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How is the composition of diaphysis?
mainly compact bone
some trabecular
How is the composition of the metaphysis and epiphysis?
mainly cancellous bone
some cortical bone
How do central canals run?
Haversian canals run straight up and down
Where do blood vessels first associate with in bone?
the periosteum
What's another name for the perforating canal?
volkmann
How many layers does the periosteum have?
2
outer: thick
inner: births osteoblasts
Why is the outer layer of the periosteum so thick?
tendons and ligaments attach to it
What are the 4 kinds of bone cells?
osteoprogenitors
osteoblasts
osteoclasts
osteocytes
What are osteoprogenitors similar to?
cells in the stratum basale: both are mitotically active and have stem cells
When osteoprogenitors divide, what can they become?
osteoblast or chondroblast or another osteoprogenitor
Where can you find osteoprogenitors?
the periosteum and endosteum
What are the osteoblasts doing?
making bone matrix: first organic then inorganic
What is the organic matrix called, and its composition?
osteoid: mainly collagen
After the organic matrix, what do osteoblasts do?
secretes solution that lowers the solubility of calcium and phosphate: makes crystals
What is calcium/phosphate crystal formation an example of?
positive feedback loop
What is the calcium phosphate crystals known as?
the inorganic matrix
When osteoblasts have fufilled their purpose, what happens?
make a bony matrix around itself: now an osteocyte
Where/what are osteocytes?
in lacunae
maintains bone matrix
Where are osteoclasts born from?
hematopoietic tissue
How are osteoclasts made?
from tons of WBCs fusing together