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Arterial Insufficiency
Deficiency or occlusion of blood flow through an artery
Chronic inflammation
Low-grade, protracted inflammatory process
Collagen
Supportive, strong, and fibrous connective tissue protein that is found in the dermis, tendon, cartilage, fascia, ligament, and bone
Dermatitis
Inflammation of the skin indicated by any one or all of the following: redness, rash, itching, irritation, and possible skin lesions
Epidermis
Outermost layer of skin
Ground substance
Supportive amorphous, gel-like substance secreted by fibroblasts; fills space between connective tissue fibers and cells
Hypertrophic scar
Excess of collagen deposited at the site of a healing or healed wound that is noticeably different from the normal skin; scar remains within the boundaries of the original wound
Inflammatory phase
Phase of wound healing encompassing vascular reactions that decrease blood loss and initiate vessel repair, and cellular responses that moderate blood loss, fight infection, and provide nutrition and oxygen to initiate and sustain tissue repair
Inflammatory skin diseases
Diseases of the skin whose etiologies invoke an inflammatory response (etiologies for these diseases commonly include immune reactions and contract irritants or allergens)
Integument
Skin
Keloid scar
Excess of collagen deposited at the site of a healing or healed wound that is noticeably different from normal skin: scar commonly extends beyond the boundaries of the original wound
Maturation phase
Phase of wound healing that includes collagen synthesis and lysis, as well as reorientation of the collagen fibers that remain at the wound site; this phase may also be referred to as the remodeling phase.
Neoplastic skin diseases
Cancers affecting the skin
Neuropathic (neurotropic) ulcer
Skin lesion caused by a decreased cutaneous sensation that disallows protective responses such as weight transfer; these ulcers are commonly associated with diabetes mellitus
Pressure ulcer
skin lesion caused by ischemia of the integument secondary to pressure; generally located at bony prominences
Proliferative phase
phase of wound healing that involves increased activity of fibroblasts, instigation of aggressive wound contraction, and epithelialization
Scar contraction
Dynamic movement of the edges of a scar (wound boundaries) toward each other
Scar contracture
Permanent or relatively permanent lack of mobility of the scar tissue that results in functional and/or cosmetic impairment
Total body surface area (TBSA)
Represents the extent of the surface of the body covered by skin. Th e percent TBSA used to describe the size of a skin injury (routinely used to estimate the size of a burn injury)
Vancouver Burn Scar Scale
Clinical method for assessing scar tissue. The characteristics of scar that are examined include pigmentation, vascularity, pliability, and height.
Venous insufficiency
Deficiency or occlusion of blood flow through a vein