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Prevalence of mental illness in Weston nations across lifespan
1 in 5
what is NOT a symptom of schizophrenia
violence
difference between thoughts and auditory hallucinations
Whether words spoken are coming from inside your mind or outside your mind
Self talk v someone talking to you
what is catatonia
rigid in movement and immobility (uncommon)
annual societal cost of schizophrenia in england
11.8 billion pounds ($20 billion)
most common male onset of schizophrenia
~21 yrs old
most common female onset schizophrenia
27 years old
what is schizophrenia often referred to as
the prototypical psychotic disorder
features of schizophrenia
most common psychotic disorder, involves disturbances in all 5 symptom domains
delusions of persecution
paranoid flavour. Other ppl are out to get you
Treatment schizophrenia
-Medication: Frontline
-Psychological
Medication and schizophrenia, failure rate, side effects
-Frontline treatment
-Positive symptom profile: better response to antipsychotics
-25% fail to improve
-Side effects: weight gain, tardive dyskinesia (involuntary neurological movement disorder affecting lower face)
Psychological treatment for schizophrenia
-Psychoeducation patient and family
-Signs of relapse most important
-Behavioral strategies to develop social skills
-CBT for stable patients (but effect size likely to be in small range)
-Family support
How many people who experience mental illness receive any kind of intervention
50%
prevalence of schizophrenia
0.5-1%
Why is schizophrenia the highest impact disorder
Affects on individual
Affects on family
Economic cost associated with
age of onset of schizophrenia
Common 15-35
Uncommon >40, <10
Lifetime risk of suicide in schizophrenia
5%
Risk factors for suicide in schizophrenia
Male
Younger
Higher level education
Family history suicide
Comorbid substance use
Depressive symptoms
Previous suicide attempts
Why do schizophrenics die younger
Up to 40% premature mortality due to suicide and unnatural deaths
late-onset schizophrenia
the schizophrenia that first appears after age 40
potential social factor associated with the incidence of Schizophrenia
lower socioeconomic status
Difference between direct and indirect costs
Direct: resources that are used to treat or support an individual with an illness. e.g. hospital admissions, GP visits, employment support, accomodation
Indirect: value of the loss of productivity that schizophrenics and careers unable to contribute related to:
-illness or
-early mortality related to illness
Examples of indirect costs of schizophrenia
-Loss of earnings patient and career
-income tax
-Cost of support payments
-Costs associated with absenteeism
What's disability adjusted life years (DALYS)
-largest amount of economic burden.
-Sum of years of potential life lost due to premature mortality and the years of productive life lost due to disability.
Diagnostic systems
Diagnostic and Statistical Manual of Mental Disorders or the DSM
The International Classification of Diseases or the ICD.
What are the other criterions for schizophrenia
-Degree of dysfunction
-Duration
-Exclusion of other possible causes
Such as substance use or other mental illnesses
Diagnostic criteria for schizophrenia (DSM-V)
-Symptoms present 6 mos or longer
-At least 1 month of active symptoms
-At least 2+ symptoms below
-Delusions
-Hallucinations
-Disorganized speech
-Disorganized or catatonic behaviour
-Negative symptoms
What category and criterion do we examine for Schizophrenia as per DSM5
-Category: Schizophrenia Spectrum and Other Psychotic Disorders.
-Criterion A (Symptoms):
Positive and negative symptoms
Positive: happening too much (more than normal)
Negative: Occurring not enough (deficits)
Delusions
-Positive symptom
-Related to content of thought that is inaccurate or false and can’t be explained by religious/cultural beliefs
-False belief
-Two types (grandeur, persecutions)
Delusions of grandeur
ppl believe they possess qualities or attributes which make them better than other ppl. e.g. "I am a billionaire" "I am besties w Michael Jackson" "I am jesus" "I have found the cure to cancer"
Disorganized speech symptoms
-Positive symptom
-Related to disturbance is form of thought
(Speech best reflection of thoughts)
-When thoughts disorganized and disturbed so is speech
-Prolonged and extreme
Disorganized speech types
-Neologism
-Word salad
-Tangentiality
Neologism
Person makes up a word. No meaning in mainstream lang and is often a combo of 2 words or distortion of word. Usually is meaningless
Word salad
bunch of words tossed together which make no sense. Reflection of chaotic thought processes and meaningless
Tangentiality
Disturbance in associative thought patterns
Go from one topic to another unrelated topic
Tangentiality is normal, what differentiates it in schizophrenia
-Failure to return to original topic
-Lack insight
Hallucinations
-Disturbances of perception
-False sensory experience
- distressing for ppl experiencing them
Different types of Hallucinations
-Auditory
-Visual
-Olfactory
-Gustatory
-Tactile
most common features/type of hallucination
-Auditory is most common
-Hearing voices most common
-Mostly negative
What type of hallucination most common in organic brain disease
Visual
Olfactory hallucination definition
hallucination of smell
Gustatory hallucination definition
tasting somethig that ur not actually tasting. e.g. food you're eating tastes rotten even if to everyone else it tastes fine
Disorganized or catatonic motor behavior
-positive symptom
-Lack of focus or silliness
-Psychomotor agitation
-Purposeless activity
-Self initiated bizarre postures
Negative symptoms
-Affect
-Speech
-Emotion
-Alogia
-Avolition
-Lack self care hygiene
Alogia
-Poverty of speech
-Involves lack of spontaneous speech
-Impoverished thought processes
Avolition
Lack of motivation and social withdrawal. seen across lots of mental disorders
Course of schizophrenia
Episodic
Phases of psychotic episodes in schizophrenia
-Prodromal: General decline. negative symptoms start to appear. can last days/weeks/months
-Active: positive and negative symptoms. each symptom profile very different
-Residual: positive symptoms remitted, some negative remain. similar to prodromal
Which phase is diagnosed retrospectively in schizophrenia and when
Prodromal usually diagnosed once moved into active stage
Is short or long onset of prodrome associated with better or worse prognosis
Short/Acute: Better prognosis
Long/Chronic: Worse prognosis
Aetiology of schizophrenia
-Biological factors
-Social factors
-Psychosocial factors
-Gene by environment interaction best evidence (diathesis-stress model)
Biological factors in schizophrenia
-Genetics
-10% increased incidence with first degree relative
-50% increased incidence with identical twin
-Physical trauma: birth and pregnancy
-Structural brain abnormalities
-Biochemical abnormalities: Particularly dopamine
Social factors contributing to aetiology
-harmful stressors: stress, social isolation, poor nutrition, lack of access to medical services, Low social economic status
-Social dislocation (higher rates migrants)
Psychosocial factors
Expressed emotion: Level of:
-Criticism
-Hostility
-Emotional over involvement
High lvl of neg expressed emotion = higher risk of relapse
Diathesis-Stress model
interaction between genes and environment
-Underlying vulnerability
-(Diatheses) Genetic factors, physical trauma prenatally or during birth, structural abnormalities in brain or neurotransmitter system
-(stressors) chronic psychological and social stressors, family environment, drug use
Converts to illness if both present and interact