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Lipids are defined as
Organic substances insoluble in water but soluble in organic solvents such as ether and chloroform
Distribution of lipids
Lipids are widely distributed in both animals and plants
Animal sources of lipids
Fats, butter, egg yolk, cream, liver, and brain
Plant sources of lipids
Nuts, peanuts, olive, olive oil, cotton seed oil, sunflower oil, and linseed oil
Energy value of lipids
1 gram of lipids provides 9.3 kcal
Dietary importance of lipids
Provide high energy, essential fatty acids, and fat-soluble vitamins (A, D, E, K)
Structural roles of lipids
Components of the nervous system and cell membranes
Lipids forming the lipid bilayer
Phospholipids, sphingolipids, and cholesterol
Functions of depot fat
Stored energy, heat insulation, and protection of internal organs
Why lipids are efficient energy stores
Higher specific energy than glycogen or protein
Consequence of storing energy as glycogen instead of fat
Would require approximately doubling of body mass
Extracellular lipid signaling molecules
Steroid hormones synthesized from cholesterol
Eicosanoid origin and examples
Derived from C20 polyunsaturated fatty acids and include prostaglandins, thromboxanes, and leukotrienes
Intracellular lipid second messengers
Derived from breakdown of phosphatidylinositol-4,5-bisphosphate (PIP2)
Main classification of lipids
Simple lipids and compound (conjugated) lipids
Definition of simple lipids
Esters of fatty acids with various alcohols
Types of simple lipids
Neutral fats and waxes
Definition of neutral fats
Esters of fatty acids with glycerol
Definition of waxes
Esters of fatty acids with alcohols other than glycerol
Definition of compound (conjugated) lipids
Esters of fatty acids with a non-lipid component
Types of compound lipids
Phospholipids, glycolipids, and lipoproteins
Composition of phospholipids
Lipids and phosphoric acid
Composition of glycolipids
Lipids and carbohydrates
Composition of lipoproteins
Lipids and proteins