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Acute pain: <__ month
1
Subacute pain: __-___ months
1-3
Chronic pain: >__ months
3
The guidelines exclude:
1. ___ cell disease
2. ___-related pain treatment
3. palliative care
4. end of __ care
sickle, cancer, life
Patient "Rights"
-right ___
-right __
-right ___
-right ___
drug, dose, ROA, time
4 decisions when prescribing opioids
1. whether or not to __ opioids
initiate
4 decisions when prescribing opioids
2. ___ opioids and determining ___
selecting, doses
4 decisions when prescribing opioids
3. deciding __ of opioid prescription
duration
4 decisions when prescribing opioids
4. assessing __ and addressing potential __ of opioid use
risk, harms
Recommendation 1
-clinicians should maximize use of __ and __ pharmacologic therapies as appropriate for the specific condition
nonpharmacologic, nonopiod
Recommendation 1
-exception to starting with nonpharm/nonopioid =
-acute pain that may require opioids like severe traumatic ___ (car crash/burns) or invasive ___
injury, surgeries
Recommendation 2
-Before starting opioid therapy for subacute or chronic pain, clinicians should discuss with patients the realistic ___ and known ___ of opioid therapy, should work with patients to establish treatment goals for pain and function, and should consider how opioid therapy will be ___ if benefits do not outweigh risks.
benefits, risks, discontinued
Recommendation 2
-To guide patient-specific selection of therapy, clinicians should
evaluate patients and establish or confirm the diagnosis. ___ of pain is important: biomechanical, mechanical, neurological, psychological, non-mechanical !!
Etiology
Etiology of Pain
____: poor posture/movement,
patterned movements
biomechanical
Etiology of Pain
____: sprains, fractures, structural problem
Mechanical
Etiology of Pain
___: shingles, diabetes, tumors, medications
Neurological
Etiology of Pain
____: anxiety, depression,stress
Psychological
Etiology of Pain
__-___: infections, neoplasms,
atherosclerosis
Non-mechanical
Recommendation 3
When starting opioid therapy for acute, subacute, or chronic pain, clinicians should prescribe ___-release opioids instead of extended-release and long-acting (ER/LA) opioids.
immediate
ER/LA formulations ARE NOT for:
-___ pain
-___ use
-___ for subacute or chronic pain.
acute, prn, initiation
ER/LA formulations ARE for:
-subacute or chronic pain (but only after IR has been tried)
-continuous ___ pain (including malignant pain).
severe
Recommendation 4
-When opioids are initiated for opioid-naïve patients with acute, subacute, or chronic pain, clinicians should prescribe the ___ effective dosage
lowest
The ___ starting dose for opioid-naïve patients is often equivalent to a single dose of approximately 5-10 MME or a daily dosage of 20-30 MME/day
lowest
Recommendation 5
-If benefits outweigh risks of continued opioid therapy, clinicians should work closely with patients to ___ nonopioid therapies while continuing opioid therapy.
optimize
Recommendation 5
-If benefits do not outweigh risks of continued opioid therapy, clinicians should optimize other therapies and work closely with patients to gradually taper to ____ dosages or, if warranted based on the individual circumstances of the patient, appropriately taper and discontinue opioids.
lower
In situations where benefits and risks of continuing opioids are considered to be close or unclear, ___ decision-making with patients is particularly important.
shared
Patient ___ and interest in tapering is likely to be a key component of successful tapers!
agreement
Recommendation 6
When opioids are needed for acute pain, clinicians should prescribe no greater quantity than ____ for the expected duration of pain severe enough to require opioids.
needed
Patients should be evaluated at least every ___ weeks if they continue
to receive opioids for acute pain
2
Recommendation 7
-Clinicians should evaluate benefits and risks with patients within ___-__ weeks of starting opioid therapy for subacute or chronic pain or of dosage escalation
1-4
When initiating extended-release/long-acting (ER/LA) opioids or when total daily opioid dosage is >50 MME/day, clinicians should follow up on ___ end of 1-4 week range, because increased risk of overdose!
lower
Additionally, follow-up intervals (every 2-3 days for the first week) should be strongly considered when starting or increasing the dosage of ___
methadone
Recommendation 8
-Before starting and periodically during continuation of opioid therapy, clinicians should ____ risk for opioid-related harms and discuss risk with patients.
evaluate
Clinicians should ask patients about their ___ and ___ use
drug, alcohol
When considering initiating long-term opioid therapy, clinicians should ensure that treatment for depression and other ___ health conditions is optimized
mental
Special Populations to consider in terms of RISK:
-Patients with ___ apnea
-Patients that are ___ or postpartum
sleep, pregnant
Special Populations to consider in terms of RISK:
-Patients with hepatic/renal insufficiency
-Patients ≥___yo
65
Special Populations to consider in terms of RISK:
-Patients with safety critical ___
-Patients with ___ health conditions
jobs, mental
Special Populations to consider in terms of RISK:
-Patients with ___ use disorder
-Patients with previous ___ history
substance, overdose
Recommendation 9
-Review prescription drug monitoring data (____) before initiating opioids and periodically during chronic therapy to identify high-risk dosages or combinations that increase overdose risk.
PDMP
PDMP data should be reviewed ___ every opioid prescription for acute, subacute, or chronic pain and then every __ months or more frequently.
before, 3
Recommendation 10
-When prescribing opioids for subacute or chronic pain, clinicians should consider the benefits and risks of ___ testing to assess for prescribed medications as well as other prescribed and nonprescribed controlled
substances.
toxicology
Toxicology testing should not be used in a ___ manner but should be used in the context of other clinical information to inform and improve patient care.
punitive
Toxicology screening for a class of drugs might not detect all drugs in that ___. For example, fentanyl testing is not included in widely used toxicology assays that screen for opiates as a class.
class
Recommendation 11
-Clinicians should use particular caution when prescribing ___ pain medication and ___ concurrently and consider whether benefits outweigh risks of concurrent prescribing of opioids and other CNS depressants.
opioid, benzodiazepines
Recommendation 12
-Clinicians should offer or arrange treatment with ___-based medications to treat patients with opioid use disorder.
evidence
When determining dosing:
rule 1: do not use an online __
rule 2: use a reliable equianalgesic dosing chart
rule 3: ___ work multiple times
calculator, check
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