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What historical events led to the study of right hemisphere function?
WWI and WWII — studies of soldiers with missile wounds revealed behavioral and cognitive changes tied to right hemisphere damage
What was the purpose of split-brain studies in the 1960s, and what did they reveal?
To treat epilepsy by cutting the corpus callosum; they revealed hemispheric specialization but also interdependence
How do modern models view left/right hemisphere function?
As connectionist and collaborative systems rather than strictly specialized
Which artery is most often associated with RHS after stroke?
The right middle cerebral artery (MCA).
How does RHS differ from left hemisphere damage (aphasia)?
RHS affects pragmatics, prosody, and cognition, not syntax or grammar; language form is usually intact but communication is inefficient
List stereotypic behavioral symptoms of RHS.
Self-centeredness, social inappropriateness, denial of deficits, verbosity, tangential speech, poor emotional inflection, distractibility
Which two domains are most commonly impaired?
Perception and attention
Describe neglect and its impact.
Failure to attend to the left side of space; may omit left-side items in reading, writing, or drawings and bump into objects on the left
What brain regions are associated with neglect?
Most often the right parietal lobe, sometimes the thalamus or basal ganglia
How common is neglect in right hemisphere brain injury?
Occurs in 1/3 to over 4/5 of right-hemisphere injuries, but <1/4 of left-hemisphere injuries
How does left neglect affect reading/writing?
Reads only the right side, omits left letters or words, handwriting slants up to the right
What is motor neglect?
Failure to use or move the left limbs despite no weakness or sensory loss
Examples of neglect in daily life?
Eating only from one side of the plate, shaving one side, crashing into objects on the left, ignoring left-side clothing pockets
Define anosognosia
Denial of illness—patients minimize or deny impairments, sometimes denying ownership of affected limbs
What is confabulation?
Unintentional fabrication of false memories to fill gaps or explain situations—"honest lying"
Define constructional impairment.
Inability to reproduce designs or patterns without perceptual/motor deficits; drawings are fragmented and disorganized
What is topographic impairment?
Difficulty orienting to environments, following routes, or reading maps; may "talk themselves through" navigation
Differentiate geographic disorientation.
Patient recognizes surroundings but misidentifies location (e.g., thinks hospital is their home)
What is reduplicative paramnesia?
Belief that duplicate people, places, or events exist due to disordered spatial perception and visual memory
What is prosopagnosia?
Face blindness—inability to recognize familiar faces; may extend to animals or objects
How does RHS affect emotion recognition and expression?
Difficulty perceiving and expressing emotional tone in faces and voices
Define attention types.
Arousal: readiness to respond
Vigilance: sustained alertness
Orienting: directing attention
Sustained: maintaining focus
Selective: ignoring distractions
Alternating: shifting focus
Divided: handling multiple tasks
Describe tonic vs phasic alertness.
Tonic: readiness over time (minutes–hours)
Phasic: quick responses to stimuli; RHS patients may miss cues without warning signals
What are common attention assessments?
Stroop Test, Symbol Digit Modalities, Test of Everyday Attention, Cancellation tasks, Line Bisection
How does attention affect communication?
Deficits cause poor topic maintenance, turn-taking, and comprehension in conversation.
Relationship between working memory and divided attention?
Both require holding and manipulating information; divided attention often uses working memory (e.g., digits backward tasks)
How is prosody affected in RHS?
Speech becomes flat and monotonous with reduced pitch/loudness variation and limited gesture
Describe connected speech in RHS.
Tangential, rambling, fragmented; may include irrelevant or confabulatory details
How is discourse comprehension affected?
Difficulty identifying relationships, judging appropriateness, understanding implied meanings, idioms, or humor
What is the suppression deficit hypothesis?
RHS patients activate multiple meanings but fail to suppress irrelevant ones, leading to misinterpretation
List pragmatic impairments.
Poor eye contact, off-topic remarks, interruptions, talking excessively, failing to repair misunderstandings
What are social consequences of pragmatic deficits?
Reduced relationship satisfaction, smaller social networks, job loss or demotion
Key standardized RHS assessments?
RHLB-2, MIRBI-2, RICE-R, Burns Brief Inventory
What are RHLB-2 subtests?
Metaphor picture, written metaphor, humor appreciation, inferred meaning, lexical semantics, emphatic stress, discourse analysis
What is MIRBI-2 used for?
Brief 35-item screening across 10 domains; efficient for detecting RHS
Which tools assess pragmatics?
RHLB-2, RICE-R, CADL-2, Communicative Effectiveness Index
How is neglect assessed?
Cancellation tests, line bisection, clock drawing, copying tasks, Apples test, and Indented Paragraph Test
What does a left:right ratio >1 mean?
Presence and severity of left neglect
Why is RHS therapy less standardized than aphasia therapy?
Effects are diffuse, not focal; limited norms and research
How to manage denial of deficits?
Use structured tasks, clear goals, involve family, focus on environment modification and caregiver training
Why focus on functional attention training?
Context-based tasks (e.g., conversation, daily routines) generalize better than decontextualized drills
Example sustained attention task?
Vigilance drill—monitoring a screen and signaling when a stimulus appears
Example selective attention task?
Completing cancellation while background noise plays (e.g., Coffitivity audio)
Example alternating attention task?
Switching between adding and subtracting numbers when prompted
Example divided attention task?
Performing a cancellation task while listening for a target sound
Strategies to manage impulsivity?
Use stop-sign gestures, clear start/stop cues, and structured pacing
Problem-solving training steps?
Identify → brainstorm → evaluate → choose → apply → review
How to treat prosody deficits?
Model emotional intonation; patient imitates, then practices independently
Describe scanning training for left neglect.
Use highlighters or left margin markers; fade cues as scanning improves
What are "edgeness/bookness" cues?
Tactile or visual boundary markers to train internal left scanning, aiding generalization
How is video feedback used in pragmatics?
Review recorded conversations to identify and modify inappropriate behaviors
Activities to target inference failure?
Interpreting idioms, choosing humor punchlines, identifying absurdities, reasoning tasks
Why involve caregivers?
They reinforce carryover, manage environment, and support compensatory strategies
Define executive function (EF).
The cognitive system for planning, organizing, problem-solving, monitoring, and adapting behavior
Common EF symptoms post-RHS?
Poor initiation, disorganization, impulsivity, perseveration, inefficient goal management
What is resource allocation theory?
The brain has limited cognitive resources; performance drops when demand exceeds capacity
Tests assessing EF?
FAVRES, BADS, Six Elements Test, Wisconsin Card Sorting, Tower Test, Tinkertoy Test
What is the FAVRES used for?
Evaluates verbal reasoning, complex comprehension, planning, and rationale through functional tasks
Emotional and psychological effects after RHS?
Self-doubt, concreteness, emotional lability, egocentrism, frustration intolerance
Define emotional lability.
Exaggerated or uncontrollable emotional reactions disproportionate to events
Define concreteness.
Failure to interpret abstract meaning, humor, or others' perspectives; overly literal thinking