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endocarditis
An infection of the inner lining of the heart, typically involving the heart valves, caused by bacteria or other pathogens.
stenosis
causes increases PRESSURE in UPSTREAM chamber, thick and stiff if VENTRICLE
rheumatic heart disease
A condition resulting from rheumatic fever (STREP) that affects the heart valves and can lead to heart failure.
rheumatic heart disease
leading cause of cardiovascular death in people under age 50
no
is it okay to use cephalexin if a patient has a SEVERE reaction to penicillin
monotherapy (1 medication)
medication treatment of stage 1 hypertension
regurgitation
causes increased VOLUME in UPSTREAM chamber, DILATED
strep veridans
common bacteria of infective endocarditis from dental procedures that affects the LEFT SIDE
poor blood flow, poor wound healing, difficult infections
dental complications of hypertension
mitral
most common valve affected by IE (infective endocarditis) for non-needle users, MOST SUSCEPTIBLE to vegetations
tricuspid
valve most often affected by infective endocarditis in IV DRUG USERS, typically associated with right-sided heart infections
staph aureus
common bacteria of infective endocarditis from IV drug use that affects the RIGHT SIDE
prophylactic antibiotics
what would patients with history of heart lesion or repair likely require
stage 1
stage of hypertension where Bp is : 130-139/ 80-89
cyanotic defects
shunt of blood flow that results in an increase in deoxygenated blood supply to the body, right to left
VSD, ASD, patent ductus arteriosus
examples of acyanotic defects
acyanotic defects
congenital heart defects that DO NOT significantly reduce blood oxygen levels, LEFT-RIGHT
stage 2
stage of hypertension where Bp is : >140/ >90
smoking, diabetes (poorly controlled), medications (ACE and Retin)
risk factors (during pregnancy) for congenital heart failure other than genetic
ventricular septal defect, atrial septal defect, patent ductus arteriosus
3 types of congenital heart defects that result in shunting?
infection
most common cause of endocarditis
thrombus, bacteria, and fibrin/platelets form vegetation
how does endocarditis form after valvular damage
prosthetic heart valve, rheumatic heart disease, IV drugs, immunocompromised
what patients are at increased risk of endocarditis
potential medication reactions
why would you not give patients antibiotics “just in case”?
strep viridans and staph aureus
what bacteria have a high risk of causing endocarditis in patients with predisposing conditions
FEVER (unexplained), embolic spots (palms and soles) ect.
what are the symptom of endocarditis
fever
most common symptom of endocarditis
blood culture, echos (transthoracic and transesophageal)
test used to diagnose bacterial endocarditis
6 weeks
What is the duration of treatment (IV antibiotics) for endocarditis?
antibiotics and/or surgery
treatment options for endocarditis
100%
what is the mortality rate of endocarditis without treatment
Prosthetic heart valve, prior endocarditis, unrepaired cyanotic CHD, recently repaired CHD, incompletely repaired CHD
Who needs to get antibiotic prophylaxis before dental cleaning to prevent infective endocarditis patients at high risk
no longer recommend prophylaxis for moderate risk individuals
how have endocarditis prophylaxis guidelines changed
stenosis
a narrowing of a blood vessel or heart valve that restricts blood flow
regurgitation
the backward flow of blood through a heart valve due to improper closure
yes stage C asymptomatic severe
Can a person have heart valve disease and have no symptoms?
aortic and pulmonic (regurgitation and stenosis)
types of CONGENITAL valvular diseases
degenerative, rheumatic, infection
ACQUIRED causes of valvular diseases
balloon valvuloplasty
A minimally invasive procedure used to treat heart VALVE STENOSIS, where a balloon is inserted and inflated to widen the valve opening.
LV during diastole
where and when does the backflow of blood go in aortic regurgitation
LA during systole
where and when does the backflow of blood go in mitral regurgitation
valve degeneration, infection, and congenital defects.
Potential causes of valvular regurgitation
aortic stenosis
causes left ventricle to thicken and become stiff
aortic regurgitation
causes left ventricle to stretch and become floppy
mitral valve prolapse, rheumatic infective MAC
primary causes of mitral regurgitation
ischemic CM, dilated CM, hypertrophic CM, Afib
secondary causes of mitral regurgitation
congenital heart defects
common cause of pulmonary valve stenosis
RA
What chamber gets dilated in tricuspid regurgitation?
rheumatic, calcific (degenerative), bicuspid (congenital)
typical causes of AORTIC STENOSIS
left ventricle thickens
change in heart during AORTIC STENOSIS
left atrium, dilates
change in heart during MITRAL STENOSIS
left ventricle dilates
change in heart during AORTIC REGURGITATION
left atrium dilated
change in heart during MITRAL REGURGITATION
rheumatic (RHD)
common cause of MITRAL STENOSIS
trauma, rheumatic (RHD), congenital (bicuspid), age/infection
common causes of AORTIC REEGURGITATION
congenital heart disease
most common type of major birth defect
blood bypasses the lungs
how does fetal circulation differ from circulation after birth?
foramen ovale and ductus arteriosus
what structures change after birth
shunt
aortic or vascular communication that allow mixing of oxygenated and deoxygenated blood
atrial septal defect
a congenital heart defect characterized by an abnormal opening in the atrial septum, allowing blood to flow between the left and right atria.
left to right
direct of blood flow through most shunts after birth
if right ventricle is stiff (pulmonary hypertension)
when would direction of blood flow through shunt change to right→left
ventricle septal defects
most common type of shunt
RA and RV dilation, exercise intolerance, arrhythmias (atrial), right heart failure, (pulmonary arterial hypertension rarely)
consequences of left to right unrepaired atrial septal shunt/defect
LA and LV dilation, left heart volume overload, pulmonary arterial hypertension
consequences of unrepaired ventricular septal defect/shunt
pulmonary arterial hypertension
consequences of LARGE unrepaired ventricular septal defect/shunt
ventricular
which type of shunt/septal defect is more serious
patent ductus arteriosus
a condition where the ductus arteriosus fails to close after birth, leading to abnormal blood flow between the aorta and pulmonary artery
left heart enlargement, pulmonary hypertension
effects of patent ductus arteriosus
downstream resistance
what determines direction of flow between shunt
ventricular septal defect, over-riding aorta (drains L and R ventricle) , pulmonic stenosis, RV hypertrophy
features of tetralogy of fallot
right to left flow through ventricular septal defect
consequence of pulmonary stenosis in tetralogy of fallot
endocarditis (prosthetic heart valve)
risk associated with repair of tetralogy of fallot
coarctation of aorta
discrete narrowing in proximal descending aorta near ductus arteriosus
transposition of great arteries
a congenital heart defect where the aorta and pulmonary artery are switched, leading to two separate circulations.
no oxygenation of blood, leads to hypoxia and heart failure
why can transposition of the great arteries cause an infant to die quickly after the ductus arteriosus closes
none, asymptomatic
symptoms of hypertension
BP above 130/80
what classifies hypertension
primary hypertension
most COMMON type of high blood pressure WITHOUT KNOWN CAUSE (idiopathic), often linked to genetic factors, lifestyle, and environmental influences.
secondary hypertension
high blood pressure caused by an underlying condition, such as kidney disease or hormonal disorders.
uncontrolled and higher pressures
what worsens the complications of hypertension
diabetes and smoking
factors that exacerbate (worsen) hypertension
remodeling/ thickening of smooth muscle (tunica media)
impact of hypertension on vessels
LV hypertrophy, increase MI risk, heart failure
major CARDIAC complications associated with hypertension
ATHEROsclerosis
primary cause of coronary artery disease, acute coronary syndrome and peripheral artery disease
ARTERIOsclerosis
a condition characterized by the thickening and hardening of arterial walls, often associated with aging and hypertension.
stroke, dementia, vision issues, heart disease, chronic kidney disease, pregnancy complications
health problems caused by high blood pressure
lifestyle modification (exercise bm, smoking cessation, limit alcohol and sodium)
first line treatment of hypertension