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Genotype
an organisms genetic makeup including specific alleles it carries for a given trait
Phenotype
in organisms observable traits: appearance, behavior, physiology from reacting with environment
Genome
complete set of genetic material in an organism, including genes and non-coding sequences
Transcriptome
complete set of RNA molecules transcribed from the genome in a cell or organism at a given time
Proteome
entire set of proteins produced by a cell, tissue, or organism at a given time. It varies based on genes, environment, and cellular conditions
performance structural, enzymatic, and regulatory functions, hormone, transport, immunity, movement
What are the functions of proteins?
Store and transmit genetic info
What are the functions of nucleic acids?
transcription and translation
How do you make proteins?
Transcription
DNA is copied into messenger RNA in the nucleus
Translation
ribosomes read the mRNA and assembled amino acids into a protein using transfer RNA
mRNA: Messenger RNA
Carries genetic instructions from DNA to ribosomes for protein synthesis
rRNA: ribosomal RNA
Forms part of ribosomes and helps assemble proteins
tRNA: transfer RNA
brings amino acid to ribosomes during translation, helps translate genetic information into proteins
siRNA
immune function, recently discovered
RNA world hypothesis
early life relied on RNA as both genetic material and a catalyst before DNA and proteins evolved
Central dogma
transcription converts genetic instructions into mRNA, and translation uses that mRNA to build proteins carrying out the cellular functions
Autosome
non-sex chromosomes that contain genes for general traits. Humans have 22 pairs
Sex chromosomes
determine in organisms biological sex, one pair XX or XY
Karyotype
organize display of an organisms chromosomes, used to examine their number, size, and structure
Diploid
a cell with two sets of chromosomes, one from each parent, 46 chromosomes 2N
Haploid
a cell with one set of chromosomes, sperm and egg, 23 chromosomes
Homologous chromosomes
pairs of chromosomes, one from each parent, with the same gene but possibly different alleles
Sister chromatids
identical copies of a chromosome, joined at the centromere formed during DNA replication