citric acid cycle

Step 1 enzyme

Citrate Synthase

Step 2 enzyme

Aconitase

Step 4 enzyme

a-keotregulate dehydrogenase complex

Step 3 enzyme

Isocitrate dehydrogenase

Step 5 enzyme

Succinyl CoA-synthetase

Step 6 enzyme

Succionaste Dehydrogenase

Step 7 enzyme

Fumarase

Step 8 enzyme

Malate Dehydrogenase

Regulatory Enzmyes

Citrate Synthase, Isocitrate dehydrogenase, & a-ketoreglutarate dehydrogenase

What does CAC yield

3 NADH, 1 FADH2, and GTP

Step 1 product

Citrate

Step 2 product

Isocitrate

Step 3 product

a-ketoregulate

Step 4 product

Succinyl-CoA

Step 5 product

Succinate

Step 6 product

Fumarate

Step 7 product

Malate

Step 8 product

Oxaloacetate

Negatory Effects of Citrate synthase

ATP, NADH, and succinyl-CoA

Positive effectors of citrate synthase

ADP

Negative effectors of Isocitrate dehydrogenase

ATP and NADH

Positive effectors of Isocitrate dehydrogenase

ADP

Positive effectors of Isocitrate dehydrogenase

ADP

Negative effectors of a-ketoregulate dehydrogenase

Non

Where does the CAC occur in eukaryotes

Mitochondrial matrix

Where does CAC occur in prokaryotes

The cytoplasm

What is the rate limiting enzyme

Isocitrate dehydrogenase

The reaction catalyzed by fumarase requires

H20

The reaction catalyzed by an a-ketoregulate dehydrogenase also synthesizes

NADH and CO2

The reaction catalyzed by citrate synthase also synthesizes

CoA

The reaction catalyzed by succinyl CoA synthetase also synthesizes

GTP and CoA

The reaction catalyzed by Malate dehydrogenase also synthesizes

NADH and H+

The reaction catalyzed by succinate dehydrogenase also synthesizes

FADH2