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Microbiology
The study of microorganisms, including bacteria, viruses, fungi, and parasites, and their effects on humans.
Pathophysiology
The study of the functional changes that occur in the body as a result of a disease or medical condition.
Antimicrobial resistance
The ability of microorganisms to withstand the effects of medications that once killed them or inhibited their growth.
Healthcare-acquired infections
Infections that patients acquire while receiving treatment for medical or surgical conditions.
Fungal infections
Infections caused by fungi, which can be more complex due to their unique characteristics compared to bacteria.
Gram stain
A laboratory technique used to differentiate bacterial species into two groups based on the characteristics of their cell walls.
Gram-positive
Bacteria that retain the crystal violet stain used in the Gram staining procedure, appearing purple under a microscope.
Gram-negative
Bacteria that do not retain the crystal violet stain used in the Gram staining procedure, appearing pink under a microscope.
Human microbiome
The collection of microorganisms living in and on the human body, playing a crucial role in health and disease.
Infectious disease
Diseases caused by pathogenic microorganisms, such as bacteria, viruses, parasites, or fungi.
Epidemiology
The study of determinants, occurrence, and distribution of health and disease in a defined population.
Health technology assessment
The systematic evaluation of the properties and effects of health technology, including its direct and intended effects.
Surveillance and control
The ongoing systematic collection, analysis, and interpretation of health data for planning, implementation, and evaluation of public health practice.
Risk, screening, and prevention
Strategies aimed at reducing the likelihood of disease occurrence through early detection and intervention.
Infection
The replication of organisms in host tissue, which may cause disease.
Carrier
An individual with no overt disease who harbors infectious organisms.
Dissemination
The spread of the organism in the environment.
Epidemiologic triad
A model that describes the interaction of host, agent, and environment in the spread of infection.
Equilibrium state
A condition where the interactions among host, agent, and environment are balanced, indicating health.
Teeter totter model
A visual representation of the balance between host, agent, and environment in relation to health and disease.
Patient management
The process of planning and providing care to patients based on their individual health needs.
Infection control
Procedures and practices aimed at preventing the spread of infections in healthcare settings.
Disease transmission
The process by which an infectious agent is spread from a reservoir to a susceptible host.
Epidemiologist
Deciphers connection between the agent, host, and environment in disease transmission.
Imbalance towards the Agent
The agent having more ability to cause a disease in humans, exemplified by the 2021 coronavirus.
Imbalance towards the Host
The increased susceptibility of individuals to diseases, illustrated by the H1N1 flu virus.
Chain of Infection
A series of events that enable microorganisms to cause infections in a person.
Types of Carriers
Different classifications of individuals who can transmit diseases.
Convalescent Carrier
Individuals who have recovered from illness but can still transmit the disease.
Healthy Carrier
Sub-clinical cases that remain well during the infection stage and never develop symptoms.
Active Carrier
An infected individual who can transmit the disease.
Incubating Carrier
Individuals who can transmit the agent during the incubation period before clinical illness begins.
Communicable Diseases
Diseases transmitted from one person or animal to another, directly or indirectly.
Sporadic Diseases
Diseases that occur infrequently and irregularly within a population in a specific geographic area.
Epidemic Diseases
A sudden increase in the number of cases of a disease in a specific region over a short period.
Endemic Diseases
Diseases consistently present in a population or geographic area, with fluctuating cases over time.
H1N1 Flu Virus
An RNA virus that mutates frequently, requiring annual changes to the flu vaccine.
Transmission
Occurs when an agent leaves its reservoir or host through a portal of exit and enters a susceptible host.
Direct Contact
A mode of transmission where diseases are spread through physical interaction.
Vectors
Organisms, like mosquitoes, that transmit diseases such as malaria.
Contaminated Surfaces
Surfaces that can harbor pathogens and facilitate disease transmission.
Preventive Measures
Specific actions like isolation, masks, and hygiene practices required to control disease spread.
Environmental Factors
Conditions that can influence the emergence of epidemic diseases.
Immunization
A public health strategy to control sporadic diseases.
Public Health Programs
Initiatives that can prevent the reemergence of sporadic diseases.
Incidence
Depends on factors like environment, population immunity, and pathogen virulence.
Pandemic Diseases
Occurring in epidemic proportions across multiple countries, often worldwide.
HIV/AIDS, TB, Malaria
Collectively cause more than 300M illnesses and more than 5M deaths per year.
Common Modes of HIV Transmission
1. Sexual contact 2. Transfusion 3. Contaminated needles 4. Perinatal transmission.
Primary Prevention
Measures aimed at a susceptible population to prevent a disease from ever occurring.
Secondary Prevention
Emphasizes early disease detection in healthy-appearing individuals with subclinical forms of the disease.
Tertiary Prevention
Targets both clinical and outcome stages of a disease to reduce severity and associated sequelae.
Primordial Prevention
Risk factor reduction targeting the entire population, focusing on social and environmental conditions.
Quaternary Prevention
Action taken to protect individuals from medical interventions that are likely to cause more harm than good.
Example of Primary Prevention
Common activities include limiting risk exposure or increasing immunity of individuals at risk.
Example of Secondary Prevention
Papanicolaou (Pap) smear aimed to diagnose cervical cancer in its subclinical state.
Example of Tertiary Prevention
Rehabilitation efforts implemented in symptomatic patients to mitigate disease severity.
Example of Primordial Prevention
Improving access to safe sidewalks in urban neighborhoods to promote physical activity.
Example of Quaternary Prevention
Identifying patients at risk of overmedicalization and suggesting ethically acceptable interventions.
Mortality from 1918 Spanish flu pandemic
Over 20 million people were killed.
Target population for Primary Prevention
Healthy individuals.
Target population for Secondary Prevention
Healthy-appearing individuals with subclinical forms of the disease.
Target population for Tertiary Prevention
Symptomatic patients.
Target population for Primordial Prevention
Entire population.
Target population for Quaternary Prevention
Patients with illness but without the disease.
Role of Nursing and Allied Health
Proper communication to provide appropriate levels of prevention to the general public and patients.
Importance of Education for School Staff
Educating staff on the importance of providing prevention as an aspect of caring for students.