Oxidation-Regulated Transcription Factors

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5 Terms

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What role does H2O2 play in transcriptional regulation?

Acts as a signalling molecule

2
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How are oxidative stress-responsive TFs regulated?

By oxidation-dependent mechanisms

3
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Which yeast transcription factor responds to H2O2?

Yap1

4
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What happens to Yap1 under oxidative stress?

It accumulates in the nucleus

5
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What genes does Yap1 activate?

Antioxidant genes