovirus (CPV) spread?

1. dog-to-dog contact

2. contaminated stool

3. environment - surfaces

4. people - clothes

canine parvovirus (CPV) target

• viral replication initially occurs in the _____ _____ tissue causing _____ _____ (spread of pathogens through the bloodstream)

• targets the rapidly dividing cells in the _____-_____ _____ epithelium, _____ tissue, & _____ _____

  • causes _____ _____ (death of epithelial cells) & _____ _____ (flattening of intestinal cells)

  • impaired _____ capacity → disrupted _____ _____ function

1. oropharynx lymphoid

2. hematogenous dissemination

3. small-intestinal crypt

4. lymphopoietic

5. bone marrow

6. epithelial necrosis

7. villous atrophy

8. absorptive

9. gut barrier

what are the symptoms of canine parvovirus (CPV)?

1. lethargy

2. loss of appetite

3. fever

4. vomiting - dehydration

5. sever, blood, smelling diarrhea - dehydration

pups infected with canine parvovirus (CPV) in utero or <_____ weeks old or to an _____ dam that lacks the naturally occurring _____, can result in _____ _____, _____, & _____ (inflammation of the heart muscle) → heart failure

1. 8

2. unvaccinated

3. antibodies

4. myocardial infection

5. necrosis

6. myocarditis

a false negative for canine parvovirus (CPV) can be due to it being _____ in the course of the disease or due to the _____ _____ of large volume of feces or after the rapid decline in _____ _____

1. early

2. dilution effect

3. viral shedding

animals infected with the parvovirus can be infectious for at least _____ _____ in contaminated spaces

thorough _____ is necessary before admitting new animals

1. 1 year

2. disinfection

canine distemper (CDV): _____ contagious virus that causes _____ & _____ issues

1. highly

2. respiratory

3. gastrointestinal

canine distemper (CDV) is sensitive to _____ _____, most _____, & is relatively _____ outside the host

1. lipid solvents

2. disinfectants

3. unstable

canine distemper (CDV) is shed through _____ _____ _____ & can be shed for several _____

1. all body secretions

2. months

how does canine distemper (CDV) spread?

1. direct contact

2. aerosol

3. respiratory droplets

canine distemper (CDV) target

• virus initially replicates in the _____ tissue of the _____ tract causing _____ (presence of a virus in the bloodstream)

  • then infects all _____ tissues: respiratory, GI, urogenital, epithelium, CNS, & optic nerves

  • the degree of _____ depends on the level of humoral immunity in the host (_____)

• _____ _____ (patter of fever where there are two peaks in temperature)

• _____ (low WBC count)

• GI & respiratory _____ (mucous buildup)

1. lymphatic

2. respiratory

3. viremia

4. lymphatic

5. viremia

6. antibodies

7. diphasic fever

8. leukopenia

9. catarrh

what species are susceptible to canine distemper (CDV)?

1. canidae

2. mustelidae (ferret, skunk)

3. raccoon

4. red panda

5. bear

6. asian elephant

7. japanese monkey

8. large felidae

what is the most common sign of canine distemper (CDV)?

1. green nasal & ocular discharge

2. loss of appetite

3. depression

pathological features of canine distemper (CDV)

• _____ _____: inflammation/scarring of the spaces between the lungs’ air sacs

  • acute (_____), subacute (_____), or “old dog” (_____)

• _____ with _____: brain inflammation ; myelin sheath damage

1. interstitial pneumonia

2. weeks

3. months

4. years

5. encephalitis

6. demyelination

central nervous system signs of canine distemper (CDV)

• _____: involuntary muscle control, twitching

• _____ - chewing gum fits

1. myoclonus

2. seizures

canine distemper (CDV) can cause _____ (hard pad disease) of the nose & footpads - thickening of the skin due to too much keratin

can also attack the _____ cells; in pups, the buds of _____ teeth are still developing & can cause _____ teeth to be stained & have pitted _____ (_____ _____)

1. hyperkeratosis

2. epithelial

3. permanent

4. adult

5. enamel

6. enamel hypoplasia

canine infectious hepatitis (CAV-1): _____ contagious disease (_____) that causes slight fever, _____ _____ membranes to severe _____, _____ (low WBC count), _____ disorders, & _____ (yellowish tint to skin)

1. highly

2. adenovirus

3. congestion mucous

4. depression

5. leukopenia

6. coagulation

7. jaundice

canine hepatitis (CAV-1) is resistant to _____ _____

it survives _____ the host for weeks or months

1. lipid solvents

2. outside

how does canine hepatitis (CAV-1) spread?

1. ingestion of urine (from infected dogs)

2. ingestion of feces (from infected dogs)

3. ingestion of saliva (from infected dogs)

canine hepatitis (CAV-1) is shed through _____ for about >_____ months

1. urine

2. 6

canine hepatitis (CAV-1) target

• initial infection in the _____ _____ & _____ _____ causing _____ (presence of virus in the bloodstream)

• the primary target is the _____ _____ cells; then the _____ & _____ parenchyma, _____, & spleen

• chronic kidney _____

• corneal _____

1. tonsillar crypts

2. peyer patches

3. viremia

4. vascular endothelial

5. renal

6. hepatic

7. lungs

8. lesions

9. clouding

_____ _____ is directly correlated with the severity of canine hepatitis (CAV-1) - result of _____ _____ _____ (widespread clotting in small vessels) & failure of the _____

• _____ (inability to clot - prolonged bleeding)

• _____ (loss of blood from circulatory system)

  • around _____ teeth

1. clotting time

2. disseminated intravascular coagulation

3. liver

4. coagulopathy

5. hemorrhage

6. deciduous

canine hepatitis (CAV-1) & adenovirus-2 (CAV-2) vaccine: a vaccination against _____ _____ viruses; protects against both canine hepatitis & _____ _____ caused by CAV-2

1. closely related

2. respiratory illness

canine adenovirus-2 (CAV-2): one of the leading causes in _____ (inflammation of the trachea & bronchi that connects the _____ to the _____) or “kennel cough”

1. tracheobronchitis

2. lungs

3. trachea

canine hepatitis (CAV-1) vaccines are _____ available in the unitied states anymore due to _____ _____

the canine adenovirus-2 vaccine protects against _____ _____

1. not

2. side effects

3. both adenoviruses