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state the 4 types of circulatory systems?
single
double
open
closed
how does blood pass within a single circulatory system?
blood only passes through the heart once for each complete circuit of the body
how does blood pass within a double circulatory system?
blood passes through the heart twice for each complete circuit of the body
how does the heart pump blood in fish?
the heart pumps blood to the gills to pick up oxygen then to the rest of the body to deliver oxygen in a single circuit
how does the heart pump blood in mammals?
the right side of the heart pumps blood to the lungs to pick up oxygen
it then travels to the left side of the heart which pumps to the rest of the body
when blood returns to the heart it enters the right side again
state an advantage of the mammalian double circulatory system?
blood travels more faster so oxygen is delivered to the tissues more quickly at a higher pressure
what circulatory system do vertebrates have?
a closed circulatory system
define the closed circulatory system?
the blood is enclosed within blood vessels
the heart pumps blood into arteries
these branch out into millions of capillaries
substances like oxygen and glucose diffuse from the blood in the capillaries in the body cells
veins take the blood back to the heart
what type of circulatory system do invertebrates have?
an open circulatory system- blood isnt enclosed in blood vessels all the time therefore flows freely through the body cavity
how does blood flow in an open circulatory system?
the blood flows freely from the heart into the body cavity and comes into direct contact with the cells
exchange of substances takes place before returning to the heart through open ended vessels
what is the function of arteries?
carry blood away from the heart to the rest of the body
what is the structure of arteries?
thick muscular elastic walls which stretch and recoil as the heart beats to help maintain high pressure
which arteries do not carry oxygenated blood?
pulmonary arteries
what structures do arteries branch into?
arterioles
state the function of arterioles?
smooth blood vessels which distribute blood from an artery to a capillary
structure of arterioles?
walls containing rings of smooth muscle allowing them to expand or contract controlling blood flowing into tissues
what structures do arterioles branch into?
capillaries
which is the smallest blood vessel?
capillaries
state how capillaries are adapted for efficient diffusion?
their walls are one cell thick
what structures do capillaries branch into?
venules
what do venules join together to form?
veins
function of veins?
carry blood towards the heart at low pressure
have valves to prevent backflow
do veins carry oxygenated or deoxygenated blood?
deoxygenated blood as the oxygen has been used up by body cells
which vein carries oxygenated blood?
pulmonary vein
which blood vessel has the largest lumen?
the veins
which blood vessel has the most muscular walls?
arteries
define tissue fluid?
the fluid that surrounds cells in tissues
what is tissue fluid made from?
substances which leave the blood plasma
why dont tissue fluids contain red blood cells or big proteins?
because they are too large to be pushed through capillary walls
define capillary bed?
the network of capillaries in an area of tissue
define hydrostatic pressure?
the pressure created by a fluid pushing against the container that its within
define oncotic pressure?
the pressure created by osmotic effects of the solutes in a solution
define lymphatic system?
drains surplus tissue fluid away from the cells
how is tissue fluid formed?
high blood pressure causes hydrostatic pressure forces fluid out filtered by holes in the capillary
large proteins remain in the capillary generate opposing force- oncotic pressure
how does tissue fluid return?
low water potential in capillary due to plasma proteins
water enters capillary by osmosis due to oncotic pressure
lymphatic system drains surplus fluid
what is tissue fluid formed from?
blood
what is lymph formed from?
tissue fluid
where does the right side of the heart pump blood to, oxygenated or deoxygenated?
pumps deoxygenated blood to the lungs
where does the left side of the heart pump blood to, oxygenated or deoxygenated?
pumps oxygenated blood to the rest of the body
what do the atrovetricula valves link together?
link the atria to the ventricles
what do the semi lunar valves link together?
link the ventricles to the pulmonary artery and aorta
what do ventricles prevent?
the backflow of blood
define systole?
contracting
define diastole?
relaxing
define myogenic?
can contract and relax without receiving signals from nerves
define the SAN?
sino atrial node
where is the sino atrial node located?
in the wall of the right atrium
state the function of the SAN?
it sets the rhythm of the heart beat by sending out regular waves of electrical activity to the atrial walls
how does the SAN affect the right and left atrium after sending waves?
causes the right and left atria to contract at the same time
what does a band of non conducting collagen prevent?
the waves of electrical activity from being passed from the atria to the ventricles
where are the electrical waves of activity transferred instead?
transferred from the SAN to the AVN
what is the AVN responsible for?
for passing the waves of electrical activity on to the bundle of His
define the bundle of His?
a group of muscle fibres responsible for conducting the waves of electrical activity to the finer muscle fibres in the right and left ventricle walls called purkyne tissue
what does the purkyne tissue carry?
carries the waves of electrical activity into the muscular walls of the right and left ventricles causing them to contract causing them to simultaneously contract from the bottom to the top
what does the term ECG stand for?
electrocardiograph
what is the name of the trace produced by an electrocardiogtraph?
an electrocardiogram
what does the P wave represent?
contraction/ depolarization of the atria
what is the main peak of the heartbeat called?
the QRS
what does the QRS represent?
ventricular contraction/ depolarisation
what does the T wave represent?
ventricular relaxation/ repolarisation
what does the height of the wave indicate?
how much electrical charge is passing through the heart
define tachycardia?
fast heartbeat, 120bpm
define bradycardia?
slow heartbeat <60 bpm
when can an ectopic heartbeat occur?
when the atria or ventricle has had an extra contraction
define ventricular fibrillation?
a really irregular heartbeat
what do red blood cells contain?
haemoglobin
define haemoglobin?
a large protein with a quaternary structure
what element gives haemoglobin its red colour?
iron
define affinity for oxygen?
the tendency to combine with oxygen
does haemoglobin have a high or low oxygen affinity?
high oxygen affinity
how many oxygen molecules can each haemoglobin molecule carry?
4 oxygen molecules
in the lungs, what is formed when oxygen joins the iron in haemoglobin?
oxyhaemoglobin
what is the unit of partial pressure?
pO2
what is partial pressure a measure of?
oxygen concentration
what does the greater the concentration of dissolved oxygen in cells result in?
a higher partial pressure
what is the unit for partial pressure of carbon dioxide?
pCO2
what is the partial pressure of carbon dioxide a measure of?
the concentration of carbon dioxide in a cell
what does haemoglobin’s affinity for oxygen vary depending on?
depending on the partial pressure of oxygen
what happens at high pO2 ?
oxygen loads onto haemoglobin to form oxyhaemoglobin
what happens at low pO2?
oxyhaemoglobin unloads its oxygen
do the alveoli have high or low pO2?
high pO2
when cells respire does this increase or decrease pO2?
decreases pO2
where do red blood cells deliver oxyhaemoglobin?
to respiring tissues where it unloads its oxygen, the haemoglobin then returns to the lungs to pick up more oxygen
what does an oxygen dissociation curve show?
how saturated the haemoglobin is with oxygen at any given partial pressure
what happens where pO2 is high?
haemoglobin has a high affinity for oxygen so has a high saturation of oxygen
what happens where pO2 is low?
haemoglobin has low affinity for oxygen
releases oxygen rather than combining with it
has low oxygen saturation
what does 100% saturation mean?
every haemoglobin molecule is carrying the maximum of 4 molecules of oxygen
what does 0% saturation mean?
none of the haemoglobin molecules are carrying any oxygen
how do adult and fetal haemoglobin differ?
fetal haemoglobin has a higher affinity for oxygen
why does the fetus have higher oxygen affinity in its haemoglobin?
in order to survive
what would happen if the fetal haemoglobin had the same oxygen affinity as adult haemoglobin?
its blood wouldnt be saturated enough
what does CO2 react with water to form?
carbonic acid
which enzyme is carbonic acid catalysed by?
carbonic anhydrase
what does carbonic anhydrase dissociate to form?
H+ ions and HCO3- ions
what does an increase in H+ ions cause, forming what acid?
causes oxyhaemoglobin to unload its oxygen so that haemoglobin can take up the H+ ions forming haemoglobinic acid
what do the HCO3- ions diffuse out of and where are they transported?
diffuse out of red blood cells and are transported in the blood plasma
which ions diffuse into the red blood cells to compensate for HCO30 loss?
Cl- ions
what does the chloride shift maintain?
the balance of charge between the red blood cell and the plasma
when blood reaches the lungs and there is low pCO2, which ions recombine into CO2?
HCO3- and H+ ions
where does CO2 then diffuse to be breathed out?
diffuses into tthe alveoli