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Integumentary Functions
Protection, synthesis, sensation, thermoregulation, social
Keratinized cells
make skin resistant to injuries, protection barrierSkin
Epidermis Layers from superficial to deep
Corneum, lucidum, granulosum, spinosum, basale
Stratum corneum
dead, keratinized cells
Stratum lucidum
Filled with precursor to keratin
Stratum granulosum
granules of waterproofing substance, materials to make keratin. Cells undergo apoptosis.
Stratum spinosum
Desmosomes hold cells together
Stratum basale
Stem cells that produce keratinocytes, Merkle cells, melanocytes. Attached to basement membrane
Dermis Layers superficial to deep
Papillary, reticular
Is a layer of areolar connective tissue. Contains thin collagen fibers, leukocytes, capillaries, dermal papillae.
Papillary
Made of dense irregular connective tissue and pocket of adipose tissue.
Reticular
surface sensory receptors
Meissner’s corpuscle
Deep sensory receptors
Pacinian corpuscle
Shots are injected into
Hypodermis
Cell shapes of the epithelial
columnar or cuboidal in stratum basale, become more flattened moving towards surface.
How many layers of epithelium divide?
3-5
Hair follicle is attached to this that makes it stand upright
Arrector pili (smooth) muscle
Glands in hair follicle
Apocrine and sebaceous
Types of cutaneous glands
Merocrine, apocrine, sebaceous, ceruminous, mammary
Regular sweat glands all over, secretes water to cool body, opens to outside
Merocrine (Eccrine)
Cutaneous glands are found in what layer?
Reticular
Public hair, flow into hair follicles, produce pheromones, coiled gland
Apocrine
Produce sebum, flask shaped, open to hair follicle, prevents skin drying out, holocrine
Sebaceous
Opens directly to surface, found in outer ear canal, secretes Cerumen
Ceruminous
Cancer Types:
Malignant melanoma, Basal cell carcinoma, squamous cell carcinoma.
ABCDEs of Nevi
Asymmetry, Border irregularity, color, diameter, evolution
Types of wound repair
Regeneration, fibrosis repair
Involves replacement of damaged cells with same type of cells
Regeneration
Forms clot/scab, replaces damaged tissue with scar tissue
Fibrosis/repair
After a cut, blood vessels release
leukocytes, antibodies, clotting factors, protein (fibrin)
Repair sequence
Blood vessels grow and repair, macrophages enter and remove damage and clot blood, fibroblasts synthesize new collagen to repair connective tissue, new collagen laid down by fibroblasts.
Epithelial cells proliferate and hep repair
Remodeling
Garbrect’s kids name
Zander
Endocrine glands release secretions into
the bloodstream
What is the mode of secretion of sebaceous glands?
Holocrine
Fingerprints are called
friction ridges
Which of the following is an epidermal cell with an immunological function?
dendritic cell