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What primarily makes up intracellular fluid?
potassium and phosphate
What primarily makes up extracellular fluid?
sodium, chloride, bicarb
osmosis
movement of water freely
Filtration
movement of water and solutes
hydrostatic pressure (push)
pressure from fluid pushing against a surface, high to low concentration
What pressures work together to influence the movement of water and solutes?
osmotic and hydrostatic
Osmotic pressure (pull)
pulls fluid from low concentrations of solutes to high concentration of solutes
Thirst mechanism
sensors in interstitial fluid recognize changes in fluid, hypothalamus detects need for more water, thirst sensation increases
What organ excretes/retains sodium and water
kidneys
What hormones are related to fluid and electrolytes?
RAAS, ADH, and ANP
ADH
works to retain water
ANP (atrial natriuretic peptide)
excretes sodium and water (reduces)
When increased fluid is moving through the kidneys
BV increases, hydrostatic pressure increases, fluid moves from capillaries to renal tubules, fluid is excreted as urine
RAAS (renin-angiotensin-aldosterone system)
hormonal pathway to detect decreased BV and bring it back to normal range
What should be considered fluid intake?
water, juice, coffee, tea, milkshakes, smoothies, ice cream, soups,
Sensible losses
visible and measurable fluid losses (urine and feces)
Insensible losses
fluid losses not usually seen or measured (respiration, sweat)
hypovolemia
dehydration, too low BV, insufficient fluid circulating throughout the body
Causes of hypovolemia
vomiting, diarrhea, excessive sweating, poor PO
hypervolemia
too high BV, excessive fluid
Causes of hypervolemia
decreased urinary output or compromised fluid regulation
Signs / symptoms of hypervolemia
weight gain, edema, ascites, elevated BP
signs / symptoms of hypovolemia
dry mouth, poor skin turgor, elevated BUN/Cr, decreased moisture in oral cavity
What specific chronic diseases relate to fluid and electrolyte balance?
CKD, heart failure, and liver cirrhosis
chronic kidney disease (CKD)
insufficient renal function; Na and water are retained because kidneys can’t filter
heart failure
insufficient blood flow due to reduced cardiac output; body perceives low BV and increases fluid retention
liver cirrhosis
failed fluid circulation, fluid moves into third spaces
1 liter of fluid loss equals
2 lbs
mild fluid volume deficit or excess
2% loss/gain
moderate fluid volume deficit or excess
5% loss/gain
severe fluid volume deficit or excess
8% loss/gain
hyponatremia
too low sodium
hypernatremia
excessive sodium
hypokalemia
too low potassium
hyperkalemia
excessive potassium
Electrolyte labs include
Na, K+, Cl, Ca, phos, Mg
Third spaces/spacing
fluid accumulation in spaces between organs, caused by illness or injury
What spaces don’t contribute to typical circulation of fluids?
peritoneal, pericardial, thoracic
Patients with dehydration and severe electrolyte abnormalities may experience
confusion, fatigue, dry mouth, dizziness/nausea
When is fluid restriction indicated?
individualized care is recommended, severe heart failure with hyponatremia or congestion, or if sodium restriction + diuretic use isn’t helping with fluid retention
Typical fluid restriction amount
1.5-2 L fluid
When should restrictive diets be avoided?
if poor appetite or inadequate oral intake are present
Once PO intake is improved and meeting __ % of needs, then consider diet restriction if indicated
75
fluid & electrolyte assessment
medications, labs, weight, NFPE, nutrition information
What medications should you assess for?
ACE inhibitors and diuretics
What labs should you assess for?
albumin, BUN, sodium (ABS), electrolytes, Cr, GFR
What should you assess in the NFPE?
edema
What should you assess in diet / nutrition information?
fluid intake and sources of electrolytes
common diagnoses for fluid & electrolyte imbalances
altered nutrient related labs, food & nutrition knowledge deficit, unintentional weight gain, inadequate or excessive fluid intake
common interventions for fluid & electrolyte imbalances
nutrition education, adjusting free water flushes or EN formula, IVF changes, daily weigh ins
monitoring / evaluation for fluid & electrolyte imbalances
stable dry weight, fluid-related labs, electrolyte levels, compliance with fluid restricted diet if indicated