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chapter 1-4
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cell theory
smallest structural and functional living unit
organism functions depend on individual and collective cell functions
cells arise from preexisitng cells
biochemical activities of cells are dictated by their sub-cellular structures
cytology
scientific study of cells
squamous
thin, flat, scaly shape, bulge where nucleus is “sunny side up”
line the esophagus n air sacs (alveoli) of the lungs, form surface epidermis of skin
cuboidal
squarish looking in frontal sections equal in height and width, liver cells
columnar
taller than wide, inner lining cells of stomach n intestines
epithelial cells
squamous, cuboidal, and columnar
polygonal
irregularly angular shapes, 4-5 or greater sides (honeycomb), glands
stellate
multiple pointed projecting from body of a cell, giving it starlike shape, nerve cells
spheroidal to ovoid
round to oval, egg cells n White blood cell (white blood cells)
discoidal
disc-shaped Red blood cells(RBC)
fusiform
spindle-shaped ; elongated ; with thick middle n tapered ends (smooth muscle)
fibrous
long, slender, threadlike, as in skeletal muscle cells and axons of nerve cells
Anatomy
study of structural makeup of an organism or any of its parts
physiology
study of function of life or matter
How do Anatomy and physiology relate ?
They are interdependent one depends on another for example born without a right hand cant shake hands
structural complexity
atoms - molecules - organelles - cells - tissues - organs - organ systems - organism
Medial
towards the median or midline
lateral
away from the median or midline
proximal
closer to trunk or point of orgin
distal
further from trunk or point of orgin
anterior
front side or ventral side
posterior
back side or dorsal side
superior
above or towards the top (cranial)
inferior
towards the bottom or tail (caudal)
superficial (external)
closer towards the surface of skin
deep (internal)
further from the surface of the skin
Anatomical position
feet slightly apart standing erect palms facing out with thumbs pointed out
sagittal plane
creates left and right proportions
midsagittal plane
creates equal left and right proportions
transverse (horizontal plane)
creates top and bottom or superior and inferior proportions
frontal (coronal)
creates front and back / anterior posterior planes
Homeostasis
internal eequilibrium regardless of what happening in our outside environment keeping varibles in range
organism
exhibits : boundaries, responsivness, growth n development, movement, reproduction, digestion n metabolism, excretion
survival needs
nurtrients, oxygen, water, atomosphere pressure, normal body temp
needs to be in appropiate amounts too much or too little can be fatal
negative feedback
opposite response occurs/puts stimulus back in range
example of negative feedback loop sugar levels get to high we send insulin to bring it down
negative feedback loops
stimulus sends it to Receptor(sensors) then send it to the integrating center or control center then it will send it to effectors which give a response
Energy flow in human physiology
most of these flow down the grandient (passively) we only have a select few of things that goes against the gradient (actively)
Positive feedback loop
increase in variability away from the setpoint / enhance initial response (pregnancy and blood clotting)
Bio chemistry
study of molecules that compose living organisms
element
simplest form of matter to have unique chemical properties
body mass is composed of what
96% composed of O,C,H,N
atoms
make up an element gives it particular physical and chemical properties
protons
carry a positive charge
neutron
carry a neutral charge
electron
carry a negative charge and orbits the nucleus
what two atoms make up the nucleus ?
protons and neutrons = atomic mass
isotopes
structural variations of elements that differ in number of neutrons they contain
radioisotopes
unstable isotopes that give off energy (radioactivity)
molecule
two or more atoms coming together (O2,H2)
compound
two or more different atoms bonded together (NO, H2O)
chemical bonds
energy relationships between electrons of reacting atoms
Shell 1
can only hold 2 electrons
shell 2
maximum of 8 electrons
shell 3
maximum of 18 electrons
Octet rule
besides the first shell all other shells want to reach 8 electrons in outermost shell in order to be “happy”
chemically inert gases
stable and unreactive because they follow the octect rule
“noble gases”
chemically reactive elements
outermost level not fully occupied by electrons
ions
atoms that have gained or lost electrons and become charged
anions
gain an electron and become more negative charged
cations
lose an electron and become more positive
what results in an ionic bond
attraction of opposite charges
covalent bonds
formed by sharing of two or more valence shell electrons
nonpolar covalent bonds
equal sharing produces electrically balanced nonpolar molecules (CO2)
polar covalent bonds
unequal sharing by atoms with different electron-attracting abilities produces polar molecules
hydrogen bond
attractive force between electropositive hydrogen and electronegative atom of another molecule
Van der Waals force
weak attraction between two atoms occurring when a brief fluctuation in the electron cloud density of 1 atom induces polarization of an adjacent form
Water
60-80% of volume of living cells
high heat capacity
absorb and relase heat with little temp change
prevents sudden changes in temp
high heat vaporization
requires large amount of heat to evaporate useful cooling mechanism
polar solvent properties
forms hydration layers charged molecules
bodys major transport
reactivity
necessary part of hydrolysis n dehydration reaction synthesis
cushioning
protects certain organs from physical trauma
solvent
present in greatest amount, usually liquid dilutes the solute
solute
present in smaller amounts typically something like salt dissolved in another substance
Solution
a solute salt is dissolved in another substance water known as a solvent which creates this (body fluid - urine, intersitial fluid, blood plasma)
suspension
flour suspended in water (appears light blue because blue light is scattered off the flour particles to a greater extent than red light) (body fluids - whole blood,chyme)
colloid
milk is an emulsified colloid of liquid butter globules dispersed within a water based liquid. Stabilized in suspension by electrostatics-mutual repulsion of like electrical charges (body fluids - mucous,lymph,whole blood plasma,cytoplasm)
acids
protons donors (H+) release Hydrogen ion in solution
increase in Hydrogen means decrease in ph
ph levels 0-6.99
bases
protons acceptors take up H+ in the solution
OH- increase hydrogen decreases causing PH to increase
ph 7.01-14
neutral solutions
equal amount of OH and H ions
ph 7
blood ph range
7.35-7.45
ph is regulated by kindeys, lungs, and what type of buffers
buffers - mixtures of compounds that resist ph changes
bicarbonate ion [HCO3] bind to hydrogen when we are too acidic
ammonia [NH3] binds to hydroxyl groups when we are too basic
matter
anything that has mass or occupies space
mass
the amount of matter in a object, its resistance to being acclerated
mixtures
combination of two or more substances that are physically combined
energy
capacity to do work
work
move something
kinetic energy
energy of motion, doing work
potential energy
stored energy or contained in a object because of position or internal state not doing work
First law of thermodynamics
energy is transferred from one form into another
chemical energy
fuel oil burners
stored in bonds of chemical substances
electrical energy
power lines
results from movementss of charged particles
mechanical energy
dams
moving matter/muscles moving bones
radiant or electromagnetic energy
sunlight, uv rays, x rays, heat, travels in waves
chemical equilibrium
neither a foward nor reversible reaction occurs
why are many biolofical reactions essentially irreversible?
energy requirments and removal of products
synthesis reactions
also anabolic reactions where your reactants form a bond
endergonic - when formed products contain higher potential energy
A + B - AB
endothermic
takes in heat
exothermic
releases energy/heat
decomposition
reverse synthesis and also catabolic reaction
involves breaking of bonds
exergonic reaction - releases energy
AB - A + B
exchange reactions = displacement reactions
AB + C - AC + B
bonds are both broken and made
rate of chemical reactions
temperature increase rate increases
particle size decreases rate increases
concentration of reactant increases rate increases
catalysts
increase rate without being chemically changed
example enzymes which are very specific work with certain substrates
oxidation
electrons donors lose electrons and become oxidized
reduction
electron acceptors receive electrons and become reduced