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Parathyroid Hormone (PTH)
•Secreted by the parathyroid gland
•Increases formation and activation of osteoclasts, the principal bone-reabsorbing cells
•Stimulates reabsorption of Ca2+ from urine in the kidney, reducing the amount of Ca2+ excreted in the urine.
•Indirectly increases Ca2+ uptake from the small intestine through the activation of calcitriol.
Calcitonin
•Secreted from C cells in the thyroid gland when blood Ca2+ levels are too high
•Rapidly lowers blood Ca2+ levels by inhibiting osteoclast activity
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