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Nuclear Medicine
Specialized area of radiology using radioactive materials to examine organ function and structure.
Radiopharmaceuticals
Radioactive materials used in nuclear medicine to examine a body's organ function and structure.
Radiology
Uses beams of radiation to produce images of body structures, primarily showing anatomy.
Nuclear Medicine
Uses radioactive materials ingested, injected, or inhaled to show organ function (physiology).
Nuclear Medicine Technologist
Prepares and administers radionuclides to patients and performs imaging procedures.
Radiation
Energy traveling through a vacuum or medium, ultimately absorbed by another body.
Ionizing Radiation
High-energy radiation that can ionize an atom upon colliding with it, emitting more radiation (e.g., gamma rays, X-rays).
Non-ionizing Radiation
Low-energy radiation (e.g., microwaves, radio waves, sunlight, thermal radiation).
Gamma Camera
Main equipment in Nuclear Medicine; does not contain radiation, and uses a collimator as its 'lens'.
Collimator
The 'lens' of the gamma camera in nuclear medicine.
Thyroid Scan
A common nuclear medicine procedure to assess the size and function of the thyroid gland.
Thyroid Scan Isotopes
Uses 131I or 99mTc-pertechnetate for imaging.
Normal Thyroid Size
Approximately 4x2cm, with 2 lobes connected by an isthmus.
Thyroid Scan Nodule Assessment
Detects if thyroid nodules are 'hot' or 'cold,' indicating hyper- or hypothyroidism.
Whole Body Iodine Scan
Checks the staging of thyroid cancer and detects metastasis.
Bone Scintigraphy
Bone scan using 99mTc MDP/HDP, useful in oncology planning and management.
Bone Scan Sensitivity
Can detect a 5% bone turnover.
Radiograph Sensitivity
Requires a 50% minimum mineral loss before a lesion is visualized.
Myocardial Perfusion Imaging
Detects and diagnoses coronary artery disease and assesses its functional significance.
Normal Stress Perfusion Study Risk
The risk of cardiac death and myocardial infarction in a patient with a normal stress perfusion study is < 1% annually.
Myocardial Ischemia
Narrowing of blood vessels in the heart.
Myocardial Infarction
Obstruction of blood supply to the heart, resulting in tissue damage.
PET
Positron Emission Tomography, used to assess tissue metabolism and function.
PET Uses
Establish if a patient is responsive to chemotherapy.
PET/CT
Combination of CT scanning and PET for better localization of lesions.
Scintimammography
Uses 99mTc-sestamibi to detect cancer cells in the breasts and axillae.
Scintimammography Indications
Used in patients with abnormal mammograms, dense breasts, and post-operatively.
Renal Scintigraphy
Evaluates perfusion, cortical, and excretory functions of the kidneys.
Hepatobiliary Scan (HIDA)
Uses hepatobiliary iminodiacetic acid to diagnose acute and chronic cholecystitis and biliary atresia.
HIDA Scan Uses
Provides information on post-surgical bile drainage and biliary leakage.
Lung Perfusion Scan
Used for the detection of pulmonary embolism.
V/Q Scan
Identifies ventilation-perfusion mismatch in the lungs.
Pulmonary Embolism Management
Management involves giving heparin to patients.
Radionuclide Therapies
Uses beta particles for therapeutic purposes.
Radioactive Iodine Treatment
Used for treating thyroid diseases via oral administration.
Radioactive Iodine Mechanism
Iodine goes directly to thyroid tissue and emits beta particles to shrink and normalize the gland.
Radioactive Iodine Indications
Used for hyperthyroidism and differentiated thyroid cancer.
Thyroid Cancer Metastasis Treatment
Radioactive iodine will spread to thyroid gland metastatic lesions to stop the spread.
Function vs. Structure
Nuclear medicine focuses more on function, while radiology primarily looks at structure.
Nuclear Medicine
Can help in diagnosing diseases and treating abnormalities such as thyroid cancer.
Nuclear Medicine
Often used for diagnosis and treatment.
Ionizing Radiation
Can ionize an atom upon colliding with it to emit more radiation.
Common Nuclear Medicine Diagnostic Procedures
Thyroid Scan, Whole Body Iodine Scan, Bone Scan, Myocardial Perfusion Imaging, PET, Scintimammography, Renal Scintigraphy, HIDA, Lung Perfusion Scan
Hypothyroidism/Hyperthyroidism
Can be detected by Thyroid Scan.
Metastasis
Can be detected by Whole Body Iodine Scan.
99mTc MDP/HDP
Used in Bone Scintigraphy/Scan.
Myocardial Ischemia
Narrowing of blood vessels.
PET Possibilities
Establish possibility of tumor especially in areas difficult to access.
99mTc-sestamibi
Used in Scintimammography to detect cancer cells in the breasts and axillae.
Acute and Chronic Cholecystitis, Biliary Atresia
Can be diagnosed with HIDA scan.