CPJE Secrets: Clinical & Law Practice Flashcards

Comprehensive practice vocabulary flashcards covering antibacterial agents, chronic disease management, and California pharmacy jurisprudence based on the Secrets CPJE 2026 lecture notes.

Bicillin LA

An IM-only penicillin G benzathine formulation that must never be administered IV, intravascularly, or intra-arterially.

Augmentin

A combination of amoxicillin/clavulanate; the IR formulation is typically dosed $500\,mg$ q8-12h or $875\,mg$ q12h and the suspension should be refrigerated.

Vancomycin (Vancocin)

A glycopeptide antibiotic with a narrow therapeutic window; peak levels should be $\le 40\,mcg/mL$ and trough levels should be $< 10\,mcg/mL$ ($20\,mcg/mL$ for severe infections).

Red man syndrome

A complex associated with vancomycin infusion rates exceeding $15\,mg/min$, resulting in flushing and rash.

Isoniazid (INH)

A first-line antituberculous agent with a BBW for fatal hepatitis; neurotoxicity is prevented by co-administering Vitamin B6 (pyridoxine).

Amphotericin B

An antifungal used for life-threatening infections; it is nephrotoxic, causes electrolyte imbalances ($\downarrow K^{+}$, $\downarrow Mg^{2+}$), and is compatible with $D5W$ only.

PrEP (HIV Pre-Exposure Prophylaxis)

A prevention method for HIV-negative people at risk, requiring one tablet of tenofovir/emtricitabine ($Truvada$ or $Descovy$) daily; it reduces transmission risk by $99\%$ with $100\%$ adherence.

ACE Inhibitors (-pril)

Agents like lisinopril and enalapril used for hypertension and CKD; they carry a BBW for pregnancy and can cause a dry cough or angioedema.

Entresto

A combination of sacubitril and valsartan; it is the first-line therapy to reduce morbidity and mortality in Heart Failure with Reduced Ejection Fraction ($LVEF \le 40\%$).

High-intensity Statins

Lipid-lowering agents that lower $LDL-C$ by $\ge 50\%$, specifically atorvastatin ($40–80\,mg$) and rosuvastatin ($20–40\,mg$).

Metformin

The first-line drug for Type 2 Diabetes; it is contraindicated in patients with an $eGFR < 30\,mL/min$ due to the risk of Lactic Acidosis.

Lithium (Eskalith, Lithobid)

A mood stabilizer for bipolar disorder with a therapeutic range of $0.6–1.2\,mEq/L$; levels are increased by NSAIDs, diuretics, and ACEIs/ARBs.

Amiodarone (Cordarone)

A Class III antiarrhythmic with a half-life of $55$ days; it requires monitoring of the thyroid, liver, and lungs.

Digoxin (Lanoxin)

A positive inotrope and negative chronotrope; the therapeutic range for Heart Failure is $0.5–0.9\,ng/mL$ and toxicity is increased by hypokalemia ($K < 3.5\,mEq/L$).

MME (Morphine Milligram Equivalents)

A metric used to calculate the total daily dosage of opioids to gauge overdose potential; clinicians should avoid $\ge 90\,MME/Day$ unless justified.

Naloxone (Narcan)

A non-controlled opioid antagonist used as a rescue agent for respiratory depression in opioid overdose.

Pharmacist Continuing Education (CA)

A requirement of $30$ hours every $2$ years, including $2$ hours of Law and Ethics and $1$ hour of cultural competency.

Pharmacist-in-Charge (PIC)

A pharmacist who operates a maximum of $2$ pharmacies located within $50$ miles of each other and is responsible for complying with federal and state law.

DEA Form 222

The specific form required for the ordering of Schedule I and II controlled substances.

CURES

California's database for tracking Schedule II, III, IV, and V controlled substance prescriptions to reduce drug abuse and diversion.

iPLEDGE

A mandatory REMS program for isotretinoin requiring registration of patients, prescribers, and pharmacies to prevent fetal exposure.

USP

Compounded Sterile Preparations (CSPs) made in a Segregated Compounding Area (SCA) with a maximum BUD of $12$ hours at CRT or $24$ hours refrigerated.

USP

CSPs compounded in a cleanroom suite; the maximum refrigerated BUD for preparations with only sterile components is $10$ days.

Combat Methamphetamine Epidemic Act (CMEA)

Federal law limiting OTC sales of pseudoephedrine to $3.6\,grams/day$ and $9\,grams/30\,days$ ($7.5\,grams$ for mail order).

Emergency Refills (CA)

RPh can dispense a full refill for non-scheduled drugs or a reasonable quantity (e.g., $72\,hrs$) for Schedules III-V if the prescriber cannot be reached.

Schedule II Partial Fills

Allowed if the pharmacy is short on stock (balance must be filled within $72\,hours$) or if the patient is terminally ill (must be completed within $60\,days$).

Patient Consultation (CA)

Mandatory for all new prescriptions or modifications to existing ones; it must be oral and include directions for use, storage, and side effects.

Notice to Consumers Poster

A required posting in every California pharmacy that informs consumers about their rights to consultation and drug price publicity.