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Hormone Function
Hormones relay messages to organs and glands in the body.
Endocrine Cells
Cells responsible for chemical signaling to organs and glands.
Circulatory System Role
Transports hormones to target tissues throughout the body.
Target Cells
Cells that have specific receptors that bind to hormones.
Receptors
Locations on target cells where hormones bind.
Protein-based Hormones
Hormones that are water-soluble and cannot cross cell membranes; bind to receptors on the surface of target cells.
Steroid-based Hormones
Hormones that can cross cell membranes and have receptors inside target cells; deal with gene expression and protein production.
Insulin Action
Protein-based hormone that binds to surface receptors to increase glucose uptake in muscle cells via GLUT4 transporters.
Cortisol Action
Lipid-based hormone that binds to intracellular receptors to activate genes for gluconeogenesis in liver cells.
Negative Feedback
Regulates hormone activity by reducing secretion when the desired effect is achieved.
Positive Feedback
Amplifies a response until a specific outcome is achieved.
Thyroid Hormones
Regulate metabolism, providing negative feedback by inhibiting TSH and TRH secretion when levels are sufficient.
Spermatogenesis
The process of sperm production occurring in the seminiferous tubules of the testes.
Sertoli Cells
Support cells that provide nutrients and create the blood-testis barrier during spermatogenesis.
Leydig Cells
Cells that produce testosterone, essential for spermatogenesis.
GnRH
Gonadotropin-releasing hormone that stimulates the release of LH and FSH.
LH
Luteinizing hormone that targets Leydig cells to promote testosterone production.
FSH
Follicle-stimulating hormone that acts on Sertoli cells to stimulate spermatogenesis.
Inhibin
Hormone secreted by Sertoli cells that provides negative feedback to regulate FSH levels.