Bio Chap 13 & 14 - DNA structure and protein synthesis

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What did Frederick Griffith do?

He wanted to determine how bacteria were able to cause pneumonia. He set up two bacterial strains, one disease-causing and one harmless.

He then injected heat-killed versions of the disease-causing bacteria into the mice. Many mice survived. But after injecting them with a mixture of heat-killed dangerous bacteria and healthy harmless bacteria, many mice died.

The disease-causing bacteria had passed their deadly ability to the harmless strain.

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What did Oswald Avery do after that?

He repeated Griffith’s work. He had a strain of heat-killed dangerous bacteria, and after treating it with enzymes that destroyed proteins, lipids, carbohydrates, and RNA found that it could still pass on its disease-causing ability. But this ability was lost the moment he treated it with enzymes that destroyed DNA.

He was the first scientist to show that DNA was the genetic factor.

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What is a bacteriophage?

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