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T/F: Gradual chronic changes are more dangerous than sudden, acute changes in blood pH, and and tend to be associated with more serious clinical manifestations
False (acute)
T/F: An ABG only gives you snapshot of what is happening at that exact moment in time
True
What system do you get an ABG from (arterial or venous)
Arterial ONLY
1 multiple choice option
What patients often benefit from the use of supplemental oxygen, especially during exertion
Patients with low oxygen saturations
What is the most accurate method of assessing a patient's oxygenation, and acid–base status?
Arterial Blood Draw
T/F: Current technology allows for continuous monitoring of a patient's status
False (does not)
Normal value & range: pH (2)
- 7.4
- 7.35-7.45
Normal value & range: PCO2 (2)
- 40
- 35-45
Normal value & range: PO2 (2)
- 97
- >80
Normal value & range: HCO3 (2)
- 24
-22-28
Normal range: PaCO2
35-45
PaO2: normal
80-100
PaO2: mild hypoxemia
70-80
PaO2: moderate hypoxemia
60-69
PaO2: severe hypoxemia
<60
What is the primary pH buffer system in the human body?
HCO3/CO2 chemical equilibrium system
What common household item does Nan think bicarbonate is like?
baking soda, it is a basic substance that will raise the pH of a solution
What drink does Nan think of when she thinks of CO2 (something acidic)
Soda
If you are increasing HCO3, it will raise the pH of the blood and make it more ___ , whereas if you decrease bicarbonate the blood will become more ___ (decreasing pH)
alkalotic, acidic
1 multiple choice option
HCO3 functions as an ___ substance
alkalotic
1 multiple choice option
Increases in HCO3 will make blood more...
alkalotic
1 multiple choice option
decreases in HCO3 will make blood more...
acidic
1 multiple choice option
CO2 functions as an ___ substance
acidic
1 multiple choice option
Increases in CO2 will make blood more...
acidic
1 multiple choice option
decreases in CO2 will make blood more...
alkalotic
1 multiple choice option
ACIDOSIS: pH less than what?
7.35
ACIDOSIS: Metabolic cause
decreased HCO3 in the blood
Decreased HCO3 in the blood can be d/t (3)
- Severe diarrhea
- Severe dehydration
- Prolonged lack of O2 from HF
ACIDOSIS: Respiratory cause
Buildup of CO2 in the blood
What can cause a buildup of CO2 in the blood
Hypoventilation
1 multiple choice option
What population/diseased population is prone to ↑ of CO2 in blood
COPD (obstructive lung disease)
ALKALOSIS: Metabolic cause
Increased HCO3 in the blood
What can cause an increased HCO3 in the blood (3)
- Prolonged vomiting
- Severe hypokalemia/low potassium
- Excessive use of diuretics
ALKALOSIS: Respiratory cause
Decreased CO2 in the blood
What can cause a decreased CO2 in the blood
- Hyperventilation
1 multiple choice option
When the respiratory system causes abnormal blood pH, the ___ system can attempt to regulate that pH.
Renal
1 multiple choice option
Renal compensation: In acidosis, the kidneys generate ___ and clear acid (to clear CO2)
Bicarbonate
1 multiple choice option
Renal compensation: In alkalosis, ___ HCO3 is reabsorbed by the kidneys, thus lowering the pH
Less
1 multiple choice option
When metabolic systems cause abnormal blood pH, the ___ system can attempt to regulate that pH by varying the respiratory rate
Respiratory
1 multiple choice option
Respiratory compensation: In acidosis, chemoreceptors sense the decreased pH, ___ rate and depth of breathing
Increase
1 multiple choice option
Respiratory compensation: In alkalosis, the breathing rate is ___
Decreased
1 multiple choice option
What causes what?: Step 1... what do you do
Check pH level
What causes what?: Step 2... what do you do
Check paCO2 and HCO3 levels
What causes what?: Step 3... what do you do
Determine if acid/base is respiratory or metabolic
How do determine if acid/base is respiratory or metabolic
The value trending in the same direction as the pH is the cause of the imbalance
Value trending in the same direction as the pH: paCO2
Respiratory
1 multiple choice option
Value trending in the same direction as the pH: HCO3
Metabolic
1 multiple choice option
What causes what?: Step 4... what do you do
Determine if compensations are present
Determine if compensations are present: if pH is normal
Fully compensated
Determine if compensations are present: partially compensated
If CO2 & HCO3 are trending in opposite directions, but pH is not normal, the body is attempting to compensate
What is happening??
pH= 7.48
PaCO2= 28
HCO3= 24
PaO2= 54
Non compensated respiratory alkalosis
What is happening??
pH: 7.84
CO2: 45
HCO3: 36
Metabolic alkalosis
What is happening??
pH: 7.1
CO2: 20
HCO3: 13
Partially compensated metabolic acidosis
Interpretation/what is happening?
FiO2 = .80 (w/ O2)
PaO2 = 79
PaCO2 = 40
pH = 7.33
HCO3 = 21
Metabolic acidosis, not compensated
FiO2: What is it and what is normal (2)
- Fraction of inspired oxygen
- Normal: 21%
Interpretation/what is happening?
FiO2 = .21 (w/ out O2)
PaO2 = 79
PaCO2 = 30
pH = 7.33
HCO3 = 20
Metabolic acidosis, partially compensated
Interpretation/what is happening?
FiO2 = 0.21 (w/ out O2)
PaO2 = 55
PaCO2 = 60
pH= 7.40
HCO3 = 31
Respiratory acidosis, fully compensated
Interpretation/what is happening?
pH=7.22
pCO2=57
HCO3=26
Respiratory acidosis, not compensated
Interpretation/what is happening?
pH=7.23
pCO2=54
HCO3=30
Respiratory acidosis, partially compensated
Interpretation/what is happening?
pH=7.58
pCO2=45
HCO3=35
Metabolic alkalosis, not compensated
Interpretation/what is happening?
pH=7.54
pCO2=23
HCO3=25
Respiratory alkalosis, not compensated
Interpretation/what is happening?
pH=7.29
pCO2=35
HCO3=16
Metabolic acidosis, not compensated
Interpretation/what is happening?
PH=7.6
pCO2=42
HCO3=35
Metabolic alkalosis, not compensated