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phospholipid
a type of lipid molecule that is the main component of the cell membrane, also acts as a barrier to protect the cell against various environmental insults and more importantly, enables multiple cellular processes to occur in subcellular compartments
amphipathic molecule
chemical compounds containing both polar and nonpolar (apolar) portions in their structure
cholesterol
a structural component of cell membranes and serves as a building block for synthesizing various steroid hormones, vitamin D, and bile acids
polar molecule
a molecule containing an uneven distribution of charge due to the presence of polar covalent bonds; a molecule in which one end of the molecule is slightly positive, while the other end is slightly negative
fluid mosaic model
describes the structure of the cell membrane as a dynamic, flexible structure made up of different components
transmembrane protein
a type of integral membrane protein that spans the entirety of the cell membrane; allows for transport and cell signaling
diffusion
helps in the movement of substances in and out of the cells. The molecules move from a region of higher concentration to a region of lower concentration until the concentration becomes equal throughout
passive transport
the diffusion of a substance across a biological membrane without any input of energy
active transport
a process that involves the movement of molecules from a region of lower concentration to a region of higher concentration against a gradient or an obstacle with the use of external energy
facilitated diffusion
the passive movement of molecules along the concentration gradient aided by specific transport proteins. It is a selective process, i.e., the membrane allows only selective molecules and ions to pass through it
concentration gradient
the difference in concentration of a substance from one point to another; tend to move from areas of high concentration to low concentration
osmosis
the diffusion of water across a selectively permeable membrane
solution
a homogeneous mixture that is made up of a solute dissolved within a solvent
solvent
substance (molecule) with the ability to dissolve other substances (solutes) to form a solution
solute
a substance that can be dissolved into a solution by a solvent
tonicity
the capability of a solution to modify the volume of cells by altering their water content
hypertonic
when the surrounding liquid has a higher concentration of solutes than the intracellular fluid; water flows out of cell
hypotonic
when the surrounding fluid has a lower solute concentration than the intracellular fluid; water flows into the cell
isotonic
any external solution that has the same solute concentration and water concentration as another solution
energy
the capacity to cause change, or to move matter in a direction it would not move if left alone
autotrophs
an organism that can produce its own food using light, water, carbon dioxide, or other chemicals
heterotrophs
an organism that eats other plants or animals for energy and nutrients
aerobic
containing or requiring molecular oxygen
metabolism
the sum of all the chemical reactions in an organisms
ATP
a molecule composed of adenosine and three phosphate groups; the main energy source for cells
calories
the amount of energy that raises the temperature of 1 g of water by 1°C; measure of amount of energy in nutrients
carbohydrates
a biological molecule consisting of a simple sugar (a monosaccharide), two monosaccharides joined into a double sugar (a disaccharide), or a chain of monosaccharides (a polysaccharide); sugars & starches
monosaccharides
the simplest forms of sugar and the most basic units (monomers) from which all carbohydrates are built
disaccharides
a sugar molecule consisting of two monosaccharides (simple sugars) linked by a dehydration reaction
polysaccharides
a carbohydrate polymer consisting of many monosaccharides (simple sugars) linked by covalent bonds
cellulose
a large polysaccharide composed of many glucose monomers linked into cable-like fibrils that provide structural support in plant cell walls; cannot be broken by any enzyme produced by animals
glycogen
the stored form of glucose that's made up of many connected glucose molecules; serves as a temporary energy-storage molecule in liver and muscle cells
starch
a storage polysaccharide found in the roots of plants and certain other cells; a polymer of glucose
herbivore
an organism that mostly feeds on plants or algae
carnivore
an organism that mostly eats meat, or the flesh of animals
omnivore
an organism that eats plants and animals
cellular respiration
Use of oxygen (aerobic) to generate chemical energy (ATP) from organic fuel molecules (sugar); provides the energy cells need to maintain the functions of life; a series of chemical reactions that break down glucose to produce ATP
energy carriers
the source of energy for use and storage at the cellular level (NADH and ATP molecules)
glycolysis
A six-carbon glucose molecule is split in half to form two molecules of pyruvic acid; the energy released from breakdown of glucose is used to produce NADH and ATP molecules
citric acid cycle
the metabolic cycle that is fueled by acetyl CoA formed after glycolysis in cellular respiration; chemical reactions in the cycle complete the metabolic breakdown of glucose molecules to carbon dioxide; the cycle occurs in the matrix of mitochondria and supplies most of the NADH molecules that carry energy to the electron transport chain
electron transport chain
a series of electron carrier molecules that shuttle electrons during a series of chemical reactions; these reactions release energy that is used to make ATP; located in the inner mitochondrial membrane
cristae
a collection of proteins bound to the inner mitochondrial membrane and organic molecules, which electrons pass through in a series of redox reactions, and release energy
matrix
part of the mitochondria where the citric acid cycle takes place
inner and outer mitochondrial membranes
the thin layer that forms the outer boundary of a living cell or of an internal cell compartment
glucose
the main type of sugar in the blood and is the major source of energy for the body's cells
NADH
carries electrons from glucose and other fuel molecules and deposits them at the top of an electron transport chain; generated during glycolysis and the citric acid cycle
fermentation
another anaerobic (non-oxygen-requiring) pathway for breaking down glucose; enable cells to produce ATP
without the use of oxygen
lactic acid
a chemical your body produces when your cells break down carbohydrates for energy
cell division
the reproduction of a cell
mitosis
a process of cell duplication, in which one cell divides into two genetically identical daughter cells
meiosis
in a sexually reproducing organism, the process of cell division that produces haploid gametes from diploid cells within the reproductive organs
asexual reproduction
the creation of genetically identical offspring by a single parent, without the participation of gametes (sperm and egg)
sexual reproduction
the creation of genetically distinct offspring by the fusion of two haploid sex cells (gametes: sperm and egg), forming a diploid zygote
haploid
containing a single set of chromosomes; referring to an n cell
diploid
the presence of two complete sets of chromosomes in an organism's cells, with each parent contributing a chromosome to each pair; referring to a 2n cell
interphase
90% of the cell cycle; ells perform normal functions; cells grow in size (G1/G2 phases) and duplicates its DNA (S phase)
prophase
the first phase of mitosis; Chromosome condensation; breakdown of nuclear envelope; formation of spindle (microtubules) by centrosome
metaphase
Spindle microtubules attach to chromosomes; Chromosomes align in center
anaphase
Spindle pulls apart sister chromatids
telophase
Chromosomes decondense; Spindle apparatus is dismantled; Nuclear envelopes reform around separated chromosomes
cytokinesis
Division of the cytoplasm; Formation of a cleavage furrow, indentation at equator of the cell; Daughter cells pinch off from each other
chromosomes
threadlike structures made of protein and a single molecule of DNA that serve to carry the genomic information from cell to cell
chromatin
chain of nucleosomes (DNA + proteins); condenses into chromosomes during cell division
nucleosomes
a section of DNA that is wrapped around a protein core made up of eight histone molecules
histones
a small protein molecule that provides structural support for a chromosome
sister chromatids
the identical copies (chromatids) formed by the DNA replication of a chromosome; eventually separated during mitosis or meiosis II
cleavage furrow
an indentation that appears in a cell's surface when the cell is preparing to divide
cancer
disease caused when cells divide uncontrollably and spread into surrounding tissues; forms tumors
tumor
an abnormal mass of cells that forms within otherwise normal tissue
spermatogenesis
the formation of sperm cells in the testis
oogenesis
formation of egg cells in the ovaries
gamete
a sex cell; a haploid egg or sperm
genes
A heritable unit of DNA
alleles
Variants/forms of the same gene (blue, green, brown eye color)
karyotype
all the chromosomes in a cell
autosomes
any chromosome other than the sex chromosomes
sex chromosomes
a chromosome that determines whether an individual is male or female
nucleotide
the basic building block of nucleic acids (RNA and DNA)
polynucleotide strand
a polymer made up of many nucleotides covalently bonded together
deoxyribose
a pentose (5-carbon sugar) biological molecule
nucleic acid
consists of many nucleotide monomers; serves as a blueprint for proteins and, through the actions of proteins, for all cellular structures and activities; two types are DNA & RNA
deoxyribo nucleic acid (DNA)
the molecule that carries genetic information for the development and functioning of an organism
nitrogenous base
nitrogenous compounds that form an important part of the nucleotides
adenine
a double-ring nitrogenous base found in DNA and RNA (A pairs with T)
thymine
a single-ring nitrogenous base found in DNA (T pairs with A)
cytosine
a single-ring nitrogenous base found in DNA and RNA (pairs with G)
guanine
a double-ring nitrogenous base found in DNA and RNA (pairs with C)
purine
double carbon rings, include adenine and guanine, which participate in DNA and RNA formation
pyrimidine
single carbon rings, include cytosine and thymine
5’ phosphate group
a phosphorus atom bound to four oxygen atoms
3’ hydroxyl group
the hydrogenated oxygen molecule attached to the 3'; binds to 5’ phosphate group
double helix
the form assumed by DNA in living cells, referring to its two adjacent polynucleotide strands wound into a spiral shape
base pairing
consists of two complementary DNA nucleotide bases that pair together to form a “rung of the DNA ladder.” ([Purines] = [Pyrimidines], [A] = [T] and [G] = [C])
antiparallel
the strands run in opposite directions, parallel to one another
complementary
in a double strand of DNA, adenine will always pair with its complement thymine and cytosine will always pair with its complement guanine
heredity
the transmission of traits/characters from one generation to the next
genetics
the scientific study of heredity—of how certain qualities or traits are passed from parents to offspring as a result of changes in DNA sequence
traits
a variant of a character found within a population, such as purple flowers in pea plants or blue eyes in people
phenotype
physical expression of trait (purple or white flowers)
genotype
genetic (allelic) makeup of individual for specific trait (PP, Pp, pp)