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Muscular system
Consists only of skeletal muscles
Myology
The study of muscles
Functions of muscle tissue
Movement of body parts and contents, communication, stability, posture, control of body openings, heat production, and glycemic control
Excitability
The ability of muscle cells to respond to chemical signals, stretch, and electrical changes
Conductivity
The ability to propagate electrical signals along the muscle cell membrane
Contractility
The ability of muscle cells to shorten forcefully when stimulated
Extensibility
The ability of muscle cells to stretch without damage
Elasticity
The ability of muscle cells to return to original length after contraction
Skeletal muscle
Voluntary, striated muscle usually attached to bones
Cardiac muscle
Involuntary, striated muscle found only in the heart
Smooth muscle
Involuntary, nonstriated muscle found in viscera
Muscle fiber
A muscle cell
Sarcolemma
Plasma membrane of a muscle fiber
Sarcoplasm
Cytoplasm of a muscle fiber
Myofibrils
Cylindrical bundles of myofilaments that fill the sarcoplasm
Sarcoplasmic reticulum
Specialized smooth ER that stores calcium ions
Transverse (T) tubules
Invaginations of the sarcolemma that conduct action potentials into the fiber
Myoglobin
Oxygen-binding protein that gives muscle its red color
Myofilaments
Protein filaments responsible for muscle contraction
Thick filaments
Composed primarily of myosin
Thin filaments
Composed primarily of actin, troponin, and tropomyosin
Myosin
Motor protein with projecting heads that bind actin
Actin
Protein forming the backbone of thin filaments
Tropomyosin
Protein that blocks myosin-binding sites on actin
Troponin
Protein that binds calcium and shifts tropomyosin
Titin
Elastic protein that anchors thick filaments to Z discs
Striations
Alternating dark and light bands seen in skeletal and cardiac muscle
A band
Dark band representing the full length of thick filaments
I band
Light band containing thin filaments only
Z disc
Boundary between adjacent sarcomeres
Sarcomere
Smallest functional contractile unit of muscle
Neuromuscular junction
Synapse between a motor neuron and a muscle fiber
Acetylcholine (ACh)
Neurotransmitter released by motor neurons
Motor unit
One motor neuron and all the muscle fibers it innervates
Excitation-contraction coupling
Sequence linking muscle excitation to contraction
Power stroke
Pivoting of myosin heads that pulls thin filaments
Relaxation
Process in which calcium is pumped back into the sarcoplasmic reticulum
Slow oxidative fibers
Type I fibers that are fatigue resistant and use aerobic respiration
Fast glycolytic fibers
Type II fibers that fatigue quickly and rely on anaerobic metabolism
Muscle hypertrophy
Increase in muscle fiber size due to increased myofilaments
Muscle atrophy
Decrease in muscle size due to disuse or denervation
Neurobiology
The study of the nervous system
Nervous system
System specialized for sensory perception, integration, and motor control
Central nervous system (CNS)
Brain and spinal cord
Peripheral nervous system (PNS)
Nerves and ganglia outside the CNS
Neuron
Nerve cell specialized for rapid electrical communication
Excitability
Ability of neurons to respond to stimuli
Conductivity
Ability of neurons to transmit electrical signals
Secretion
Ability of neurons to release neurotransmitters
Sensory (afferent) neurons
Detect stimuli and transmit information to the CNS
Interneurons
Receive signals from other neurons and process information
Motor (efferent) neurons
Transmit signals from the CNS to muscles and glands
Neurosoma (cell body)
Control center of the neuron
Chromatophilic substance (Nissl bodies)
Rough ER of neurons
Dendrites
Receive incoming signals from other neurons
Axon
Conducts action potentials away from the neurosoma
Terminal arborization
Branched distal end of an axon
Axon terminals
Release neurotransmitters to target cells
Multipolar neuron
One axon and many dendrites
Bipolar neuron
One axon and one dendrite
Unipolar neuron
Single process extending from the cell body
Neuroglia
Supportive cells of nervous tissue
Oligodendrocytes
Form myelin sheaths around CNS axons
Schwann cells
Form myelin sheaths around PNS axons
Myelin sheath
Insulating layer that increases conduction speed
Nodes of Ranvier
Gaps between myelin segments
Saltatory conduction
Rapid conduction of action potentials from node to node
Astrocytes
Provide structural and metabolic support to neurons
Microglia
Phagocytic cells providing immune defense
Ependymal cells
Line ventricles and circulate cerebrospinal fluid
Satellite cells
Support neurons in peripheral ganglia
Synapse
Junction where a neuron communicates with another cell
Chemical synapse
Synapse using neurotransmitter release
Electrical synapse
Synapse using gap junctions for ion flow
Neurotransmitter
Chemical messenger released at synapses
Excitatory synapse
Increases likelihood of postsynaptic action potential
Inhibitory synapse
Decreases likelihood of postsynaptic action potential
Nerve regeneration
Regrowth of damaged PNS axons if the cell body remains intact
Neurulation
Formation of the neural tube during embryonic development