Tertiary Drug Information References Commonly Used in Sterile Compounding

select all that apply:

what does Texas law (TSBP 291.133) expect of us as pharmacists?

1. the product being right

2. inspecting/approving all components

3. reviewing compounding records

4. performing the final check

5. ensuring equipment is maintained

6. 24/7 accessibility

technicians can compound; ____________ are on the hook.

pharmacists

select all that apply:

what happens in a hospital pharmacy?

1. provider enters order

2. pharmacist verifies appropriateness

3. tech compounds

4. pharmacist final check

5. release to floor

select all that apply:

what does the pharmacist verify step actually check?

1. drug

2. dose

3. compatibility

4. concentration

5. rate

6. route

7. frequency

shows all active meds; your IV order is flagged "non-verified."

med profile

solution (e.g., D5W 250 mL), additive (e.g., norepinephrine 8 mg), final concentration (you should be able to calculate it), rate (e.g., 45 mL/hr), route (IV), and provider instructions (e.g., "start 8 mcg/min, titrate to MAP ≥ 65").

order details

select all that apply:

what do you do while reading the EHR screens?

1. convert rate ↔ dose

2. check line requirements

3. confirm correct diluent

4. ensure monitoring is clear

fast, broad: dosing by indication; warnings; preparation/administration, storage, stability, and an IV compatibility module (often powered by Trissel's). great for steps 1-7 but may be incomplete for niche drugs.

Lexicomp

gold for labeled stability, reconstitution, storage. some off-label IV use won't be here.

package insert

your compatibility bible (Y-site, syringe, admixture, solution specifics, concentrations, temps, time). core for steps 3-4.

ASHP Injectable Drug Information (Trissel's)

peds dosing, concentrations, rates—when the patient is tiny and terrifyingly cute.

Pediatric Injectable Drugs (Teddy Bear Book)

compounding standards: environment, garbing, beyond-use dates (BUDs) by risk category/sterility, QA processes (ties back to legal responsibilities on slide 2).

USP

select all that apply:

what do we do during the final check?

1. label vs order

2. physical product

3. build evidence

4. documentation