Non fermenter Part 4

Haemophilus spp. are

Small Gram-negative coccobacilli

Haemophilus spp. require

X factor and/or V factor for growth

X factor is

Hemin (iron containing from RBC)

V factor is

Nicotinamide adenine dinucleotide (NAD)

X factor is

Heat stable

V factor is

Heat labile

*a substance is easily changed, damaged, or destroyed by exposure to heat

Best medium for Haemophilus spp.

Chocolate agar

Growth around Staphylococcus aureus on blood agar is called

Satellite phenomenon

Staph helps feed Haemophilus

Haemophilus spp. are what type of breathers

Capnophilic

Natural habitat of Haemophilus spp.

Upper respiratory mucous membranes

Glaesserella parasuis was formerly called

Haemophilus parasuis

Glaesserella parasuis causes

Glässer's disease

Another name for Glässer's disease

Infectious polyserositis syndrome

Primary host of Glaesserella parasuis

Swine

Most susceptible pigs

Young pigs after weaning

Major virulence factors of Glaesserella parasuis

Capsule fimbriae and lipooligosaccharide (LOS)

Function of capsule

Prevents phagocytosis

Function of fimbriae

Attachment to respiratory epithelium

Function of LOS

Causes inflammation and vascular damage

Clinical signs of Glässer's disease

Fever depression anorexia lameness and dyspnea

Neurologic signs of Glässer's disease

Meningitis tremors and convulsions

Joint lesions of Glässer's disease

Polyarthritis

Respiratory lesions of Glässer's disease

Pneumonia

Characteristic lesion of Glässer's disease

Fibrinous polyserositis

Polyserositis includes

Pericarditis pleuritis and peritonitis

Other lesions of Glässer's disease

Meningitis pneumonia and polyarthritis

Control of Glässer's disease

Vaccination and stress reduction

Histophilus somni primarily affects

Cattle

Histophilus somni is normally found in

Upper respiratory and reproductive tract

Disease caused by Histophilus somni

Histophilosis

Predisposing factors for Histophilus somni disease

Stress transportation overcrowding and viral infections

Histophilus somni causes

Thrombotic meningoencephalitis (TME)

Histophilus somni causes

Bronchopneumonia

Histophilus somni causes

Septicemia

Histophilus somni causes

Myocarditis

Histophilus somni causes

Polyarthritis

Histophilus somni causes

Abortion metritis and orchitis

Major pathogenic mechanism of Histophilus somni

Vasculitis with thrombosis

Peracute histophilosis causes

Sudden death

Acute histophilosis causes

Fever dyspnea neurologic signs and pneumonia

Chronic histophilosis causes

Reproductive disease

Characteristic brain lesion of Histophilus somni

Thrombotic meningoencephalitis

Characteristic heart lesion of Histophilus somni

Fibrinosuppurative myocarditis or pericarditis

Characteristic vascular lesion of Histophilus somni

Vasculitis with thrombosis

Characteristic lung lesion of Histophilus somni

Fibrinous bronchopneumonia

Ovine histophilosis commonly affects

Lambs 4-7 months old

Ovine histophilosis causes

Septicemia thrombotic meningoencephalitis pneumonia and polyarthritis

BRDC stands for

Bovine Respiratory Disease Complex

BRDC is caused by

Multiple infectious agents with stress as a major predisposing factor

Major bacterial causes of BRDC

Histophilus somni Mannheimia haemolytica Pasteurella multocida and Mycoplasma bovis

Common stressors predisposing to BRDC

Transportation weaning overcrowding weather changes and commingling

Why is BRDC called a complex?

Disease results from interaction of stress viruses and bacteria

Pseudomonas aeruginosa hallmark clue

Blue-green pigment with fruity grape-like odor

Burkholderia mallei hallmark clue

Glanders diagnosed by the mallein test

Burkholderia pseudomallei hallmark clue

Melioidosis with multiple organ abscesses

Lawsonia intracellularis hallmark clue

Intracellular curved Gram-negative rod causing proliferative enteropathy

Francisella tularensis hallmark clue

Rabbit fever transmitted by ticks and deer flies

Glaesserella parasuis hallmark clue

Young pigs with fibrinous polyserositis

Histophilus somni hallmark clue

Feedlot cattle with thrombotic meningoencephalitis

Which organism produces pyocyanin?

Pseudomonas aeruginosa

Which organism causes glanders?

Burkholderia mallei

Which organism causes melioidosis?

Burkholderia pseudomallei

Which organism causes proliferative enteropathy?

Lawsonia intracellularis

Which organism causes rabbit fever?

Francisella tularensis

Which organism requires X and V factors for growth?

Haemophilus spp.

Which organism causes Glässer's disease?

Glaesserella parasuis

Which organism causes thrombotic meningoencephalitis in cattle?

Histophilus somni

Which disease is characterized by fibrinous polyserositis?

Glässer's disease

Which disease is commonly called shipping fever complex?

Bovine Respiratory Disease Complex (BRDC)

Which organism is WOAH-reportable?

Burkholderia mallei

Which organism is considered a potential bioterrorism agent?

Burkholderia mallei

Which organism commonly spoils refrigerated meat and dairy products?

Pseudomonas aeruginosa

Which non-fermenter is well known for multidrug resistance?

Acinetobacter spp.