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gene products
proteins, functional RNAs
gene expression
process by which a gene produces its product and the product carries out its function
ontogeny
the process by which an individual changes in the course of its lifetime - that is, grows up and grows old
central dogma of molecular biology
information is transferred from DNA to RNA to protein
DNA
provides a blueprint that codes for RNA
evolutionary genetics
examine how DNA leads to evolutionary change by comparing sequence variation among species or individuals that exhibit different traits
functional genomics
Study of gene functions and interactions. they compare gene or protein expression in people or species that exhibit different traits
mRNA
A type of RNA, synthesized from DNA, that attaches to ribosomes in the cytoplasm and specifies the primary structure of a protein.
transcription (RNA synthesis)
process of using a DNA template to create a strand of RNA
translation (protein synthesis)
process by which the sequence of bases of an mRNA is converted into the sequence of amino acids of a protein
polypeptide
long chain of amino acids that makes proteins
transcriptome
technology analyzing the activity of a few thousand genes at a time in particular tissues, enabling researchers to analyze all of the mRNA being expressed in a given tissue at a given time point
genome
all of an organism's genetic material
forward genetics
identified the genes associaed with a given phenotype
reverse genetics
seeks to determine which phenotypes arise from as a result of a particular genetic sequence
histones
other proteins influence gene expressed by altering the chemical properties of DNA or protein structures upon which DNA is wound
epigenetic modification
Changes in gene expression without altering DNA sequence.
histone modifications
Chemical changes to histones affecting gene expression.
DNA methylation
The addition of methyl groups (—CH3) to bases of DNA after DNA synthesis; may serve as a long-term control of gene expression.
evo-devo approach
developmental mechanisms also have an evolutionary history that can be described as a series of modifications of ancestral patterns and its reconfiguration into a modern attribute
A "tool Kit" for how things are written to develop. How the brain develops is very important. Develops longer = bigger. But in right places
phenotypic plasticity
the ability of an organism to change its phenotype in response to changes in the environment.
polyphenisms
a special type of phenotypic plasticity where discrete phenotypes arise from a single genotype
supergene
a region of DNA containing many linked genes that influence a behavioral phenotype
epigenetics
the study of environmental influences on gene expression that occur without a DNA change
Niko Tinbergen
worked on begging behavior in herring gulls, goose perceptual mechanism that is sensitive to visual cues provided by egg shaped objects
ethology
the first discipline dedicated to the study of both proximate and ultimate causes of animal behavior
an instinct
innate behavior defined as a behavior pattern that appears in fully functional form in response to a stimulus, even if they had no prior cues
releaser
stimulus that triggers a specific behavior (neural network responsible for detecting the simple cue)
fixed action potential
innate behaviors following regular pattern (ex. fish defending territory from something with red backside)
innate releasing mechanism
a built in biological process that triggers a specific behavioral response to a stimulus (ex: when a dog sees a cat running away from them, they have an instinctive response to chase the cat)
kenneth Roeder
nocturnal insects must face strong selection pressure to detect bat sounds and avoid them
action potential
a neural impulse; a brief electrical charge that travels down an axon (is the signal one neuron uses to communicate with another)
what happens when an action potential arrives at the end of an axon
it may cause the release of a neurotransmitter, a chemical signal that diffuses across the narrow gap or synapse
synapse
the junction between the axon tip of the sending neuron and the dendrite or cell body of the receiving neuron
interneurons
neurons within the brain and spinal cord that communicate internally and intervene between the sensory inputs and motor outputs (relay signals between them)
command centers
A neural cluster or an integrated set of clusters that has primary responsibility for the control of a particular behavioral activity.
optogenetics
a group of techniques that can be used to study neural mechanisms of behavior in intact animals (uses light)
ultaviolet light (UV)
animals use it to find food, attact mates, or navigate great distances
circadian clock
An internal timing mechanism that is capable of maintaining daily cycles of physiological functions, even when there are no temporal cues from the environment
central pattern generator
neural circuitry that is responsible for generating the rhythmic pattern of a behavior such as walking (well studied in invertebrates)
stimulus filtering
ability of neurons to filter out information and focus on biologically relevant stimuli
endogenous clock hypothesis
animals have a biological clock with a built-in schedule (that acts independently of any cues from the animal's surroundings) to control changing priorities
environmental stimulus hypothesis
animals use feedback from the surrounding environment to change priorities over time
free running cycle
The cycle of activity of an individual that occurs in the absence of environmental cues
circadian rhythm
the biological clock; regular bodily rhythms that occur on a 24-hour cycle
entrain
resetting and matching a clock to an environmental cycle or changes through the influence of a zeitgeber
zeitgeber
stimulus that resets the circadian rhythm
suprachiasmatic nucleus (SCN)
A small brain structure that uses input from the retina to synchronize its own rhythm with the daily cycle of light and dark; the body's way of monitoring the change from day to night.
circadian pacemaker
the "master control" for a person's various circadian cycles, consisting of a group of neurons forming the suprachiasmatic nuclei of the hypothalamus
melatonin
a hormone prduced at night and modulates sleep and circadian rhythms
circannual rhythm
behavioral rhythms linked to the yearly cycle of seasons
Photoperiod
the period of time each day during which an organism receives light; day (24hr) length
Seasonal rhythms are driven by day length
photosensitivity
sensitivity to light
opportunistic breeding
reproduction is triggered by unpredictable environmental cues, such as rainfall or food availability rather than a fixed breeding season
luteinizing hormone
a protein that stimulates production from the pituitary gland, which may cause the testes to produce testosterone
HPG axis
Hypothalamus-pituitary-gonad axis, the negative feedback loop that regulates sex-hormone production.
- These reproductive hormones, which starts in the hypothalamus with the release of gonadotropin-releasing hormone
HPA axis
Interaction between the nervous and endocrine systems to produce the body's response to stress. Long periods of high levels of glucocorticoids can impair immune function, cause sickness
acute stressors
sudden, one time events; can directly and rapidly affect an animals behavior through the release of glucocorticoids
- the predatory hawk + unexpected snowstorms
chronic stressors
sources of stress that occur continuously or repeatedly; sources of continued and often long term activation of the HPA axis
- If severe weather or food limitation become prolonged, chronically elevated glucocorticoids can have negative physiological effects
Intron
sections of mRNA that do not code for proteins
Exon
sections of mRNA which become "expressed" or translated into a protein
- spliced with other exons into a long chain of mature mRNA
domestication syndrome
non-target traits developed in addition to the selected ones
Polymorphism
is a variation in gene sequence that has become established in the population
what can a mutation change?
the functionality of a gene, how much a gene is expressed, where a gene is expressed, when a gene is expressed
krogh's principle
for such a large number of problems there will be some animal of choice, or a few such animals, on which it can be most conveniently studied
interaural level difference
loudness of the sound and difference in sound intentsity between the ears
interaural time difference
difference in time latenct between the ears, difference in time it gets to your right and left ear
infrasound
Sounds with frequencies below the human range of hearing
ultrasound
sound frequencies above human hearing
Ipsilateral
same side (closer to sound)
Contralateral
other side (farther away)
circalunar
syncronized with the moon
diel
24 hr daily rhythm
Infradian
rhythm longet than 24 hrs
ultradian
rhythms shorter than 24 hrs
Circatidal
rhythms sychronized with tides (every 13 hrs)
pineal gland
secretes melatonin
Homeostasis
A tendency to maintain a balanced or constant internal state; the regulation of any aspect of body chemistry, such as blood glucose, around a particular level
general adaptive syndrome
what happens when you are having a stress response and can't get away from the stressor
-Alarm reaction: stress respond begins
-Resistance: coping w stressor
-Exhaustion: onset of stress pathology; something bad is happening and can lead to death