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Asthma
Chronic inflammatory airway disease characterized by reversible bronchoconstriction wheezing cough and dyspnea triggered by allergens or irritants
Chronic obstructive pulmonary disease (COPD)
Progressive airflow limitation due to emphysema and chronic bronchitis symptoms include chronic cough sputum production and dyspnea primarily caused by smoking
Emphysema
Destruction of alveolar walls leading to enlarged air spaces decreased surface area and impaired gas exchange often due to smoking
Chronic bronchitis
Chronic productive cough lasting more than three months for two consecutive years caused by airway inflammation and mucus hypersecretion
Bronchiectasis
Permanent dilation of bronchi caused by chronic infection or inflammation leading to cough with foul-smelling sputum and recurrent infections
Pulmonary fibrosis
Progressive scarring of lung interstitium causing restrictive lung disease symptoms include dyspnea dry cough and crackles on auscultation
Idiopathic pulmonary fibrosis
Chronic progressive fibrosing interstitial pneumonia of unknown cause presenting with exertional dyspnea and dry cough primarily affecting older adults
Sarcoidosis
Multisystem granulomatous disease of unknown etiology commonly involving lungs and lymph nodes causing cough dyspnea and bilateral hilar lymphadenopathy
Pneumonia
Infection of lung parenchyma causing fever cough sputum production and infiltrates on chest X-ray
Tuberculosis
Chronic granulomatous infection caused by Mycobacterium tuberculosis symptoms include cough weight loss night sweats and hemoptysis
Pulmonary embolism
Sudden obstruction of pulmonary artery by thrombus causing sudden dyspnea chest pain and hypoxia often arising from deep vein thrombosis
Pneumothorax
Accumulation of air in pleural space causing sudden chest pain and dyspnea with decreased breath sounds on affected side
Pleural effusion
Excess fluid in pleural space causing dyspnea decreased breath sounds and dullness to percussion
Acute respiratory distress syndrome (ARDS)
Severe inflammatory lung injury causing diffuse alveolar damage hypoxemia and respiratory failure often following trauma or sepsis
Pulmonary hypertension
Elevated pulmonary artery pressure leading to right heart strain dyspnea fatigue and syncope
Cystic fibrosis
Genetic disorder causing thick mucus secretions lung infections and pancreatic insufficiency due to CFTR gene mutation
Alpha-1 antitrypsin deficiency
Genetic disorder causing early-onset emphysema due to lack of protease inhibitor protecting lung tissue
Hypersensitivity pneumonitis
Immune-mediated lung inflammation caused by inhaled organic antigens resulting in cough dyspnea and fever
Silicosis
Pneumoconiosis caused by inhalation of silica dust leading to nodular lung fibrosis and increased tuberculosis risk
Asbestosis
Interstitial fibrosis caused by asbestos exposure presenting with dyspnea and restrictive lung disease
Lung cancer
Malignant tumor often presenting with cough hemoptysis weight loss and chest pain
Small cell lung cancer
Aggressive neuroendocrine tumor strongly associated with smoking causing early metastasis and paraneoplastic syndromes
Non-small cell lung cancer
Includes adenocarcinoma squamous cell carcinoma and large cell carcinoma often presenting with cough and hemoptysis
Pleural mesothelioma
Malignant tumor of pleura associated with asbestos exposure causing chest pain and pleural effusion
Acute bronchitis
Inflammation of bronchi usually viral causing cough with sputum and wheezing
Respiratory syncytial virus (RSV) infection
Common cause of bronchiolitis in infants presenting with cough wheezing and respiratory distress
Bronchiolitis
Inflammation of small airways in infants causing wheezing and difficulty breathing
Pulmonary edema
Accumulation of fluid in alveoli causing dyspnea crackles and frothy sputum often due to heart failure
Pneumoconiosis
Lung diseases caused by inhalation of inorganic dusts leading to fibrosis and restrictive lung disease
Idiopathic pulmonary arterial hypertension
Progressive increase in pulmonary arterial pressure causing dyspnea fatigue and right heart failure
Acute bronchopulmonary aspergillosis
Hypersensitivity reaction to Aspergillus leading to asthma exacerbations and pulmonary infiltrates