Lysosomal / Lipid Storage Disorders (LSD)

A set of vocabulary flashcards covering the specific enzyme defects associated with the eight primary types of Lysosomal Storage Disorders discussed in the lecture.

Gaucher's disease

The most common ($MC$) type of lysosomal storage disorder ($LSD$), caused by a defect in Beta glucosidase / Glucocerebrosidase.

Niemann-Pick Disease (A+B)

A lysosomal storage disorder caused by a defect in the enzyme Sphingomyelinase.

Krabbe's disease

A lysosomal storage disorder caused by a defect in the enzyme Beta galactosidase.

Metachromatic leukodystrophy

A lysosomal storage disorder caused by a defect in the enzyme Arylsulfatase $A$.

Farber disease

A lysosomal storage disorder caused by a defect in the enzyme Ceramidase.

Tay Sach's disease

A lysosomal storage disorder caused by a defect in the enzyme Hexosaminidase $A$.

Sandhoff's disease

A lysosomal storage disorder caused by a defect in the enzyme Hexosaminidase $A+B$.

Fabry's disease

A lysosomal storage disorder caused by a defect in the enzyme Alpha galactosidase $A$; it is unique among the group for being inherited as an $X$-linked recessive ($X-L-R$) trait.

Gm1 Gangliosidosis

A specific type of gangliosidosis identified within the lysosomal storage disorders.