4.2.2.4 Coronary heart disease: a non-communicable disease

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Biology

9th

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What are cardiovascular diseases
Diseases of the heart and blood vessels

Non-communicable
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Coronary heart disease
Coronary arteries provide oxygen to the muscle cells of the heart

In coronary heart disease layers of fatty material build up inside the coronary arteries

Causes coronary arteries to narrow

Effect of this is to reduce the flow of blood through coronary arteries

Results in a lack of oxygen for the heart muscle

Result in heart attack- where heart is starved of oxygen
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Treatments for coronary heart disease
Statins
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Statins
Drugs which reduce the level of cholesterol in the blood

Slows down the rate that fatty materials build up in the arteries
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Advantages of statins
Proves to reduce coronary heart disease

Reduces the amount of bad cholesterol present in bloodstream - reduce the risk of strokes, coronary heart disease and heart attacks

Increase the amount of beneficial cholesterol in bloodstream

Prevent other diseases forming

Slows down the rate of fatty deposits forming
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Disadvantages of statins
Long term drug that must be taken regularly (risk someone could forget )

Unwanted side- effects Eg liver problems

Effect isn’t instant
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Stent
In people where there is a total blockage of coronary artery

A stent is a tube which can be inserted into the coronary artery to keep it open
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Advantages of stents
Blood can flow normally through artery

Effective for a long time and fairly quick surgery recovery time
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Disadvantages of stent
Will not prevent other regions of the coronary arteries from narrowing

Does not treat underlying causes of the disease

Risk of complications during surgery(heart attack)

Risk of infection

Risk of developing bloodclot near stent
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Problems with valves
Can be damages or weakened by heart attacks, infection or old age

Sometimes valves do not fully open as the valve tissues stiffen so heart has to pump extra hard

Causes heart to enlarge

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Valves are leaky which can cause the patient to feel weak and tired

Blood does not circulate as effectively as normal
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mechanical valve
Can last a lifetime

They increase the risk of blood clots- patients have to take anti-clotting drugs

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Constant medication needed to stop blood clotting
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Valve from animal
Don’t last as long, may need to be replaced

Don not need to take drugs

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Only last 12-15 years
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Heart failure
Heart cannot pump enough blood around the body
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Lung and heart donation
Disadvantages:

Not enough donated heart’s available to treat every patient

Must take drugs to stop donated heart to be rejected by immune system
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Artificial heart
Mechanical devices that pump blood for a person

Temporary solution while waiting for heart transplant or allow damaged heart to

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Advantages of artificial hearts
Less likely to be rejected by the body’s immune system than a donation heart
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Disadvantages of artificial hearts
Increase risk of blood clotting- only used for a relatively short amount of time

Surgery to fit artificial heart can lead to bleeding and infection

Don’t work as well as natural ones

Electrical monitors can fail

Blood Disney flow through artificial hearts as smoothly- can lead to blood clots and strokes

Has to take drugs to thin blood
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Artificial blood
Extreme blood loss- can be solved by giving artificial blood

It is a salt solution that can keep people alive, even if they lose 2/3 of the red blood cells

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This means that patients have more time to produce new blood cells

But it can only be used for short periods of time, then a blood transfusion has to take place