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Fluticasone/salmeterol (Advair)
contains corticosteroid and bronchodilator
Long acting agonist that promotes relaxes smooth muscle over 12 hours.
NOT an emergency drug for asthma.
education: after inhalation, rinse mouth with water without swallowing (reduce risk of candidiasis), avoid smoking, and receive pneumococcal and flue vaccines if there is a risk of infection.
Albuterol, Atrovent, Ipratopium, & sole-medrol
rescue asthma drugs
Albuterol & Atrovent: short acting beta agonist
Ipratopium: anticholinergic agent
solu-medrol: steroid to control underlying inflammation (not immediate)
Admin Q20 mins
NORMAL to habe tremors and palpitations
Capasaicin (Zostrix)
over the counter analgesic used for minor pain.
Education: wait at least 30 mins after massaging cream into hands before washing them to ensure adequate absorption, avoid contact with eyes, nose, and mouth (contains pepper contents), wear gloves when applying, avoid HEATING pads (vasodilation increases absorption and can cause a chemical burn), NORMAL to have burning, stinging, or erythema and will subside in a week, and can be used with tylenol or nonsterodial anti-inflammatory drugs to effectively treat osteoarthritis pain.
Use regularly (3-4x/day)for week to months.
Montelukast (singulair)
given with beta agonist and steroid (fluticasone or budesonide) to provide long term asthma control
Tobramycin
antibiotic
mostly used with aerosolized form to treat CF exacerbation when Pseudomonas is the predominant organism causing the lung infection
Rifaximin
antibiotic
used with hepatic enceph r/t to increased ammonia levels.
Meperidine (Demerol)
Opioid
CONTRAindicated in sickle cell r/t large frequent doses that can cause toxic metabolite (tremors -> seizure)
Most effective PCA
morphine or hydromorphone (Dilaudid)
Clopidogrel (PLavix)
antiplatelet
Naproxen (Naprosyn)
NSAID
Ginko Biloba
can increased risk for bleeding!
Vancomycin
antibiotic
Nephrotoxic (BUN and creatinine) , monitor trough levels before the 4th dose (15-20),
Promethazine
antiemetic
Duloxetine (Cymbalta)
serotonin-noreip reuptake inhibitor
Used: antidepressant and pain-relieving effect for fibromyalgia
Amitriptyline (Elavil)
Tricyclic antidepressant
use: antidepressant and pain relief for fibromyalgia
Pregabalin
tricyclic antiD
use: depression and fibromyalgia
Isotretinoin (accutane)
Acne medication
NEED TWO negative pregnancy test before starting medication
Educate: use two forms of brith control
Can NOT donate blood for at least one month to ensure preggos do not receive donation
Pregnancy X category
Lithium
mood stabilization to treat bipolar
Worry about the D's:
Dehydration, Decreased NA diet (increase NA in diet) , Decreased renal fnx (elderly), and Drug interactions (Diuretics (thiazide) and NSAIDs)
therapeutic level is NARROW (0.6-1.2) >1.5 is REPORTABLE
LOOK OUT FOR : ataxia, confusion,agitation, neuromuscular excitability, and DI (polyuria and polydipsia)
Phenytoin (dilantin)
Anticonvulsant
provide good ORAL CARE to prevent gingival hyperplasia (no reason to d/c)
d/c: fever, skin rash, and lymphadenopathy
risk for gait disturbance
Death Rattle treatment
Anticholingeric (atropine) OR Scopolamine patch
Dries up secretions that dying patient can no longer manage on their own.
Helps comfort the family
Ondansetron (Zofran)
antiemetic
Omeprazole (Prilosec)
PPI decreases stomach acid production
risk for long term use:
decrease bone density (r/t decrease intestinal calcium absorption) -> increased risk of fractures
decrease in acid production increases risk for pneumonias and c.diff
Prasugrel (Effient)
antiplatelet
Ace inhibitors, isotretinoin, and doxycycline
NO for preggos
Ace: bad for fetal kidney development
Isotretinion: major birth defects
Doxy: impair bone maturation of fetus.
Hydrochlorothiazide
thiazide diuretics
NO with lithium
used: HTN
SE: low K (muscle cramps) , low NA (mental status and seizures), high uric acid(worsen gout attacks), and hyperglycemia.
chlorthalidone
thiazide diuretics
no with lithium
SE: low K (muscle cramps and cardiac effects) low NA (mental status and seizures), high uric acid (worsen gout attacks) and hyperglycemia
Torsemide
loop diuretic
Bumetanide
loop diuretic
SARTANS
losartan, valsartan and candesartan
angiotension II receptor blockers
USED with patient who can not take ACE inhibitors or have adverse reactions to ACE inhibitors
V fib
EMERGENCY
CPR and dfib
just a bunch of up downs
Afib
irregularly irregular
GOAL of treatment is to lower ventricular rate <100
CCB, BB, and dig
V tach
no p waves and WIDE QRS
SVT
NARROW QRS
admin adenosine FAST (half life <5 seconds) can be given twice
should be given in the AC IV site
NORMAL to have period of ASYSTOLE!
PVC
wide and distored QRS and rhythm is all over the place
Serious complication of tonsillitis or pharyngitis
pertonsillar or retropharyngeal abscess
LOOK for: pot potato or muffled voice, trimus (inability to open mouth), pooling of saliva, deviation of uvula to one side.
#1 MAINTAIN AIRWAY
Dextromethorphan
cough suppressant
Lead poisoning
lead levels >5
Chelation therapy needed
education: home searched for lead sources, wash children hands frequently, increased intake of iron and vit C, hard surfaces should be wet dusted or mopped weekly, use COLD water to cook if pipes are source of lead.
Kawasaki Disease
lymph node syndrome
characterized by >5 days of fever, conjunctivitis, splenomegaly and extreme swelling.
#1 CONCERN: cornonary artery aneurysms -> MI and death
tX: IVIG with aspirin to prevent heart disease
education: CPR to parents, REPORT fever!! irritability is common for first 2 month, ROM and warm baths to prevent stiffness
Lactolose
Not digested or absorbed until it reaches large intestine
Produces an acidic environment and hyper osmotic effect
Education: can be given with water, juice or milk to improve flavor, can be administered as an enema, for faster results is can be administered on an empty stomach
THERAPEUTIC effects: 2-3 soft stools/day, improved mental status, and no dehydration, hypernatremia, or hypokalemia
Oxybutynin (Ditropan)
anticholinergic
tx: overactive bladder
S/sx: Cant eat, pee, shit, or spit, heat intolerance, blurred vision, and drowsiness
CVP
2-8
measures right ventricular preload and reflects fluid volume status
PA catheter use the blue (right proximal port)
low CVP: hypovolemia
High CVP: right ventricular failure or fluid volume overload
CVP is measured as a mean pressure and should be recorded at the end of expiration.
Wedge pressure
Use distal port of PA catheter
Nifedipine (Procardia)`
CCB
Pneumothorax chest tube on water seal suction
intermittent bubbling consistent with respirations (due to escaping from the pleural space) is expected until the lung has fully expanded
Water seal
NO continuous bubbling = air leak
bubbling with forceful cough or expiration is fine
water should rise and fall with respirations
Dry suction
NORAML to have gentle bubbling
chest tube chamber hooked to low wall suction setting
Medications before Dialysis
HOLD: antiHTN water soluble vits (B & C), antiB and dig
GIVE: CA ACETATE r/t high phosphorus levels that dialysis can not filter out either
Lispro insulin r/t fast acting and need to be given 15-30 mins before meals
FAT soluble vitmins (ADEK) not affected by dialysis
Epiglottis
life threatening
r/t HiB vaccination
s/x: tripod positioning, high grade fever, severe sore throat, followed by 4 D's: DROOLING, DYSPHONIA, DYSPHAGIA, and DISTRESSED AIRWAY (inspiratory stridor)
Education: Do NOT ask to open mouth it will occlude airway
nitrazine pH test
amniotic fluid is alkaline: blue-green or blue-gray = positive
Vaginal fluid is acidic: yellow or olive green = negative
Systemaic Lupus Erythematosis (SLE)
autoimmune disease that affect connective tissues
BUTTERFLY RASH across cheek and bridge of nose
s/sx: nephritis, arthritis, and vasculitis
Pyloris Stenosis
hypertrophy of the pylorus -> stenosis of the passage between the stomach and duodenum
s/sx: evident 2-8 weeks after birth. occasional vomiting -> forceful projectile vomiting.
dehydration and lyte imbalances.
Palpate the pyloric muscle and confirmed through ultrasound
how many calories burn loose a pound
3500
Cyclophosphamide
immunosuppressant and chemo agent
common SE: hemorrhagic cystitis (bladder inflammation)
education: drink fluids, IV hydration, and mesna therapy
St. Johns Wart
antidepressant herbal supplement
education: do NOT take with tricyclic, MAOI, SSRI/SNRI
-> increase side effects and lead to serotonin syndrome
Serotonin Syndrome
mild: shivering and diarrhea
severe: muscle rigidity, fever, and seizures
Increased ICP in infant
sunset eyes (sclera visible above the iris)
wide bulging fontanelle, prominent scalp veins, increased head circumference
normal output for infant
2ml/kg/hr
6-10 diapers/day OR 1 diaper/4hours
COPD levels and common dx
SAt: 90-93%
Pao2: 60-70
polycythemia
body tries to compensate by creating more RBC for o2 carrying capcaity
Terazosin
Alpha-adrenergic blocker
tx: relieve urinary rentention in clients with BPH
education: ortho hypotension, admin at bedtime, avoid erectile dysfunction medications that can bottom out BP
Sildenafil
viagra
no nitro or trazosin r/t bottoming out BP
NO grapefruit juice
CCB
no GRAPEFRUIT JUICE
MAP
>60 for adequate perfusion
Normal: 70-105
Duchenne Muscular Dystrophy
2-5 years old
Lower extremities affected first
Gower signs: use of hands to rise from squat or from chair to compensate for weak lower muscles
Wheelchair bound and die by 20-30 y/o
education:
prevents falls, exercise with swimming nothing more strenuous,
Coumadin and Heparin
Need 5 day overlap before switch from hep to coumadin
this ensures coumadin to reach therapeutic level before d/c of hep.
PTT>100 is criteria for D/C
Coumadin: no grapefruit or cranberry juice or green tea.
Avoid vit K NOT POTASSIUM VIT K!!!
ASthma triggers
tobacco smoke, beta blockers, aspirin, and NSAIDs
URI are #1
molds, pollen, dust mites, cockroaches, and animal danger
Rheumatic Fever
#1 questions: have you recently had strep
2-3 weeks post infix
s/sx: joint arthritis, carditis, subQ nodules, fever, prolonged PR intervals, increased sedimentation rate
CAN LEAD TO mitral regard/stenosis
Tx: penicillin
Levetiracetam (Keppra)
treats seizures
methotrexate (Rheumatrex)
immunosuppressant
tx: RA and psoriasis
s/sx: bone marrow suppression, increased risk for infection,
education: avoid large groups, people with infections, receive inactivated vaccines (flue and pneumococcal) NO live (herpes voter)
NO preggos, and NO ETOH r/t hepatotoxic side effects
Hydroxyxholoroquine (Plaquenil)
Antimalarial
Eye checked Q 6months r/t possbile retinal damage
Palidermin (Kepivance)
human growth factor
prevents oral mucositis in patietns dx with hematologic malgiance
Cane walking
hold can on stronger side
ascending stairs: first step with stronger leg, next bare weight on stronger leg, move cane, and finally step with weaker leg
potty training
18-24 months
ability to communication and follow directions
Promethazine (Phenergan)
Antiemetic
Do NOT use IV-- can cause damage to tissues including necrosis and gangrene
IM is the preferred rout
Tumor Necrosis Factor drug
Infliximab, adalimumab, and etanercept
suppress the inflammatory response in autoimmune disease such as RA, crohn and psoriasis
education: Do NOT take these drugs if you have a current, recent, or chronic infection, need a TB skin test Q year, only get INACTIVE vaccines (flu and pneumo)
Bishop Score
Score for induction of labor
Score cervix 0,1,2,3
Score of >8 = induction of labor
Steroids
increase blood sugar (increase insulin dose for Dm)
Increase risk of peptic ulcer with NSAIDS
start at a high dose and then slowly tapper to reduce the risk of sudden adrenal crisis
Can cause fluid retention and worsening HTN
Pericarditis
Normal: pain with deep inspiration, ST elevation (not MI), and friction rub heard on auscultation.
NOT normal: cardiac tampanda s/s JVD and distant heart sounds, and decreased BP
Hirschsprung Disease
newborn with missing nerve cells of distal bowel
s/sx: no peristalsis and stool is passes, distended abdomen and will not pass meconium within 24-48hours, vomit GREEN BILE,
tx> surgical removal of defective bowel and colostomy is required
REPORT: increasing abdominal girth and foul-smelling diarrhea and fever
Sulfa AntiB
tx: RA and ulcerative Colitis
MOA: inhibits production of prostaglandins in body
SE: Crystaluria-- kidney injury EDU: drink 8 glasses of water and maintain output 1200-1500ml/day
photosensitivity-- sunscreen and avoid sun
Folic acid deficiency-- eat folate rich food and take 1mg folic acid sup
agranulocytosis (leukopenia)-- monitored for CBC at start of therapy and report fever or sore throat ASAP
Steven-johnson-- DC is rash develops
EDU: pee with turn orange-yellow this is NORMAL
Trendelenburg
mod trendelenburg
TREN: head up ass down (crany)
mod tren: head down ass up (shock)
Bowel Irrigation for colostomy
fill irrigation container with 500-1000ml of luke warm water, flushing irrigation tubing, and reclamp.
hang the container on a hook to IV pole
instruct patient to sit on toilet, place the irrigation sleeve over the stoma, extend the sleeve into the toilet and place place irrigation container approximately 18-24 in above the stoma
lub the cone tipped irrigator, insert the cone and attach catheter gentle into stoma and hold in place
slowly open the roller clamp and allow irrigation solution to flow for 5-10 mins
clamp the tube if cramping occurs and until it subsides
once the desired amount is instilled, the cone is removed and feces are allowed to drain through the sleeve into the toilet.
IRRIGATION allows for regulated bowel regimens
Lef to right shunting heart defects
(Patent ductus arteriosus, artial septal defect, and ventricular septal defect)
pulmonary congestion
increased work to breath and decrease lung compliance
increase RR, HR, and metabolic rate (poor wt. gain) diaphoresis during feeding, heart murmur and signs of congestive heart failure
Right to left shunt heart defects (yet, transposition)
cyanotic defects
clubbed fingernails or cyanosis with crying
NSAID long term use
can cause MI, stroke, HTN, and possible heart failure!
decrease diuretic and Bp medication effect!
Increase chronic kidney disease and peptic ulcer
Thiazoildinediones (GLITAZONE)
tx: type II DM
improves insulin sensitivity but does NOT release excess insulin
NO NO for heart failure or volume over load!
increase risk for bladder cancer
HbA1c goal
<7
Isoniazid (INH)
TB med
Hepatotoxic and peripheral neuropathy
NO ETOH, take vit b6 (prevent neuropathy), NO alum-containing antacids, Report changes in vision, numbness or tingling in extremities, and yellowing of skin,
Rifampin
TB med
body fluids will turn orange-red
Black Cohosh
tx: menopausal hot flashes
can cause thickening of the uterine lining and potential liver toxicity
Ginko, ginger, garlic, and ginseng (all start with g)
increase risk of bleeding
Metoformin (Glucophage)
NO before CT and 48 hours after r/t kidney injury
Low pressure alarm for an art line
#1 check for bleeding at the tube connection
low pressure indicates hypotension
excessive chest tube drainage for adults and children
>100ml within first hour
>5-10ml/kg/hr with children
tinea corporis
ringworm
contagious
tx: antifungals (tolnaftate, haloprogin, miconazole, and clotrimazole)
Scerloderma
overproduction of collagen that causes tightening and hardening of the skin and connective tissue
progressive disease without a cure
tx: managing s/sx
#1 concern is renal crisis that causes malignant HTN due to narrowing of the vessels that provide blood to the kidneys
s/sx: Raynauds phenomenon (blue and cold finger tips), pulmonary fibrosis (dry cough and dyspnea), heartburn, and dysphagia.
Guillain- Barre
acute immune-mediated polyneuropathy
GOLD SIGN: ASCENDING muscle paralysis and absence reflexes.
#1 concern: neuromuscular respiratory failure (rate and depth of RR) GOLD STANDARD TEST: spirometry
s/sx: ortho hypotension, paralytic ileus, urinary rentention, diaphoresis, absent reflexes (including gag), CN II, III, IV, and VI abnormal.
1kg= __mL of fluid
1kg=1,000ml
fifth disease
SLAPPED FACE
viral illness that affects SCHOOL AGED
spread via respiratory secretion MOST communicable before onset of s/sx.
GOLD SIGN: SLAPPED face (rash on cheeks) spread to extremities and maculopap. rash develops from prox. to distal surfaces.
s/sx: fatigue and joint pain (ibuprofen) ONCE symptoms develop they are no longer infectious.
recover with 7-10 days
biphosphonate
alendronate risedonate
RISK for jaw necrosis
educate: drink a lot of water with med admin and sit up for at least 30 minutes
late decels
uteroplacental insufficiency
1.give o2 by facemask
2.reposition on right or left side
3.oxytocin stopped
4. provide IV bolus
prepare for deliver is decelerations persist