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abnormal narrowing of arteries other than those that supply the heart/brain
PAD
what is the leading cause of PAD?
atherosclerosis
what is the greatest risk factor for PAD?
cig smoking
with PAD, involvement of what vessels is common in elderly and diabetics?
distal/smaller
PAD classically occurs where?
at bifurcations
what are the 3 classic bifurcation locations for PAD?
aortoiliac
femoral-popliteal
infrapopliteal or tibial
what is the MC sx of PAD?
intermittent claudication
(cramping pain in legs w/ walking & relieved w/ rest)
in what condition may pt's dangle their legs over the side of the bed to relieve leg pain?
PAD
chronic ischemic pain at rest, ulcers, or gangrene (> 2wks)
critical limb ischemia -- EMERGENCY
PAD typically presents w/ decreased or absent pulses _____ to the obstruction
or with the presence of ____ over the narrowed artery
distal
bruits
what is the intial test of choice for PAD?
ankle brachial index
what ABI values is considered diagnostic for PAD
< 0.90
what ABI values indicate the pt needs to see a specialist?
> 1.4 or < 0.8
pts with ______ or _____ may have falsely elevated ABIs as a result of arterial claudification
diabetes or end-stage renal disease
what are the names of the 2 scales that assess PAD severity?
fontaine stages
rutherford
what are the 2 goals of PAD treatment?
lower CV risk
improve walking ability
arterial occlusion that results in the sudden cessation of blood flow to an extremity
acute limb ischemia
EMERGENCY
in acute limb ischemia (PAD), what is the MCC/source?
emboli
heart, aorta, large arteries
in acute limb ischemia (PAD), what can an emboli in the heart cause?
a-fib
what sx is diagnostic for acute limb ischemia (PAD)?
sudden pain in limb w/ decreased pulses
in acute limb ischemia (PAD), the extent of pain in limb w/ decreased pulses depends on what?
which artery is affected
what are the 6 P's for acute limb ischemia?
pain
pallor
pulseless
poikilothermia (cool)
paresthesia
parlysis
compression of neurovascular structures supplying the UE
associated w/ pain, numbness, weakness, and swelling
thoracic outlet syndrome
the following are causes of what?
- compression between scalene muscles and 1st thoracic rib
- sagging of shoulder girdle (aging, obesity, pendulous breasts)
- proximity of clavicle to 1st rib
- abnormal insertion of pec minor muscle
thoracic outlet syndrome
what is being compressed based on the following sx? (TOS)
- shoulder/arm pain, weakness, paresthesias
nerves
what is being compressed based on the following sx? (TOS)
- claudication
- raynauds phenomenon
- ischemic tissue loss/gangrene
artery
what is being compressed based on the following sx? (TOS)
- thrombosis of subclavian and axillary
- "paget-schoetter syndrome"
vein
the diagnosis for TOS consistis of the following regimen
- maneuvers to provoke ______
- maneuvers to cause a subclavian ______
- maneuvers to diminish _____
symptoms
artery bruit
arm pulses
what are the 5 maneuvers that used done for TOS?
adson
reverse adson
costoclavicular compression
wright
roos
causes pre/syncope related to cerebral hypoperfusion that occurs during arm use
subclavian steal syndrome
subclavian steal syndrome is most commonly due to blockage of what?
L subclavian
what is the dx study for subclavian steal syndrome?
if insufficient?
arterial US
CT angiography
what is always the 1st line tx for subclavian steal syndrome?
tx underlying cause
what is the MC reason for carotid artery bifurcation?
atherosclerotic occlusive plaque
in carotid artery disease, 85% of strokes are what kind?
ischemic
(bc of hypoperfusion from artery occlusion)
carotid bifurcation is an area of _____ flow velocity and _____ shear stress
low; low
transient monocular blindness (temporary loss in 1 eye) often described as a window shutter coming down or grey vision
what is this a common sx of?
amaurosis fugax
stroke in CAD
what is the tx for CAD if pt has 50-69% stenosis and is ASYMP? (2)
intensive medical therapy (ACE/ARB, anti-platelet, statin)
surveillance carotid US
what is the tx for CAD if pt has 70-99% stenosis and is ASYMP? (2)
intensive medical therapy (ACE/ARB, anti-platelet, statin)
carotid revascularization
T/F pts with CAD 50-69% stenosed and asymptomatic are NOT recommended to have revascularization
true - no revascularization
what is the tx for CAD in pts who are symptomatic and with 70-99% stenosis and a 2-year life expectancy?
carotid endarterectomy
what is the tx for CAD in pts who are symptomatic and with 50-69% stenosis and a 3-year life expectancy?
carotid endarterectomy
the following CAD pts are better candidates for _____ rather than open surgery
- unsuitable lesion for surgery
- radiation-induced stenosis
- conditions w/ increased risk of anesthesia
stenting
when treating CAD<, the periprocedural risk of stroke/death is higher with _____ than with _____
CAS (stenting)
CEA (endarterectomy)
pathologic dilation of a segment of a blood vessel =
aneurysm
normal abdominal aorta =
abdominal aortic aneurysm =
2cm
3cm
a true aneurysm involves what layers of the vessel wall?
all 3 (intima, media, adventitia)
what is it called when the intimal and medial layers of vessel wall are disrupted but not adventitia layer?
psuedoaneurysm
aneurysm that forms where your aorta carries blood into your abdomen
AAA
aneurysm that affect an artery in your brain =
what is the MC type?
cerebral
saccular (sac of blood [that looks like a berry] attaches to an artery)
aneurysm that forms in the upper part of your aorta (in your chest)
thoracic aortic aneurysm
aneurysm that forms in the artery that brings blood to your intestines
mesenteric artery aneurysm
traumatic aneurysms (after non/penetrating chest trauma) most commonly affect what?
descending thoracic aorta
all ____ aneurysms are at risk for expansion and rupture
most are fusiform (spindle shaped & entire circumference of aortic wall)
AAA
what is the risk of rupture for AAAs that are > 5cm?
20-40%
what is the imaging of choice for asymp AAAs?
what is the imaging of choice for symptomatic AAAs?
US
CT
what is the tx for asymp AAA that is < 5.5 cm?
conservative (watchful waiting)
what is the tx for asymp AAA that is > 5.5 cm?
elective AAA repair
what is the tx for symptomatic AAAs of any size?
urgent AAA repair
what are the 3 common symptoms in pts with a ruptured AAA?
severe pain
hypotension
pulsatile abd mass
what is the tx for an unstable pt with a known AAA rupture?
immediate surgery
what is the tx for a stable pt w/ a suspected AAA rupture?
urgent abd imaging --> surgery
aneurysms that affect arteries other the aorta or brain =
what is the MC type?
peripheral aneurysms
popliteal
femoral artery aneurysms are typically PSEUDOaneurysms with the 2 main causes being what?
percutaneous vascular injection
pt self-injecting
what is the MC type of VISCERAL aneurysm?
splenic artery aneurysms
permanent localized dilation of the thoracic aorta having at least a 50% increase in diameter compared to normal
thoracic aneurysms
what percent of TAAs involve the aortic root/ascending aorta?
what percent of TAAs involve the descending aorta?
60%
40%
where are 80% of AAAs located?
infrarenal arteries
what is the imaging of choice for thoracic aneurysms?
CT
an ASYMP ascending TAA indicates repair if the end-diastolic aortic diameter is what?
> 5.5 cm
an ASYMP descending TAA indicates repair if the pt is an average sized adult w/ a diameter of what?
> 5.5 cm
separation of layers of the aortic wall
usually due to entry of blood between intima and media layers --> resulting in a tear in the intimal layer and progressed dissection
aortic dissection
T/F aortic dissection is associated with average mortality rates, have a decent chance of survival if they make it to the ER in time
false - very high mortality; often dead before recaching ER
the following combinations of symptoms should clue you in to what diagnosis?
- chest pain + neurologic finding
- chest + abdominal pain
- chest pain + limb weakness
aortic dissection
what are the 4 main sx of aortic dissection?
BP discrepency in UE
pulse defecit
HTN
diastolic murmur
what are the 2 imaging studies that are used to dx aortic dissection?
CT w/ contrast
TEE
what is the tx of a type A aortic dissection?
of a type B aortic dissection?
surgical repair
medical management
inflammatory occlusive vascular disorder involving small/medium sized arteries/veins in the distal UE and LE
thromboangiitis obliterans (buerger disease)
thromboangiitis obliterans is a triad of what?
claudication of affected extremity
raynauds
migratory superficial vein thromophlebitis
smooth, tapering lesions in distal vessels + collateral vessels at sites of occlusion are characteristic of what condition?
thromboangiitis obliterans
what are the 2 tx options for thromboangiitis obliterans?
smoking cessation
amputation
hyperplastic disorder usually in women, that affects small/medium arteries
fibromuscular dysplasia
fibromuscular dysplasia usually involves what arteries?
renal
carotid
what condition is identified on angiograph as a "string of beads"?
fibromuscular dysplasia
what is the medical tx for fibromuscular dysplasia? (2)
what is the surgical tx for fibromuscular dysplasia? (2)
ACE/ARB, antiplatelet/anticoagulant
stenting, angioplasty
rare type of autoimmune vasculitis or blood vessel inflammation that affects predominately females 20-40 yro
takayasu arteritis
ACUTE lower extremity venous disease = (2)
DVT
superficial thrombophlebitis
CHRONIC lower extremity venous disease = (2)
varicose veins
chronic venous insufficiency
periods of high venous pressure related to prolonged standing or heavy lifting
MC in women after pregnancy
varicose veins
what is the hallmark sx for varicose veins? (2)
progressive venous reflux & venous HTN
dilated tortuous superficial veins in the LE =
varicose veins
varicose veins are usually seen in which vein?
greater saphenous
what is the tx for varicose veins?
who should it not be used in?
20-30 mmHg compression stockings
pts w/ arterial disease
what are the 2 surgical tx's for varicose veins (if painful or cosmetic issue)
foam scleropathy
surgical vein stripping
condition typically involving LE edema, trophic skin changes, and discomfort due to venous HTN
chronic venous insufficiency (CVI)
what condition may look like cellulitis but will have blanching erythema with pain
chronic venous insufficiency
what are the main symptoms of chronic venous insufficiency? (4)
pitting edema
taut/shiny skin
brown pigmentation
ulcers above ankles
what is the name of the system used to classify CVI and what are the components of the following?
C0 =
C1 =
C2 =
C3 =
C4 =
C5 =
C6 =
CEAP
0= no varicose veins
1= small vv (telangiectasis)
2= large vv
3= edema
4= skin changes w/o ulcers
5= skin changes w/ healed ulcers
6= skin changes w/ active ulcers
what is the tx for CVI?
who should it not be used in?
20-30 mmHg compression stockings
pts w/ arterial disease
what is typically used to tx ulcers in pts w/ CVI?
unna boot (nonelastic circumferential bandages)