Drugs of Choice, Antidotes, plus other Pharma

Desmopressin

DOC for Diabetes Insipidus

Chlorpropamide

Diabetes Insipidus (if HRT is not an option)

Demecocycline

Antibiotic for SIADH (decreases ADH release)

Calcitonin

Hyperparathyroidism. Deposits Ca²⁺ back into the bone.

Aluminum Hydroxide (Amphojel)

Hypoparathyroidism. Antacid that works as a phosphate binder — off label effect.

Lugol’s Solution

Hyperthyroidism. Used to lessen the size and vascularity of the Thyroid Gland.

Aspirin and Salicylates

Contraindicated in hyperthyroidism because it increases the free thyroid hormone levels.

Levothyroxine

DOC for hypothyroidism

Antithyroid Meds (Propylthiouracil, Methimazole)

DOC for Hyperthyroidism

Insulin

DOC for Diabetes Mellitus

Thiazides

Best classification of diuretics for the treatment of hypertension

Epinephrine

DOC for angioedema caused by excessive use of ACE inhibitors

ACE Inhibitors

First line of drugs for hypertension

Digoxin Immune Fab (Digifab, Digibind)

Antidote of Digoxin

Protamine Sulfate

Antidote of Heparin

Vitamin K

Antidote of Warfarin

Nitroglycerin

DOC for Angina Pectoris

Epoietin Alfa

DOC for stimulating RBC production

Filgrastin

DOC for stimulating WBC production

N-Acetylcysteine

Antidote for Acetaminophen toxicity

Sodium Bicarbonate

Antidote for Aspirin toxicity

Aminocaproid Acid

Antidote for thrombolytic medications

Calcium Gluconate

Antidote for

1. Potassium Chloride (KCl) toxicity

2. Magnesium Sulfate toxicity

Deferoxamine

Antidote for Iron toxicity

Glucagon

Antidote for Beta Blocker toxicity

Andexanet Alfa

Antidote for excessive Direct-Acting Oral Anticoagulants (DOACs)

Prednisone

Most potent steroid

Dexamethasone

Steroid that can be used to lower ICPBe

Bethamethasone

Steroid used to increase lung surfactant in a fetus

Colchicine

DOC for reducing Gout pain. Also used to treat acute gout attacks.

Carbamazepine

DOC for Trigeminal Neuralgia. Analgesic for neuropathic pain

Baclofen

Muscle relaxant (DOC for muscle spasms)

Tensilon

Emergency DOC for Myasthenic Crisis

Atropine Sulfate

DOC for Cholinergic Crisis

Urecholine

DOC for urinary retention secondary to Multiple Sclerosis

Oxybutynin

DOC for urinary incontinence secondary to Multiple Sclerosis

Mannitol

Osmotic diuretic that’s the DOC for increased ICP

Metoclopramide

DOC for vomiting (in general)

Ondansetron

DOC for vomiting caused by chemotherapy

Calcium Gluconate

DOC for hyperkalemia-related cardiac arrhythmias

Aluminum Hydroxide

Best antacid for Kidney conditions

Sevelamer

DOC for treating hyperphosphatemia in AKI patients

Oprelvekin

DOC for stimulating platelet production

Vitamin B Complex

DOC used to counteract the neurologic side effects of Vincristine

Palifermin, Sucralfate, Amifostine

Triad of mucosal protectants used to treat Stomatitis

Mesna

Antidote for Cyclophosphamide toxicity

Tamoxifen

DOC for Breast Cancer

Cyanocobalamine

DOC for Pernicious/Vitamin B12 Anemia

Hydroxyurea

Prevents sickle cell crisis

Riluzole (Rilutek)

DOC for Amyotrophic Lateral Sclerosis. It is a glutamate antagonist.

Carbidopa-Levidopa

DOC for Parkinson’s Disease

Amantadine

DOC for dyskinesia caused by Carbidopa-Levidopa treatment

Latonoprost

DOC for Open-Angle Glaucoma. It is a topical prostaglandin.

Pilocarpine

DOC for Closed-Angle Glaucoma

Beta Blockers

Drug classification used to lower aqueous humor production in glaucoma patients

Sodium Fluoride

Ear drops used in Otosclerosis. Prevents bone growth.

Paxlovid

DOC for Covid-19

Doxycycline

Used as PrEP and PEP for Leptospirosis

Penicillin G Benzathine

DOC for Syphilis

Ceftriaxone (with either Azithromycin or Doxycycline)

Treatment for Gonorrhea

Nystatin

DOC for Oral Candidiasis (oral thrush)

Doxycycline

DOC for the seven day treatment of Chlamydia

Azithromycin

Single dose treatment for chlamydia