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Glial Cells (neuroglia)
help support neurons (structure, nutrition, etc) ex. schwaan cells
Neurons
basic building block of nervous system
Dendrites
receiving incoming messages (from other neurons)
Cell body (soma)
contains the nucleus (Cell’s life support center)
Nucleus
make the decision to fire or not fire
Myelin Sheath
fatty tissue that insulates axon, speeding up transmission of messageno
node of ranvier
space between myelin sheath
axon
longest part of the neuron which the electric message travels the length of
schwaan cells
non-neuron cells in the CNS that form the myelin sheath
axon terminal buds (terminal branches)
end point of a neuron that releases neurotransmitters into the synapse, hence sending the message on to the next neuron
resting potential
when a neuron is not firing, has a negative charge with mostly potassium ions inside and mostly sodium ions outside
Polarization
at resting potential, when sodium is on the outside, potassium is on the inside of a neuronac
action potential
“nerve impulse” - causes the neuron to fire (message)
“all or nothing” principle
when nucleus decides to fire, it fires down the axon completely (all the way down) or not at all
intensity
strength or power of the message (only in one direction)
Depolarization
when message beings, sodium (+Na) ions come in and depolarize (neutralize) section of the axon - when opposites are no longer away (Na rushes in K rushes out)
Refractory period
Potassium (+K) ions are pushed out and neuron “pauses to reload” During this time a neuron is unable to fire - period of time after firing that the neuron is focused on resetting
reuptake
reabsorption of neurotransmitters by firing neurons
neurotransmitters
chemical substance that crosses the synapse to carry on the message to the next neuronsy
synapse
open space between two neurons at which neurotransmitters cross
receptor sites
specific points on dendrites of neurons that receive specific types of neurotransmitters
Neurotransmitter: Acetylcholine
muscle contracting, memory and learning (alzheimer’s)
Neurotransmitter: Glutamate
memory, major excitatory involved in memory, oversupply can lead to migraines and seizures
Neurotransmitter: dopamine
movement thought process, rewarding sensation (parkinson’s, schizophrenia, drug addiction)
Neurotransmitter: serotonin
emotional states, sleep (depression)
Neurotransmitter: norepinephrine
physical arousal. learning and memory (depression, stress)
Neurotransmitter: GABA
inhibition of brain activity (anxiety disorders)
Neurotransmitter: endorphins
pain perception, positive emotions, “runner’s high” (opiate addiction)
Neurotransmitter: substance P
pain +immunity, in the brain + spinal cord - associated with inflammatory processes and pain. oversupply can result in chronic pain
agonist
mimic neurotransmitter activity - fitting in receptor site like a master key, works just like the original key but exactly the same (morphine), stimulate and impersonate - indistinguishable from natural endorphins
antagonist
block neurotransmitters activity - fitting in the receptor like a fake key - preventing the neurotransmitter from getting to its receptor site and doing its job (Botox)
reuptake inhibitor
a type of antagonist that blocks the reuptake process to increase a neurotransmitter
nervous system
consists of all nerve cells - body’s speedy, electrochemical communication system
peripheral nervous system
sensory and motor neurons that connect CNS to rest of body
central nervous system
contains spine and brain, center of body
autonomic (peripheral)
controls involuntary functions/items that happen automatically within body (breathing, heartbeat, digesting)
somatic (peripheral)
controls voluntary movements and communications to and from the sense organs (you can control these, they don’t just happen)
brain (CNS)
neural center of body - control center
spinal cord (CNS)
super highway of nerves - body’'s means of transmitting messages to and from brain
sympathetic (autonomic)
physically arouses body, preparing it for action react in stressful situations, expending energy (initiates fight or flight)
parasympathetic (autonomic)
calms body, conserve energy and help keep a constant internal state (initiates rest and digest)
interneurons
only neurons in CNS, acting as messengers between sensory and motor neurons
sensory (afferent) neurons
carries incoming messages from sense receptors to CNS
motor (efferent) neurons
carries outgoing information from CNS to peripheral and muscles
endocrine system
communicates with the brain using chemical messages, called hormones
hormones
released into and circulate through the bloodstream (received only at a specific site) - works with parasympathetic system until normal circumstances to maintain homeostasis but when in crisis it works to support the sympathetic nervous system
pituitary gland
“master gland” directed by the hypothalumus
Hormone: adrenaline
adrenal glands, fight or flight, plays role in emotional memory formation same chemical as epinephrineHormone:
Hormone: leptin
turning off hungerHormone:
Hormone: ghrelin
turning on hunger
Hormone: melatonin
signals relaxation and lower body temp that helps with restful sleep
Hormone: oxytocin
us vs. them (social trust bonding)
cerebral cortex
outermost layer of cerebrum and most prominent part of brain - made up of grey matter that covers inner white matter of cerebrum - responsible for most of the sophisticated processing of the brain - higher order thoughts
corpus callosum
bundle of fibers that connects two hemispheres
hippocampus (limpic system)
converts short term memory into long term memory - involved in processing and retrieving declarative (facts and events) memory - spatial relationship memories - dysfunction: alzheimers and retrograde amnesia
thalamus (limbic system)
sensory switchboard - receives and sports sensory info, then sends it to the cortex for further interpretation - smell is the only sensory exception - relay center for senses but smell
hypothalamus (limbic system) F’s
fight or flight, feeding, fornication, homeostasis and hormones, reward/pleasure
amygdala (limbic system) A’s
anger, aggression, afraid (fear responses), also helps ingrain highly emotional memories - emotions
cerebellum (hindbrain)
balance and equilibrium - coordinated sequences of movement - implicit memory and nonverbal learning
pons (hindbrain)
bridge that connects brain stem and cerebellum - help coordinate and integrate movements on each side body - plays a role in sleep functions
medulla (hindbrain)
basic autonomic functions: heart rate, breathing, blood pressure - reflexes: swallowing , sneezing, vomiting
reticular formation (RAS)
a network of nerve fibers involved in attention, arousal, and alertness
hindbrain
lizard brain - brainstem, cerebellum, and hypothalamusm
midbrain
mammal brain- limbic system and hippocampus
forebrain
human brain - cerebral cortex
brain lesions
experimentally destroys brain tissue to study behaviors after such destruction - usually done for scientific or medicinal purposes (function)
EEG
an amplified recording of the electrical waves sweeping across the brain’s surface, measured by electrodes placed on scalp (function)P
PET Scan
positron emission tomography - a process that’s used to observe metabolic processes in the body and brain. Patient ingests a radioactive form of glucose, PET then takes a picture of it being used in the body/brain (function)
MRI
uses magnetic fields and radio waves to produce computer generated images that distinguish among different types of brain tissue (structure)
fMRI
measures brain activity by detecting changes associated with blood flow - the patient interacts with information during the scan to show activity (function)
CT/CAT Scan
computerized tomography - combines a series of x-ray images to allow taken from different angles, that create cross-sectional images of the body(bone) and brain (structure)
frontal lobe
prefrontal cortex - develops last - controls functions like: judgement, planning, producing speech sounds, controlling emotions, personality, temperament, movement (motor cortex) - works with motor cortex to make precise movements
parietal lobe
controls functions like: body positioning - spatial reasoning like: touch, pressure, temperature, pain - feeling
temporal lobe
on the side - controls functions like: hearing (primary auditory cortex), storing long term memories, speech and language - understanding
occipital lobe
controls functions like: all aspects of vision (primary visual cortex) - each piece of visual cortex corresponds to a particular place on the retina, receiving only info from that place, pieces are later put together to form the whole
association areas
over ½ of cerebral cortex is uncommitted to sensory or muscular activity - these areas are involved in higher mental functioning
wernicke’s area
area in left temporal lobe that is involved in language comprehension and expression
wernicke’s aphasia
doesn’t understand ahwat words mean
broca’s area
area in left frontal lobe that directs muscle movements involved in directing motor movement involved in speech
broca’s aphasia
unable to speak
left brain
language - controls right - speech, grammar, rules, reading, writing, math - verbal memory - language sounds - words, letters
right brain
rhythm - controls left - geometry, sense of direction, distance, mental rotation of shapes - emotional tone of speech - nonverbal memory - non-language sounds, music - geometric patterns, faces, emotional expression - “big picture”
corpus callosum
two hemispheres communicate/share information through…
brain neuroplasticity
brain’s ability to continuously change throughout ones life due to its use (if you don’t use it you lose it). Brain activity associated with a certain function can be transferred to a different location, particularly if the OG area is damaged
synaptic pruning
process by which extra neurons and synaptic connections are eliminated in order to increase the efficiency of neuronal transmissions (lose it)
long-term potentiation (LTP)
persistent strengthening of synapses based on recent patterns of synaptic activity that produce a long lasting increase in signal transmissions between two neurons (use it)
psychoactive drugs
a chemical substance that alters perceptions and mood (effects conciousness)
tolerance
more use leads to bigger doses to get desired effect
dependence
absence of drug may lead to feelings of physical pains (intense cravings) and negative emotions (pyschological)
withdrawal
upon stop taking a drug (after addiction) users may experience undesirable effects of withdrawal
depressants “downers”
drugs that reduce neural activity and slow body functions
stimulants “uppers”
excite neural activity and speed up body functions
hallucinogens (pyschodelics)
drugs that distort perceptions and evoke sensory images in the absence of sensory input
circadian rhythm
occur on a 24 hour cycle and includes sleep and wakefulness - controlled by hypothalamus - natural CR is 25 hours
NREM 1
light sleep - just drifting to sleep, may experience fantastic images or auditory hallucinations - theta waves: slower than alpha, feelings of weightfulness
NREM 2
light sleep - more relaxed, clearly asleep - sleep spindles: short bursts of brain activity occur
NREM 3
deep sleep - transitional stage to deeper sleep, deepest sleep of all, hard to awake, only occurs during first few cycles of the night - brain activity significantly slowed - Delta: slower, deep sleep
REM - paradoxical sleep
sleep cycle starts moving back to stage 1 - exhibits rapid eye movement and vivid dreams - brain very active but body relaxed and paralyzed - although still asleep brain engages in amplitude, fast and regular beta waves - much like aware aroused state - waves become rapid
insomnia
difficulty falling asleep or staying asleep
narcolepsy
overpowering urge to fall asleep that may occur while talking