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is the study of diseases that can cause abnormalities in the structure or function of various organ systems
Pathology
Any abnormal disturbance of the function or structure of the human body as a result of some type of injury
Disease
Refers to the patient’s perception of the disease.
Symptoms
A patient showing no evidence of diseases is considered
Asymptomatic
are adverse responses to medical treatment itself
Iatrogenic
A term to a disease if there is no causative factor can be identified
Idiopathic
Diseases that have a quick onset and last for a short period
Acute
Diseases may manifest more slowly and last for a very long time.
Chronic
Describes the expected patient outcome
Prognosis
Incidences of the development of infections at the acute care facility
Nosocomial
Infections that develop outside the healthcare facility
Community acquired
is the investigation of disease in large group
Epidemiology
refers to the number of cases found in a given population
Prevalence
refers to the number of new cases found in a given period.
Incidence
is a generalized decrease in cell size.
Atrophy
is a generalized increase in cell size
Hypertrophy
is an increase in the number of cells in a tissue as a result of excessive proliferation.
Hyperplasia
a is the conversion of one cell type into another cell type that is not normal for that tissue
Metaplasia
refers to abnormal changes of mature cells.
Dysplasia
is the initial response of body tissues to local injury.
Acute Inflammation
The earliest bodily response to local injury is?
Dilation of arerioules, capillaries and venules
produces the heat and redness associated with inflammation.
hyperemia
results in the swelling associated with inflammation, which produces pressure on sensitive nerve endings and causes pain.
Exudate
a low-protein fluid such as that seen in the pulmonary edema that develops in congestive heart failure.
transudate
These white blood cells cross the capillary walls into the injured tissues, where they engulf and enzymatically digest infecting organisms and cellular debris, a process called
phagocytosis.
tissue refers to a combination of young developing capillaries and actively proliferating fibroblasts, which produce connective tissue fibers (collagen) that replace the dead tissue.
Granulation
The five clinical signs of acute inflammation are
Rubor(redness) , Calor(hear), Tumor(swelling), Dolor(pain), Loss of function
is the accumulation of abnormal amounts of fluid in the intercellular tissue spaces or body cavities
Edema
in filariasis, a parasitic worm causes lymphatic obstruction, and the resulting localized edema is termed
elephantiasis
results from an inflammatory reaction.
Localized Edema
occurs with pronounced swelling of subcutaneous tissues throughout the body (anasarca).
Generalized Edema
Occurs most frequently in patients with congestive heart failure, cirrhosis of the liver, and certain forms of renal disease.
Generalized Edema
refers to an interference with the blood supply to an organ or part of an organ
Ischemia
is a localized area of ischemic necrosis within a tissue or organ produced by occlusion of either its arterial supply or its venous drainage
Infarct
The two most common clinical forms of infarction are
Myocardial and pulmonary
In cases in which ischemia continues to progress, resulting in an infarction, necrosis may occur as a result of lack of blood flow. This progressive situation can lead to a condition called
Gangrene
implies rupture of a blood vessel.
Hemorrhage
Hemorrhage may be external, or the blood may be trapped within body tissues, resulting in an accumulation termed a
Hematoma
Minimal hemorrhages into the skin, mucous membranes, or serosal surface
Petechiae
Slightly larger hemorrhages
Purpura
A large (>1 to 2 cm) subcutaneous hematoma, or bruise.
Ecchymosis
from the Latin word for “new growth,” refers to an abnormal proliferation of cells that are no longer controlled by the factors that govern the growth of normal cells
Neoplasia