Quiz 8 - Antiseizures, Thyroid, Insomnia, & ADHD

What is the brand name of Gabapentin?

Neurontin

What is the medication class of Gabapentin?

Anticonvulsant

What is the therapeutic category of Gabapentin?

Anticonvulsant

What is the basic mechanism of Gabapentin?

Modulates the activity of voltage-gated calcium channels in the CNS by binding to the alpha-2-delta subunit and indirectly influences GABAergic activity

What is the brand name of Levetiracetam?

Keppra

What is the medication class of Levetiracetam?

Anticonvulsant

What is the therapeutic category of Levetiracetam?

Anticonvulsant

What is the basic mechanism of Levetiracetam?

Inhibits voltage-dependent N-type calcium channels, facilitates GABA-ergic inhibition, and binds to synaptic proteins to modulate neurotransmitter release

What is the brand name of Lamotrigine?

Lamictal

What is the medical class of Lamotrigine?

Anticonvulsant

What is the medical category of Lamotrigine?

Anticonvulsant

What is the basic mechanism of Lamotrigine?

Inhibits voltage-sensitive sodium channels, stabilizing neuronal membranes and reducing the release of excitatory neurotransmitters

What are the brand names of Topiramate?

Topamax, Trokendi XR

What is the medical class of Topiramate?

Anticonvulsant

What is the medical category of Topiramate?

Anticonvulsant

What is the basic mechanism of Topiramate?

Blocks neuronal voltage-dependent sodium channels, enhances GAB(A) activity, antagonizes AMPA/kainate glutamate receptors, and weakly inhibits carbonic anhydrase

What is the brand name of Phenytoin?

Dilantin

What is the medical class of Phenytoin?

Hydantoin

What is the medical category of Phenytoin?

Anticonvulsant

What is the basic mechanism of Phenytoin?

Stabilizes neuronal membranes and decreases seizure activity by increasing efflux or decreasing influx of sodium ions across cell membranes in the motor cortex during generation of nerve impulses

What is the brand name of Levothyroxine?

Synthroid

What is the medical class of Levothyroxine?

Thyroid hormone

What is the medical category of Levothyroxine?

Hyperthyroidism agent

What is the basic mechanism of Levothyroxine?

Synthetic form of thyroxine that is converted to active metabolite T3 which binds to thyroid receptor to increase its effects

What is the brand name of Zolpidem?

Ambien

What is the medical class of Zolpidem?

Hypnotic

What is the medical category of Zolpidem?

Hypnotic

What is the basic mechanism of Zolpidem?

Enhances the activity of GABA by binding to the benzodiazepine receptor subtype BZ1, which increases GABA’s inhibitory effects

What is the brand name of Eszopiclone?

Lunesta

What is the medical class of Eszopiclone?

Hypnotic

What is the medical category of Eszopiclone?

Hypnotic

What is the basic mechanism of Eszopiclone?

May interact with GABA-receptor complexes at binding domains located close to or allosterically coupled to benzodiazepine receptors

What is the brand name of Lisdexamfetamine?

Vyvanse

What is the medical class of Lisdexamfetamine?

Central Nervous System Stimulant

What is the medical category of Lisdexamfetamine?

Stimulant (ADHD)

What is the basic mechanism of Lisdexamfetamine?

Prodrug of dextroamphetamine; increases the release of norepinephrine and dopamine in the brain

What is the brand name of Dextroamphetamine/Amphetamine?

Adderall

What is the medical class of Dextroamphetamine/Amphetamine?

Central Nervous System Stimulant

What is the medical category of Dextroamphetamine/Amphetamine?

Stimulant (ADHD)

What is the basic mechanism of Dextroamphetamine/Amphetamine?

Promotes the release of dopamine and norepinephrine from their storage sites in presynaptic nerve terminals in the brain